Pantoea dispersa it the next emerging “monster” in our intensive care units? A case report and review of literature

Panditrao, Mridul M; Panditrao, Minnu M

doi:10.4103/aer.aer_147_18

Cited by 7 publications

(6 citation statements)

References 15 publications

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“…It was believed that P. dispersa lives in plants, soil and water and rarely caused human infections until a first neonatal sepsis was reported from India [ 32 ] and later adult sepsis in Japan [ 33 ]. Another case report from India showed that P. dispersa was detected in a septic patient admitted to ICU; this was reported as the next emerging ICU scare [ 34 ]. In our study, most P. dispersa were isolated at the neonatal ICU while two strains were isolated from adult patients admitted to the emergency outpatient department at DRH.…”

Section: Discussionmentioning

confidence: 99%

Sepsis: emerging pathogens and antimicrobial resistance in Ethiopian referral hospitals

Legese

Asrat

Swedberg

et al. 2022

Antimicrob Resist Infect Control

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Background Sepsis due to multidrug resistant (MDR) bacteria is a growing public health problem mainly in low-income countries. Methods A multicenter study was conducted between October 2019 and September 2020 at four hospitals located in central (Tikur Anbessa and Yekatit 12), southern (Hawassa) and northern (Dessie) parts of Ethiopia. A total of 1416 patients clinically investigated for sepsis were enrolled. The number of patients from Tikur Anbessa, Yekatit 12, Dessie and Hawassa hospital was 501, 298, 301 and 316, respectively. At each study site, blood culture was performed from all patients and positive cultures were characterized by their colony characteristics, gram stain and conventional biochemical tests. Each bacterial species was confirmed using Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry (MALDI TOF). Antimicrobial resistance pattern of bacteria was determined by disc diffusion. Logistic regression analysis was used to assess associations of dependent and independent variables. A p-value < 0.05 was considered as statistically significant. The data was analyzed using SPSS version 25. Results Among 1416 blood cultures performed, 40.6% yielded growth. Among these, 27.2%, 0.3% and 13.1%, were positive for pathogenic bacteria, yeast cells and possible contaminants respectively. Klebsiella pneumoniae (26.1%), Klebsiella variicola (18.1%) and E. coli (12.4%) were the most frequent. Most K. variicola were detected at Dessie (61%) and Hawassa (36.4%). Almost all Pantoea dispersa (95.2%) were isolated at Dessie. Rare isolates (0.5% or 0.2% each) included Leclercia adecarboxylata, Raoultella ornithinolytica, Stenotrophomonas maltophilia, Achromobacter xylosoxidans, Burkholderia cepacia, Kosakonia cowanii and Lelliottia amnigena. Enterobacteriaceae most often showed resistance to ampicillin (96.2%), ceftriaxone (78.3%), cefotaxime (78%), cefuroxime (78%) and ceftazidime (76.4%). MDR frequency of Enterobacteriaceae at Hawassa, Tikur Anbessa, Yekatit 12 and Dessie hospital was 95.1%, 93.2%, 87.3% and 67.7%, respectively. Carbapenem resistance was detected in 17.1% of K. pneumoniae (n = 111), 27.7% of E. cloacae (n = 22) and 58.8% of Acinetobacter baumannii (n = 34). Conclusion Diverse and emerging gram-negative bacterial etiologies of sepsis were identified. High multidrug resistance frequency was detected. Both on sepsis etiology types and MDR frequencies, substantial variation between hospitals was determined. Strategies to control MDR should be adapted to specific hospitals. Standard bacteriological services capable of monitoring emerging drug-resistant sepsis etiologies are essential for effective antimicrobial stewardship.

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Section: Discussionmentioning

confidence: 99%

Sepsis: emerging pathogens and antimicrobial resistance in Ethiopian referral hospitals

Legese

Asrat

Swedberg

et al. 2022

Antimicrob Resist Infect Control

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show abstract

“…8 Furthermore, the literature contains 3 reports on bloodstream infections caused by P dispersa in a 64-year-old man after implantation of a pacemaker, a 38-year-old woman with acute cholangitis, and a 23-year-old woman with lethal sepsis. 9 Although to our knowledge no cases of skin infections with P dispersa have been described, the literature reports cases of skin infections with P agglomerans . 4 These include a 58-year-old woman presenting with a wound infection after a penetrating plant injury and a patient with multiple skin eruptions presenting as small papules.…”

Section: Discussionmentioning

confidence: 97%

“…As P dispersa belongs to the Enterobacter species, some cases may be incorrectly identified as being caused by species of Enterobacteriaceae. 9 Common diagnostic tools, such as the MALDI Biotyper often misidentify Erwiniacea as Klebsiella species. 9 A detailed anamnesis can be helpful in these vague cases.…”

Section: Discussionmentioning

confidence: 99%

“… 9 Common diagnostic tools, such as the MALDI Biotyper often misidentify Erwiniacea as Klebsiella species. 9 A detailed anamnesis can be helpful in these vague cases. All species of Pantoea can be isolated form plant, soil, and feculent material.…”

Section: Discussionmentioning

confidence: 99%

“…The pathogenetic mechanisms of P dispersa remain unclear, and the current case report generates a range of questions as to what degree these plant pathogens can cause infections in humans. 9 …”

Section: Discussionmentioning

confidence: 99%

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Pantoea dispersa it the next emerging “monster” in our intensive care units? A case report and review of literature

Cited by 7 publications

References 15 publications

Sepsis: emerging pathogens and antimicrobial resistance in Ethiopian referral hospitals

Sepsis: emerging pathogens and antimicrobial resistance in Ethiopian referral hospitals

Folliculitis caused by Pantoea dispersa as a souvenir from a self-discovery excursion in bat caves

Work clothes as a vector for microorganisms: Accumulation, transport, and resuspension of microorganisms as demonstrated for waste collection workers

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