Partial VP2 sequencing of canine parvovirus (CPV) strains circulating in the state of Rio de Janeiro, Brazil: detection of the new variant CPV-2c

Abstract

Canine parvovirus (CPV) is the most important enteric virus for dogs and it seems to be undergoing

A phylogenetic study of canine parvovirus type 2c in midwestern Brazil

“…However, CPV-2c has been detected in epidemiological surveys conducted in South America (Pérez et al 2007) including Southern (Streck et al 2009) and Southeast region of Brazil (Castro et al 2010). This article constitutes the first to provide information about CPV-2c infection in dogs from the Mato Grosso State in Midwestern Brazil.…”

Canine parvovirus: the worldwide occurrence of antigenic variants

“…CPV-2a was the predominant variant during 1980-1986, which was substantially replaced by CPV-2b from 1990 to 1995 (Pereira et al, 2000). (Castro et al, 2010), and that become the most predominant variant circulating in Brazil between 2008 and 2010 (Pinto et al, 2012).…”

“…In recent years, several other mutations have been reported around the world simultaneously within the VP2 region (Pinto et al, 2012;Yi et al, 2014). For example, the amino acid substitution Thr440Ala has been described in CPV-2a and -2b strains from India, Brazil, South Africa and China (Chinchkar et al, 2006;Castro et al, 2010;Dogonyaro et al, 2013;Yi et al, 2014) and in CPV-2c strains from the USA (Hong et al, 2007) and Argentina (Calderón et al, 2011). The 440 position is an important residue because it is located at the top of the threefold spike, the main antigenic site of the virus (Tsao et al, 1991).…”

Isolation and characterization of canine parvovirus type 2c circulating in Uruguay

“…It was previously reported that this is the predominant variant in Uruguay (PEREZ et al, 2007), Argentina (CALDERON et al, 2009) andBrazil (STRECK et al, 2009;CASTRO et al, 2010). To our knowledge the isolation in cell culture of CPV-2c strain was not described in the neighboiring countries, therefore this research is the first report in Uruguay and in the region about CPV-2c isolation in A-72 canine cell line.…”