Parental Pesticide Exposure and Childhood Brain Cancer: A Systematic Review and Meta-Analysis Confirming the IARC/WHO Monographs on Some Organophosphate Insecticides and Herbicides

Feulefack, Joseph; Khan, Aiza; Forastiére, Francesco; Sergi, Consolato

doi:10.3390/children8121096

Cited by 18 publications

(13 citation statements)

References 65 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A variety of pesticides are prohibited because they are not biodegradable and impact human health [ 162 ]. Chemical pesticides were also identified as causing birth defects in children and cancer [ 163 , 164 ]. The contamination of organochloride pesticides in food products and water are also concerning, due to the danger in long-range transport, bioaccumulation in human and animal tissue, and biomagnification in food chains [ 165 ].…”

Section: Nanotechnology In Food Monitoringmentioning

confidence: 99%

Recent Progress in Nanotechnology-Based Approaches for Food Monitoring

et al. 2022

View full text Add to dashboard Cite

Throughout the food supply chain, including production, storage, and distribution, food can be contaminated by harmful chemicals and microorganisms, resulting in a severe threat to human health. In recent years, the rapid advancement and development of nanotechnology proposed revolutionary solutions to solve several problems in scientific and industrial areas, including food monitoring. Nanotechnology can be incorporated into chemical and biological sensors to improve analytical performance, such as response time, sensitivity, selectivity, reliability, and accuracy. Based on the characteristics of the contaminants and the detection methods, nanotechnology can be applied in different ways in order to improve conventional techniques. Nanomaterials such as nanoparticles, nanorods, nanosheets, nanocomposites, nanotubes, and nanowires provide various functions for the immobilization and labeling of contaminants in electrochemical and optical detection. This review summarizes the recent advances in nanotechnology for detecting chemical and biological contaminations in the food supply chain.

show abstract

Section: Nanotechnology In Food Monitoringmentioning

confidence: 99%

Recent Progress in Nanotechnology-Based Approaches for Food Monitoring

et al. 2022

View full text Add to dashboard Cite

show abstract

“…The toxicity to human and other non-target species may be due to their poor selectivity to target species and the similarities of all organisms in the basic biological processes. As a result, the International Agency for Research on Cancer (IARC) classified some pesticides, such as diazinon, glyphosate, and malathion (8, 9), being possible human carcinogens as shown in human epidemiological studies and experimental animal data, and the use of various pesticides were banned or strictly regulated (e.g. US-EPA, Dir.…”

Section: Introductionmentioning

confidence: 99%

Investigating the genotoxicity of occupational pesticide exposures in Arab countries: Protocol of a systematic review and meta-analysis

Sherif

Makame

Östlundh

et al. 2022

Preprint

View full text Add to dashboard Cite

Background Tens of millions of agricultural workers are directly exposed to pesticides through handling pesticide products, mostly in developing countries. Systematic data synthesis on the genotoxic consequences of such occupational exposures and their human health risks in agricultural settings is required in Arab countries. We aim to conduct a systematic review and, if possible, a meta-analysis to review published literature about the genotoxicity of occupational pesticide exposures in Arab countries, with the objectives of characterising the (1) prevalence rates of genotoxic pesticide exposures, (2) extent of genotoxic insult, (3) attributed risk factors, and (4) preventive measures against pesticide-induced genotoxic effects detectable by biomonitoring. Methods The research will follow the guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols (PRISMA-P) statement. A comprehensive search will be conducted in November 2022 in the electronic databases PubMed (NLM), EMBASE (Elsevier), Web of Science (Clarivate), Scopus (Elsevier), and Agricola in addition to WHO Index Medicus for the Eastern Mediterranean (IMEMR). The search will be performed without any restrictions for publication years. A filter for English and Arabic language will be applied. The systematic search will include agricultural workers over the age of 18 years, located in Arabic speaking countries of the Middle East and North Africa (MENA) region, occupationally exposed to pesticides inducing genotoxic insult detectable by biomonitoring. Records identified in the search will be imported into the systematic review tool Covidence for blinded screening and selection by two reviewers independently. The reviewers will then extract data and conduct risk of bias assessment using the Navigation Guide RoB tool and the RoB-SPEO tool. The results will be synthetized narratively in summary tables, and, if findings allow, meta-analysis, including subgroup and sensitivity analysis, will be conducted on the prevalence of genotoxic pesticide exposures, and on the effect size of risk factors. The systematic review methodology does not require ethics approval. Discussion The systematic review will consider various types of pesticide exposures and genotoxicity biomarker assays to determine prevalence and extent of such occupational genotoxic insults, the correlation between genetic damage and various risk factors, e.g. work conditions, types of pesticides, environmental exposure routes, and the applied preventive measures. The review will provide gap-filling information about genotoxic pesticide exposures of agricultural workers in the local context, as well as it will contribute to our general knowledge on pesticide genotoxicity. Systematic review registration PROSPERO registration number: CRD42022314453 .

show abstract

“…Glyphosate exposure has been linked to an increased risk of non-Hodgkin’s lymphoma, endocrine disruptions, and chromosomal damage [ 4 , 5 ]. Feulefack et al [ 6 ] confirmed an association between prenatal exposure to organophosphate herbicides and childhood brain tumors. Although glyphosate application has been banned or regulated in many countries, its usage and human exposure to glyphosate-based herbicides continue to rise.…”

Section: Introductionmentioning

confidence: 99%

Surface Plasmon Resonance Imaging Sensor for Detection of Photolytically and Photocatalytically Degraded Glyphosate

Vráblová

Smutná

Koutník

et al. 2022

Sensors

View full text Add to dashboard Cite

Glyphosate is one of the most widely used pesticides, which, together with its primary metabolite aminomethylphosphonic acid, remains present in the environment. Many technologies have been developed to reduce glyphosate amounts in water. Among them, heterogeneous photocatalysis with titanium dioxide as a commonly used photocatalyst achieves high removal efficiency. Nevertheless, glyphosate is often converted to organic intermediates during its degradation. The detection of degraded glyphosate and emerging products is, therefore, an important element of research in terms of disposal methods. Attention is being paid to new sensors enabling the fast detection of glyphosate and its degradation products, which would allow the monitoring of its removal process in real time. The surface plasmon resonance imaging (SPRi) method is a promising technique for sensing emerging pollutants in water. The aim of this work was to design, create, and test an SPRi biosensor suitable for the detection of glyphosate during photolytic and photocatalytic experiments focused on its degradation. Cytochrome P450 and TiO2 were selected as the detection molecules. We developed a sensor for the detection of the target molecules with a low molecular weight for monitoring the process of glyphosate degradation, which could be applied in a flow-through arrangement and thus detect changes taking place in real-time. We believe that SPRi sensing could be widely used in the study of xenobiotic removal from surface water or wastewater.

show abstract

Parental Pesticide Exposure and Childhood Brain Cancer: A Systematic Review and Meta-Analysis Confirming the IARC/WHO Monographs on Some Organophosphate Insecticides and Herbicides

Cited by 18 publications

References 65 publications

Recent Progress in Nanotechnology-Based Approaches for Food Monitoring

Recent Progress in Nanotechnology-Based Approaches for Food Monitoring

Investigating the genotoxicity of occupational pesticide exposures in Arab countries: Protocol of a systematic review and meta-analysis

Surface Plasmon Resonance Imaging Sensor for Detection of Photolytically and Photocatalytically Degraded Glyphosate

Contact Info

Product

Resources

About