Pacemaker contact sensitivity: Clinical recognition and management

Abdallah, Hasan I.; Balsara, Rohinton K.; O'Riordan, Anna C.

doi:10.1016/0003-4975(94)90228-3

Cited by 91 publications

(48 citation statements)

References 7 publications

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“…Important, corticosteroid use can result in skin anergy and in a false-negative skin test. Allergies to various pacemaker components have been reported, including titanium (Peters et al, 1984;Yamauchi et al, 2000), polychloroparaxylene (Iguchi et al, 1997), nickel (Landwehr & van Ketel, 1983), polyurethane (Abdallah et al, 1994), epoxy (Andersen, 1979), mercury (Brun & Hunziker, 1980), cadmium (Laugier et al, 1975), chromate (Laugier et al, 1975), silicone (Raque & Goldschmidt, 1970), and cobalt (Tilsey & Rotstein, 1980). Once an allergy has been demonstrated, it is imperative that the component either be eliminated from subsequent pacing systems or be completely coated.…”

Section: Allergic Reactions To the Pacemaker Componentmentioning

confidence: 99%

Common Pacemaker Problems: Lead and Pocket Complications

Gül¹,

Kayrak²

2011

Modern Pacemakers - Present and Future

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Section: Allergic Reactions To the Pacemaker Componentmentioning

confidence: 99%

Common Pacemaker Problems: Lead and Pocket Complications

Gül¹,

Kayrak²

2011

Modern Pacemakers - Present and Future

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“…A more recent case report discussed a case of systemic dermatitis after placement of a cobalt-chromiummolybdenum implant in total knee arthroplasty (TKA); thanks to a revision TKA with a zirconium-niobium implant, pruritus resolved 3 days and eczema 2 months after surgery [16]. Apart from orthopedic implants, there are numerous case reports linking adverse immune reactions to metallic implants used in cardiovascular [17][18][19], plastic [20], and dental surgery [21][22][23]. There are more case reports concerning the use of stainless steel and cobalt alloy implants than titanium alloy implants [9].…”

Section: The Rising Potential Impact Of Metal Hypersensitivitymentioning

confidence: 99%

“…Allergic reactions to pacemakers and ICDs primarily involve localized pain or dermatitis that presents within 2 days to 24 months after implantation, with occasional reports of generalized pruritus that resolved with the removal of the pacemaker [18,119,120]. Other measures to manage hypersensitivity reactions include control of local dermatitis with topical corticosteroids, replacement of the device with one that does not contain the suspected allergen, such as customized silicone or gold-coated pacemakers [17,[121][122][123], and wrapping the device in a PTFE sheet [124][125][126][127][128].…”

Section: Intravascular Devicesmentioning

confidence: 99%

Hypersensitivity Reactions to Implanted Metal Devices: Facts and Fictions

2016

J Investig Allergol Clin Immunol

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The use of metals in the medical field has become increasingly prevalent over the past few decades. Patients find themselves being exposed to metals in a variety of ways, ranging from external exposure to instruments such as the stainless steel in surgical blades to internal exposure via medical devices being implanted in their bodies. There has been growing interest in the possibility of developing hypersensitivity reactions to constituent metals in medical implant devices, both in cutaneous and systemic forms. Hypersensitivity reactions to metals are uncommon, but they are reported and require appropriate evaluation and management, particularly if they are symptomatic. In view of the lack of consensus in the field on the appropriate steps to evaluate and manage patients with suspected metal hypersensitivity reactions, this review aims to analyze current evidence on hypersensitivity reactions to metallic implants in orthopedic surgery, endovascular surgery, obstetrics and gynecology, and dental surgery. Key words: Metal hypersensitivity. Metallic implants. ResumenEl empleo de metales dentro de la medicina ha ido aumentando de forma progresiva en las últimas décadas. Los pacientes se exponen a metales de diferentes formas desde fuentes externas, como instrumental quirúrgico como el presente en las hojas de acero de los bisturíes, hasta implantes metálicos. Como consecuencia de ello se está produciendo un interés creciente por la posibilidad de desarrollar reacciones de hipersensibilidad a metales presentes en los materiales y objetos implantados, tanto en forma de reacciones cutáneas como sistémicas. Las reacciones de hipersensibilidad a metales no son frecuentes, pero pueden desarrollarse, y por ello, requieren de un diagnóstico y tratamiento adecuado, especialmente en aquellos pacientes que desarrollen síntomas. No existe un consenso en el proceso diagnóstico ni en el tratamiento de estas reacciones en los pacientes con sospecha de alergia a metales. Esta revisión tiene por objeto actualizar la evidencia existente sobre las reacciones de hipersensibilidad a implantes metálicos en cirugía ortopédica, cirugía endovascular, cirugía obstétrica y ginecológica (OB-GYN) así como la dental. Palabras clave: Hipersensibilidad a metales. Implantes metálicos.

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“…therefore, they may cause local or systemic side effects (23). Released ions may activate the immune system, thus causing hypersensitivity reactions, tumors and other pathologies (1,2,18,30,36,37). there are limited data available about the local and systemic effects of dental implant materials made of ti and its alloys.…”

Section: Introductionmentioning

confidence: 99%