Paracoccidioidomycosis Mimicking Squamous Cell Carcinoma on the Dorsum of the Tongue and Review of Published Literature

Abstract

Correct diagnosis is essential for a successful therapeutic approach and resolution of the lesion.

Disseminated paracoccidioidomycosis associated with lymph node tuberculosis in a non immunocompromised child

“…Although the association between PCM and TB is reported in the literature, this infectious combination should be considered mainly in tropical and PCM endemic areas where about 8% of patients with pulmonary PCM presented coinfection with pulmonary TB with a positive sputum result [8] , mainly when there is failure of the initial treatment of any of them or when the presentations cause invasion of multiple organs such as bone marrow, kidney, brain, skin and other organs with great systemic involvement [9] , [10] and in patients with immunosuppression such as infection due to HIV [11] or diabetes mellitus [12] the clinical picture is very aggressive or the clinical presentation can mimic neoplastic diseases [13] and in some cases as added comorbidities in patients with lymphoma.…”

Serum antibody levels correlate with oral fungal cell numbers and influence the patients' response to chronic paracoccidioidomycosis

“…The identification of Pb in oral lesions is achieved with tissue staining directed to polysaccharides located on the fungal cell wall, such as periodic acid‐Schiff and Grocott methenamine silver staining; these histochemical reactions elicit double contoured, round‐shaped structures, commonly exhibiting peripheral buds . Nevertheless, the detection rate of some fungi with immunohistochemical staining is greater than that with Grocott staining .…”

Importance of differential diagnosis of pulmonary and oral infections in times of COVID 19: a clinical case report

“…[2][3][4] Oral manifestations occur due to the hematogenous spread of the fungus and are characterized mainly by moriform stomatitis described by Aguiar Pupo, being a stomatological condition of slow evolution with the presence of fine erythematous granulations affecting mainly the lips, jugal mucosa, tongue and palate. [4][5][6][7] Due to the coronavirus pandemic (COVID-19), images suggestive of pulmonary involvement have caused doctors to have this disease among their main diagnostic hypotheses, however, a thorough clinical examination must be performed so that other pathological conditions that also affect the lungs are diagnosed and treated. 8…”