Parental Alcoholism, Adverse Childhood Experiences, and Later Risk of Personal Alcohol Abuse among Chinese Medical Students

Xiao, Qin; Dong, Maxia; Yao, Jianjun; Li, W. X.; Ye, Dong-Qing

doi:10.1016/s0895-3988(08)60062-8

Cited by 42 publications

(44 citation statements)

References 16 publications

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“…Even for young children parental alcohol abuse, especially among fathers, has shown to be associated with negative effects as evidenced in subsequent anxiety/depression symptoms influenced via greater levels of marital aggression [11]. A cross-sectional study on a large group of medical students confirmed that there is a strong relationship among parental alcoholism, adverse childhood experience, and subsequent personal alcohol abuse [12]. The results of a study on the impact of adverse childhood experiences on a wide variety of health behaviours and outcomes, showed that adults who grew up with both an alcohol-abusing mother and father had the highest likelihood of multiple forms of adverse childhood experiences, such as abuse, neglect, and other household dysfunctions as compared to those who had only one- or no alcohol-abusing parent [13].…”

Section: Introductionmentioning

confidence: 99%

Family psychosocial characteristics influencing criminal behaviour and mortality - possible mediating factors: a longitudinal study of male and female subjects in the Stockholm Birth Cohort

et al. 2011

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BackgroundFamily psychosocial characteristics in childhood have been associated with children's development into criminal behaviour and mortality. This study explored these possible relationships and examined alcohol and/or drug use and mental problems as possible mediating factors, highlighting gender-specific patterns.MethodsData from Swedish subjects born in 1953 (n = 14,294) from the Stockholm Birth Cohort study were examined. Several indicators of adverse family factors and individual problems were included in the present study. The information was derived from various data sources, covering different periods. Gender-specific associations with incidence of criminality (1966-1980) and mortality (1981-2009) were analysed using logistic regression. Furthermore, the population attributable fraction (PAF) was calculated for all variables in the fully adjusted models which were positively related to the outcome.ResultsOverall incidence of criminality and mortality was (m/f 32.3/6.6) and (m/f 6.1/3.5), respectively. The results showed that all aspects of family psychosocial and individual problems studied were associated with criminality for both genders. Among males, individual problems seemed to partly mediate these relations, but the associations remained statistically significant. Interestingly, the PAF analysis revealed a reduction in criminality of 17.5% when individual problems with alcohol and/or drug use were considered. Among females, a significant impact of alcohol and/or drug use on the association between family psychosocial characteristics and subsequent criminality was obtained. Inclusion of father's occupational class only somewhat reduced the estimates for the genders. Concerning male mortality, father's alcohol abuse was significantly related to an increased risk. When individual criminality was accounted for, the association was substantially reduced but remained statistically significant. Among females, when adjusting for family psychosocial factors, only the association between parents' mental problems and females' mortality was significant. None of the individual problem variables managed to explain this association.ConclusionsFamily psychosocial characteristics were associated with both subsequent criminal behaviour and mortality. These connections were partly explained by individual risk factors, especially by alcohol and/or drug use. The practical implications of the findings point to the importance of addressing the individual's alcohol and/or drug use in reducing criminal behaviour, which would also lower the mortality rates.

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Section: Introductionmentioning

confidence: 99%

Family psychosocial characteristics influencing criminal behaviour and mortality - possible mediating factors: a longitudinal study of male and female subjects in the Stockholm Birth Cohort

et al. 2011

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“…Os 18 estudos da amostra final foram distribuídos segundo o ano de publicação, da seguinte forma: nenhuma publicação em 2005;,uma em 2006 (11) , quatro em 2007 (12)(13)(14)(15)(16) , 8 em 2008 (17)(18)(19)(20)(21)(22)(23)(24) e 4 em 2009 (25)(26)(27)(28) .…”

