Abstract:Genus Pantoea is a rare pathogen in clinical settings. Among seven species of the rare organism, Pantoea agglomerans is the most prominent species in humans and clinical cases of Pantoea dispersa infection have scarcely been described. First case was reported in Germany in a 71-year-old woman with respiratory infection, 1 and recently, Mehar et al. described two neonatal cases in India. 2 We herein report another clinical case of P. dispersa infection from Japan.A 64-year-old man with dilated cardiomyopathy, s… Show more
“…Some Pantoea species, such as Pantoea dispersa , are used as plant growth‐promoting rhizobacteria (PGPR) . Both S. marcescens (2.7%) and P. dispersa (1.4%) were isolated from pulp samples in the present study and have already been described as facultative pathogenic bacteria for humans …”
Section: Resultsmentioning
confidence: 72%
“…62 Both S. marcescens (2.7%) and P. dispersa (1.4%) were isolated from pulp samples in the present study and have already been described as facultative pathogenic bacteria for humans. 63,64 As described by Iniguez et al 65 , Klerks et al 15 and Roy et al 14 , internalization of some microorganisms depends both on the microorganism itself and on the plant. Some bacteria, such as E. coli O157:H7, were easily recognized as foreign organisms by Arabidopsis thaliana, and a more intense immune reaction was provoked and internalization could be inhibited.…”
Section: Other Microorganisms Isolated From Melon Pulpmentioning
“…Some Pantoea species, such as Pantoea dispersa , are used as plant growth‐promoting rhizobacteria (PGPR) . Both S. marcescens (2.7%) and P. dispersa (1.4%) were isolated from pulp samples in the present study and have already been described as facultative pathogenic bacteria for humans …”
Section: Resultsmentioning
confidence: 72%
“…62 Both S. marcescens (2.7%) and P. dispersa (1.4%) were isolated from pulp samples in the present study and have already been described as facultative pathogenic bacteria for humans. 63,64 As described by Iniguez et al 65 , Klerks et al 15 and Roy et al 14 , internalization of some microorganisms depends both on the microorganism itself and on the plant. Some bacteria, such as E. coli O157:H7, were easily recognized as foreign organisms by Arabidopsis thaliana, and a more intense immune reaction was provoked and internalization could be inhibited.…”
Section: Other Microorganisms Isolated From Melon Pulpmentioning
“…[ 14 ] In 2014, there was a reported case of P dispersa , being the cause of bacteremia via a central line, again an opportunistic invasion. [ 15 ] Surprisingly, in another report from Iraq, the majority of samples contained P. agglomerans , followed by Pantoea ananatis and Pantoea calida . Their conclusion was that these are the opportunistic, MDR microorganisms commonly causing the nosocomial infections.…”
“…Our results correspond to the findings of Cheng et al (ampicillin susceptibility: 56%, cefazolin susceptibility: 61%, other antibiotics: 100%), Cruz et al (ampicillin susceptibility: 47.2%, cefazolin susceptibility: 62.3%, second-generation cephalosporins: 92.5%, other antibiotics: 100%), and other case studies reporting on Pantoea spp. infections [2][3][4][5][6]8]. In the study of Mardaneh and Dallal [15], 12.5% of isolates were susceptible to ampicillin, 62.5% were susceptible to meropenem and amikacin, 75% were susceptible to gentamicin and piperacillin-tazobactam, and 100% were susceptible to colistin and tigecycline.…”
Section: Discussionmentioning
confidence: 99%
“…It is generally considered a rare, opportunistic pathogen with low virulence, mainly implicated in nosocomial outbreaks affecting neonates and immunocompromised patients [4,5]. Most of the affected patients in the literature had severe underlying illnesses (hematological malignancies or solid tumours, manifest AIDS); however, infections associated with penetrative trauma, contaminated intravascular catheters and fluids (dialysis and intravenous anesthesia), and agricultural occupation have also been reported [1,4,6,7]. In addition, associations of P. agglomerans bacteremia with antacid/proton pump inhibitor use (corresponding to a decreased protective effect of gastric acid) and gastrointestinal mucosal injury have been described, which may be attributable to the abundance of P. agglomerans on fruits or vegetables [4,8].…”
Purpose
Pantoea species are pigmented, Gram-negative rods belonging to the Enterobacterales order. They are considered rare, opportunistic pathogens and are mostly implicated in nosocomial outbreaks affecting neonates and immunocompromised patients. The aim of this study was to describe the prevalence and antibiotic susceptibility of Pantoea species during a 12-year period.
Materials and methods
This retrospective study was carried out using microbiological data collected between January 1, 2006 and December 31, 2017. Patients’ data such as age, sex, inpatient/outpatient status, and empiric antibiotic therapy were also collected. Antimicrobial susceptibility testing was performed using E-tests; the interpretation was based on European Committee on Antimicrobial Susceptibility Testing breakpoints for Enterobacterales.
Results
Seventy individual Pantoea spp. isolates were identified; the most frequently isolated species was Pantoea agglomerans. Most isolates were susceptible to relevant antibiotics. In 61 out of 68 patients, ampicillin was the empirically administered antibiotic. The highest levels of resistance were to amoxicillin–clavulanic acid and ampicillin. No extended spectrum beta-lactamase-positive isolate was detected.
Conclusions
There is a scarcity of data available on the susceptibility patterns of Pantoea species, but our results correspond to what we could find in the literature. The development of multidrug-resistant (MDR) Gram-negative bacteria is a grave concern, and the development of MDR Pantoea spp. may be expected in the future.
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