2011
DOI: 10.1093/ndt/gfr355
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Pain, sleep disturbance and survival in hemodialysis patients

Abstract: Pain perception while off HD may be of more importance to patients than pain during HD. The mechanisms underlying the association are unknown but may involve linkage of pain with severity of medical illness or the generation of a maladaptive cytokine response. Multicenter prospective studies of pain interventions using well-validated pain perception tools are needed to establish causal relationships. Interventions directed toward treating pain on non-HD days may improve ESRD patient survival.

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Cited by 94 publications
(85 citation statements)
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References 43 publications
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“…Both the studies have reported a significant association between poor quality of sleep and pre-dialysis serum phosphate levels. However, studies that have used the PSQI to measure sleep quality did not find any association between sleep quality and various biochemical parameters, like the present study [6,9,13,23].…”
Section: Discussioncontrasting
confidence: 62%
See 1 more Smart Citation
“…Both the studies have reported a significant association between poor quality of sleep and pre-dialysis serum phosphate levels. However, studies that have used the PSQI to measure sleep quality did not find any association between sleep quality and various biochemical parameters, like the present study [6,9,13,23].…”
Section: Discussioncontrasting
confidence: 62%
“…However, one study did not find any correlation between the mortality and poor sleep among these patients [13]. Not only the mortality but the morbidity is also important and poor quality of life has been consistently reported in patients on MHD with poor quality of sleep [4,10,12,14].…”
Section: Introductionmentioning
confidence: 93%
“…Among patients undergoing HD for end-stage renal disease (ESRD), pain is known to cause depression and a signifi cant decrease in QL (5,6). Accordingly, survival rates of those patients are affected negatively (7,8).…”
Section: Discussionmentioning
confidence: 99%
“…Beşinci yaşam bulgusu olarak kabul edilen ağrı; başetme süreci, fonksiyonel kapasite ve yaşam kalitesini olumsuz etkilemektedir (6,(12)(13)(14). Ağrıya bağlı yaşanan sosyal ilişkilerde bozulma (15,16); depresyon, anksiyete ve uyku bozuklukları gibi durumlar yaşamı daha güç hale getirmektedir (17,18). Yapılan çalışmalarda HD tedavisi alan hastaların %19,6-53,3 oranlarında ağrı deneyimlediği (19)(20)(21); başka bir çalışmada da HD hastalarının %50'sinde kronik ağrı, %55'inde şiddetli düzeyde ağrı yaşadıkları saptanmıştır (22).…”
Section: Introductionunclassified
“…HD hastalarında ağrının ne düzeyde yaşandı-ğının bilinmesinin bir sağlık profesyoneli olarak hemşirelerin planlayacakları holistik bakıma yön vereceği düşünülmektedir. Literatürde ise, HD hastalarının yaşadığı ağrıya yönelik yapılan sınırlı sayıda çalışma olduğu görülmektedir (8,10,12,18,21,22). Ülkemizde bu konu ile ilgili Er ve ark.…”
Section: Introductionunclassified