Section: Resultsunclassified

“…Os países que mais desenvolveram estudos na área temática descrita foram os Estados Unidos com 11 artigos (13-14;19-20,22,24-26,28) e Coreia (23,27) , com 2 artigos; mas ainda foram desenvolvidos artigos na Dinamarca (15) , China (18) , Espanha (17) , Alemanha (16) e Holanda (21) , cada país com uma produção. Quanto ao tipo de estudo usado, houve predominância de estudos longitudinais (11,15,(20)(21)(22)(24)(25) , caso e controle (18,26) e transversal (12,(19)(20) . Destaca-se, em relação à abordagem metodológica, um estudo realizado durante 21 anos por meio de avaliação intergeracional (14) (3 gerações) e estudos que avaliaram o alcoolismo apenas maternal (21,26) .…”

Section: Resultsunclassified

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Alcoolismo parental e fatores de risco associados

Wandekoken

Vicente

Siqueira

2011

SMAD, Rev. Eletrônica Saúde Mental Álcool Drog. (Ed. port.)

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O uso indevido de álcool, de forma precoce torna-se um fator predisponente para problemas de saúde, sociais e econômicos. Face a isso, esta pesquisa buscou identificar condições de risco relacionadas às crianças e adolescentes expostos ao alcoolismo parental. Foi realizada revisão sistemática, por meio dos descritores alcoolismo, fatores de risco e filhos, de artigos publicados nos anos de 2005 a 2009, nas bases de dados LILACS, MEDLINE, SciELO e Adolec. Constataram-se problemas em relação ao uso de álcool pelos filhos, em relação ao comportamento e/ou em relação aos fatores emocionais dos filhos, implicando na necessidade de discussão do tema, a fim de contribuir para a formulação de políticas públicas destinadas a essa população.Descritores: Alcoolismo; Fatores de Risco; Relações Pais-Filho.

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“…2). Alcohol is readily absorbed from the gastrointestinal tract, circulated rapidly, and distributed uniformly throughout the body 23 . Thereafter, 80–90% of the alcohol absorbed is rapidly oxidized to acetaldehyde and acetate by enzymes in the liver such as alcohol dehydrogenase and aldehyde dehydrogenase 24 .…”

Section: Discussionmentioning

confidence: 99%

Effects of the herb mixture, DTS20, on oxidative stress and plasma alcoholic metabolites after alcohol consumption in healthy young men

Hong

2016

Integrative Medicine Research

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BackgroundThis study was designed to investigate the effect of a herbal mixture extract (DTS20) on the attenuation of oxidative stress and hangover after alcohol consumption in healthy volunteers.MethodsDTS20 consists of Viscum album L. (40%), Lycium chinense L. (30%), Inonotus obliquus (20%), and Acanthopanax senticosus H. (10%). We recruited healthy, nonsmoking, adult men volunteers aged between 21 years and 30 years to participate in a crossover trial. Twenty participants received either one package of placebo with 200 mL water or DTS20 with 200 mL water. Thirty minutes later, the volunteers ingested one bottle of Soju, which is a commercially available liquor (19% alcohol in 360 mL).ResultsVolunteers received the opposite treatment after a 1-week washout period. DTS20 is mainly composed of sugars (564.5 mg/g) and polyphenol (28.2 mg/g). Alcohol levels in the DTS20 group were significantly lower than the control group at 2 hours after drinking Soju (p < 0.05). Acetaldehyde levels in the DTS20 group tended to be lower than the control group at 2 hours after drinking Soju, but was not significantly different. The antioxidant activity level was also significantly different between the control and DTS20 group 2 hours after drinking Soju (p < 0.05). No differences in plasma alanine transaminase or aspartate transaminase levels were observed between plasma levels before drinking and 2 hours after drinking Soju in the control group.ConclusionIt was concluded that DTS20 reduced oxidative stress and hangover by mitigating plasma alcohol concentrations and elevating antioxidative activity in healthy male adults.

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Parental Alcoholism, Adverse Childhood Experiences, and Later Risk of Personal Alcohol Abuse among Chinese Medical Students

Cited by 42 publications

References 16 publications

Family psychosocial characteristics influencing criminal behaviour and mortality - possible mediating factors: a longitudinal study of male and female subjects in the Stockholm Birth Cohort

Family psychosocial characteristics influencing criminal behaviour and mortality - possible mediating factors: a longitudinal study of male and female subjects in the Stockholm Birth Cohort

Alcoolismo parental e fatores de risco associados

Effects of the herb mixture, DTS20, on oxidative stress and plasma alcoholic metabolites after alcohol consumption in healthy young men

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