“…Epidemiological studies have shown that several factors, including lifestyle, environmental, genetic, socioeconomic, and dietary aspects, are important in the pathogenesis and progression of depression. Notably, several nutrients are reportedly associated with depression, such as vegetables (6), fruit (6), sh (7), and dietary ber (8), as well as macronutrients (proteins, carbohydrates, and fatty acids) (9), micronutrients (including vitamin B and vitamin C), and folic acid (10). Recently, several studies have focused on the relationship between depression and several fatty acids, including n-3, n-6 polyunsaturated fatty acids (PUFAs) and their ratio, whereas the relationship between this disorder and other fatty acid types, such as total fatty acids (TFAs), saturated fatty acids (SFAs), and monounsaturated fatty acids (MUFAs), has rarely been studied, and with inconsistent results.…”