Particle Size Distribution and Human Respiratory Deposition of Trace Metals in Indoor Work Environments

Akselsson, K. Roland; Desaedeleer, G.; Johansson, Thomas B.; Winchester, John W.

doi:10.1093/annhyg/19.3-4.225

Cited by 17 publications

(1 citation statement)

References 6 publications

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“…The size of the welding particles generated differs based on the industrial processes undertaken. Earlier studies have indicated that welding particles are in the ultrafine size range of 0.01 to 0.10 μm [ 4 ] and that most of the welding fumes have particles that are <0.50 μm in aerodynamic diameter [ 5 ]. Ultrafine particles have a higher likelihood of being deposited in the smaller branches of the bronchial airways in the respiratory tract; rapid clearance by the mucociliary system is much more ineffective.…”

Section: Introductionmentioning

confidence: 99%

Exposure to Heavy Metals and Serum Adiponectin Levels among Workers: A 2-Year Follow-Up Study

Chen

et al. 2023

Metabolites

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The workers exposed to metal fumes had an increased risk of metabolic syndrome, which was correlated with decreased serum adiponectin. Thus, we aimed to explore whether heavy metal exposure affects the adiponectin level. There were 96 male workers recruited from a shipyard at baseline. Apart from 82 participants completed the follow-up assessments, new participants were recruited in next year. Finally, there were 100 welding workers in the exposure group and 31 office workers in the control group. Inferential statistics on repeated measures were performed using generalized estimating equations. A weighted quantile sum (WQS) regression model was conducted to examine the joint effect of the multimetal exposure with serum adiponectin. Significantly negative associations of metals with adiponectin were detected in the welding workers, including Cr (β = −0.088; 95% CI: −0.148, −0.027), Mn (β = −0.174; 95% CI: −0.267, −0.081), Co (β = −0.094; 95% CI: −0.158, −0.029), Ni (β = −0.108; 95% CI: −0.208, −0.008), Cd (β = −0.067; 95% CI: −0.115, −0.018), and Pb (β = −0.089; 95% CI: −0.163, −0.015). The WQS regression suggested that Pb was the greatest contributor. In conclusion, our findings highlighted that welding workers exposed to heavy metals would reduce serum adiponectin.

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Section: Introductionmentioning

confidence: 99%

Exposure to Heavy Metals and Serum Adiponectin Levels among Workers: A 2-Year Follow-Up Study

Chen

et al. 2023

Metabolites

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Origin of mutagenicity of welding fumes in S. typhimurium

Stern¹,

Thomsen

Anderson

et al. 1982

J of Applied Toxicology

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The origin of mutagenicity in S. typhimurium in response to exposure to welding fumes, a complex mixture of metallic oxides and other inorganic compounds, was studied through the quantitative use of the histidine revertant Salmonella microsome test of Ames. Dose-response experiments and factorial design studies independently showed the mutagenic activity to be due to the presence of soluble Cr(V1). A rate of 65 f 1 5 revertants per plate per pg Cr(V1) was found for all fumes produced by the metal inert gas welding of stainless steel. A significantly reduced rate was found for manual metal arc welding fumes. The presence of other metals in low oxidation states (e.g. Fe(O), Fe(II), A1(0)), results in a significant reduction of the Cr(VI), accompanied by a corresponding decrease of the absolute revertant rate per unit fume mass. INTRODUCTIONLarge numbers of workers are exposed to the fumes from welding, a technology for the joining of metals which has been in widespread use for more than fifty years. Welding fumes consist of mono-or bidispersed aerosols containing a complex mixture of multiphase particles whose chemistry and size distribution are determined by the process technology and consumable chemistry used in each c a~e . l -~ Although there are very many types of welding, two major technologies used on two classes of material account for perhaps 70% of the worldwide welding activity.The metal inert gas (MIG) welding of mild steel (MS), using a shielding curtain of argon, produces a relatively homogeneous aerosol with mass median diameter (MMD) of approximately 0.2 p. The particulates are composed of highly crystalline iron oxide spinel, with up to several percent of other alloying elements, typically Mn and Si, with trace impurities of many elements e.g. Cu, Zn, Pb etc. In the case of MIG welding on stainless steel (SS), the additional alloying elements Cr and Ni appear in relatively high concentrations, and are characteristic for all fumes used on high alloy steels. In manual metal arc welding (MMA), the core wire is surrounded by an electrode coating whose decomposition provides protection against oxidation in the arc region, the liquefied residue covering the weld with a protective slag layer. This coating provides a second aerosol source, mostly by means of atomization of the molten slag layer by the plasma jet: the particulates formed thereby are typically composed of a metal rich (po1y)-crystalline core surrounded by a glassy matrix composed of light elements such as Ca, F, K etc., or are spongy cenospheres. These light elements are found in a separate aerosol having a MMD of 2 p . Less than 1% of the mass of fresh fumes is found in particles larger than 5 p in diameter,3t Author to whom correspondence should be addressed, although the formation of long (> 20 p) chains is characteristic for the condensation process:334 a considerable amount of ejecta (spray) can be produced under certain (usually improper) welding conditions.A number of factors affect the concentration of fumes to which a welder can be...

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