Parkinsonian axial signs in schizophrenia

Morgante, Francesca; Barbui, Corrado; Tinazzi, Michèle

doi:10.1016/j.parkreldis.2016.12.022

Cited by 5 publications

(2 citation statements)

References 12 publications

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“…Current data assume that negative and cognitive symptoms in schizophrenia anticipate the onset of positive symptoms, decreased dopamine may be responsible for these, suggesting that schizophrenia may essentially represent a hypodopaminergic disorder after all [ 19 , 20 ]. On the other hand a few studies have proposed the idea that parkinsonism in schizophrenia may not be just the consequence of neuroleptic exposure but it could be also related to the clinical spectrum and might represent the motor side of schizophrenia manifesting in the late phase of disease course [ 21 – 23 ].…”

Section: Discussionmentioning

confidence: 99%

The prevalence of psychiatric symptoms before the diagnosis of Parkinson’s disease in a nationwide cohort: A comparison to patients with cerebral infarction

et al. 2020

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Section: Discussionmentioning

confidence: 99%

The prevalence of psychiatric symptoms before the diagnosis of Parkinson’s disease in a nationwide cohort: A comparison to patients with cerebral infarction

et al. 2020

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“…Smokers with schizophrenia were older than nonsmokers [ 17 ]. Given the self-medication hypothesis of smoking in schizophrenia [ 20 ], it might be speculated that older patients smoked more often in order to alleviate extrapyramidal and depressive symptoms, which are related to longer disease duration [ 40 , 41 ]. However, other studies on individuals with schizophrenia have reported that smokers were actually younger than nonsmokers [ 14 , 16 ].…”

Section: Discussionmentioning

confidence: 99%

Nicotine dependence in Croatian male inpatients with schizophrenia

et al. 2018

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BackgroundPatients with schizophrenia have the highest known rates of cigarette smoking, but less is known about their smoking behavior and the differences across geographical regions, including Croatia.The aim of this study was to compare patterns of nicotine dependence between patients with schizophrenia and healthy individuals, and to determine the relationship between clinical presentation and the severity of smoking.MethodsThis cross-sectional study included 182 recently hospitalized male inpatients and 280 healthy males, who were daily smokers. All participants have fulfilled the Fagerstrom Test for Nicotine Dependence (FTND). Patients were also evaluated by the Positive and Negative Syndrome Scale (PANSS).ResultsPatients had higher FTND total score (p = 0.010), smoked their first cigarette earlier in the morning (p = 0.000), consumed higher number of cigarettes (p = 0.000), while healthy subjects had more difficulties to refrain from smoking in places where it is forbidden (p = 0.000) and smoked more even when they were sick (p = 0.000). While severe dependence was more prevalent in the patient group, light dependence was more frequent in control subjects (p = 0.04). Smoking behavior was not associated with either PANSS total score or any of its subscales and items.ConclusionsSmokers with schizophrenia differ from healthy smokers in both smoking behavior and level of dependence. Longitudinal studies are needed to shed more light on the complex relationship between smoking and psychopathology in schizophrenia.

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Motor System Pathology in Psychosis

Walther

Mittal

2017

Curr Psychiatry Rep

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Instrumental measures of fine motor performance, balance, spontaneous motor activity, and gesture indicated motor abnormalities in subjects at risk and across stages of schizophrenia. Motor phenomena are associated with distinct symptom dimensions and may indicate poor outcomes. Neuroimaging studies demonstrated altered neural maturation within critical motor networks in subjects at risk. Furthermore, specific categories of motor dysfunction were associated with distinct structural and functional alterations in the motor system in schizophrenia. Motor abnormalities provide a unique window into the pathobiology of psychosis and have the potential to guide screening, staging, and outcome prediction.

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Parkinsonian axial signs in schizophrenia

Cited by 5 publications

References 12 publications

The prevalence of psychiatric symptoms before the diagnosis of Parkinson’s disease in a nationwide cohort: A comparison to patients with cerebral infarction

The prevalence of psychiatric symptoms before the diagnosis of Parkinson’s disease in a nationwide cohort: A comparison to patients with cerebral infarction

Nicotine dependence in Croatian male inpatients with schizophrenia

Motor System Pathology in Psychosis

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