Isolation and characterization of canine parvovirus type 2c circulating in Uruguay

Pintos, Andrea Blanc; Larrama, Cecilia Beatriz Negro; Baratta, Eduardo Enrique Reolon; Barthe, Mabel Beatriz Berois; Rodonz, Juan Ramón Arbiza

doi:10.1590/s0103-84782011005000098

Cited by 5 publications

(2 citation statements)

References 20 publications

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“…CPV-2c had also been reported in Vietnam [12], Spain [23], Germany [27], United Kingdom [28] South America [24], United States of America [29], Central Portugal [30], Argentina [31], Greece [32], North India [14], Brazil [33] and Uruguay [34,35]. Recent reports revealed the predominant CPV strain in India as new CPV-2a (Ser 297Ala) with one new CPV-2b (Ser 297Ala) and another new CPV-2a (Ser 297Gly) variant strain [36].…”

Section: Epidemiologymentioning

confidence: 95%

“…The A-72 cell line was widely used for cultivation of CPV in cell culture and the first CPV-2c was isolated in A-72 cell line in Uruguay [10,34,[57][58][59]. A-72 cell lines was used for isolation of CPV from samples found positive by PCR, CPE was observed in A-72 cell line from second passage onwards showing greater sensitivity of A-72 cell line over CRFK cell line [60].…”

Section: Isolation Of Cpv In A-72 Cell Linementioning

confidence: 99%

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Isolation and Molecular Characterization of Canine and Feline Parvovirus Strains - An Updated Review

Brindhalakshmi¹

2016

JDVAR

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Section: Epidemiologymentioning

confidence: 95%

Section: Isolation Of Cpv In A-72 Cell Linementioning

confidence: 99%

Isolation and Molecular Characterization of Canine and Feline Parvovirus Strains - An Updated Review

Brindhalakshmi¹

2016

JDVAR

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Dynamic evolution of canine parvovirus in Thailand

et al. 2020

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Background and Aim: According to the previous study, the circulating canine parvovirus (CPV) in Thailand is 2a and 2b. Nowadays, CPV mutants, including CPV-2c, have been identified in many parts of the world. This study aimed to investigate the genetic diversity of the circulating CPV in Thailand. Materials and Methods: Eighty-five CPV-positive fecal samples were obtained from dogs with either acute hemorrhagic diarrhea or diarrhea. The complete VP2 gene of these samples was amplified using VP2 specific primers and polymerase chain reaction (PCR). The obtained full-length VP2 sequences were analyzed and a phylogenetic tree was constructed. Results: Sixty and 25 CPV-positive fecal samples were collected in 2010 and 2018, respectively. Thirty-four samples were new CPV-2a and 31 samples were new CPV-2b due to amino acids substitution at position 297 (Ser-Ala). In 2018, 5 new CPV-2a, 19 CPV-2c, and 1 feline panleukopenia virus (FPV) were found, but no new CPV-2b was detected. Moreover, most of the CPV in this study had amino acids mutations at positions 324 and 440. The phylogenetic construction demonstrated the close relationship between the current new CPV-2a with the previous CPV-2a reported from Thailand, China, Uruguay, Vietnam, Singapore, and India. Interestingly, the current new CPV-2b in this study was not closely related to the previous CPV-2b reported in Thailand. The CPV-2c in this study was closer to Asian CPV-2c and further from either European or South America CPV-2c. Interestingly, FPV was identified in a diarrhea dog. Conclusion: The evolution of CPV in Thailand is very dynamic. Thus, it is important to monitor for CPV mutants and especially the clinical signs relating to these mutants to conduct surveillance for the emergence of new highly pathogenic CPV in the future.

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Systemic inflammatory response syndrome: a risk factor associated with poor prognosis of dogs infected with canine parvovirus 2

Melo,

Rodrigues,

Abreu

et al. 2024

Cienc. Rural

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Canine parvovirus 2 (CPV-2) is a highly contagious enteric virus that causes high morbidity and mortality, especially in dogs under six months of age. Recovery from this illness is dependent on several factors, including the patient’s prognosis for adequate therapy. The aim of this study was to evaluate the risk factors associated with the death outcome in CPV-2 positive dogs in a case-control study conducted at the Veterinary Hospital of the Universidade Federal de Lavras (HV-UFLA) in Lavras, Minas Gerais, Brazil. Twenty-six dogs with CPV-2 symptoms that arrived at the HV-UFLA between 2017 and 2018 were evaluated for inclusion in the study. Data on medical history, clinical signs, blood count and rapid test of parvovirus and faecal test for polymerase chain reaction (PCR) were collected for all the animals. All the dogs received treatment at the HV-UFLA, and the overall fatality rate due to canine parvovirus was 30.77%. Descriptive analysis and univariate and multivariate statistical analyses (logistic regression) were performed to assess the variables that were possibly associated with an unfavourable prognosis (death). In the univariate and multivariate analyses, Systemic Inflammatory Response Syndrome (SIRS) was observed to be a significant risk factor for an unfavourable prognosis in canine parvovirus, as it increased the risk of death by 12.96 times (95% CI 1.85-133.70; P < 0.01) compared with patients who did not exhibit SIRS. Thus, SIRS was strongly associated with an unfavourable prognosis, suggesting that it can be used as a prognostic indicator for canine parvovirus in veterinary practice.

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Isolation and characterization of canine parvovirus type 2c circulating in Uruguay

Cited by 5 publications

References 20 publications

Isolation and Molecular Characterization of Canine and Feline Parvovirus Strains - An Updated Review

Isolation and Molecular Characterization of Canine and Feline Parvovirus Strains - An Updated Review

Dynamic evolution of canine parvovirus in Thailand

Systemic inflammatory response syndrome: a risk factor associated with poor prognosis of dogs infected with canine parvovirus 2

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