Ozurdex completely located inside a crystallized lens - Results of 14 months

Başkan, Burhan; Çiçek, Ayşe; Gülhan, Ahmet; Gündoğan, Medine; Göktaş, Sertan

doi:10.1016/j.ajoc.2016.08.001

Cited by 16 publications

(19 citation statements)

References 5 publications

(8 reference statements)

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“…Poornachandra et al [11] and Clemente-Tomás et al [3] have reported no acceleration of cataract progression. Many authors [3, 4, 7, 10, 11] have found a gradual resolution of the macular edema with an intralenticular implant but Baskan et al [12] found decreasing vision and no edema improvement. Coca-Robinot et al [9] have observed very little effect of the intralenticular implant on the macular edema.…”

Section: Discussionmentioning

confidence: 99%

Accidental Intralenticular Injection of Ozurdex® for Branch Retinal Vein Occlusion: Intact Posterior Capsule and Resolution of Macular Edema

Kurt

Durukan²,

Küçükevcilioğlu

2019

Case Reports in Ophthalmological Medicine

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Purpose. We present a case of accidental intralenticular injection of Ozurdex implant in a patient with macular edema secondary to branch retinal vein occlusion. Method. A case report. Results. Intravitreal dexamethasone implant injection had been performed for macular edema due to left superior temporal vein branch occlusion to the left eye of a 78-year-old male patient. The slit-lamp examination 85 days later revealed that the dexamethasone implant was intralenticular. The best-corrected visual acuity (BCVA) was 0.16 on the Snellen chart. Cataract surgery was decided on for the cataract as there was no anterior chamber inflammation, the intraocular pressure (IOP) was normal, and the macular edema had resolved. Uneventful phacoemulsification within the bag intraocular lens placement was performed. Conclusions. Accidental intralenticular Ozurdex injection is an extremely rare complication. The surgeon must decide whether to continue to observe or intervene immediately when such a complication is encountered. Cataract surgery can be planned if the macular edema has resolved and a cataract has developed. It is important to evaluate the posterior capsule with ultrasound biomicroscopy and Scheimpflug imaging before the cataract surgery to ensure a safe surgical procedure.

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Section: Discussionmentioning

confidence: 99%

Accidental Intralenticular Injection of Ozurdex® for Branch Retinal Vein Occlusion: Intact Posterior Capsule and Resolution of Macular Edema

Kurt

Durukan²,

Küçükevcilioğlu

2019

Case Reports in Ophthalmological Medicine

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“…These four cases were all caused by intravitreal injection of dexamethasone into the crystalline lens[6-8]. In recent years, with the increase in Ozurdex injections, cases of iatrogenic lens injury have increased[9-11]. Due to the special suspending property of TA, the complication caused by TA implanted into the crystalline lens is unique.…”

Section: Discussionmentioning

confidence: 99%

Iatrogenic crystalline lens injury during intravitreal injection of triamcinolone acetonide: A report of two cases

Zheng

Liu

2019

WJCC

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BACKGROUNDIntravitreal injection has become an efficient approach for delivering drugs at therapeutic levels to the posterior segment in retinal diseases. However, the increased frequency and number of intravitreal injections have raised concerns about their side effects. As manipulation during surgery is relatively simple, details of the procedure are easily overlooked. Iatrogenic crystalline lens injury is a rare complication caused by improper manipulation during surgical procedures. We report two cases of crystalline lens injury during intravitreal injection of triamcinolone acetonide (TA) with the hope of providing an insight into this treatment.CASE SUMMARYCase 1 was a 62-year-old woman with macular edema caused by central retinal vein occlusion in her right eye, and Case 2 was a 65-year-old man with macular edema caused by branch retinal vein occlusion in his right eye. In view of the patients’ condition and economic constraints, an intravitreal injection of TA was administered. Due to inappropriate manipulation during surgery, the lens was injured. The site of lens injury and clinical manifestations were different in the two cases. Symptomatic treatment and continuous follow-up were carried out. The therapeutic effect following phacoemulsification of the cataract was satisfactory.CONCLUSIONWell-defined surgical incision under proper anesthesia, sufficient patient information and proficient anatomical skills of the physician are mandatory to prevent this rare adverse event. Careful and meticulous phacoemulsification of the cataract is suggested.

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“…[ 6 ] found the intralenticular implant to still be effective with a gradual resolution of the macular edema, Baskan et al . [ 7 ] reported no such improvement at all with further deterioration of vision.…”

Section: Discussionmentioning

confidence: 99%

Pars plana vitrectomy and re-directing a dexamethasone implant into vitreous cavity following misdirected entry into the crystalline lens

Biswas

Nandi²,

Batra³

et al. 2018

Indian J Ophthalmol

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A known diabetic patient presented with diabetic macular edema (DME) and nonproliferative diabetic retinopathy in both eyes with a vision of 6/18, N12 in the right eye and 4/60, N36 in the left eye (LE). The patient had undergone injection of dexamethasone implant in the LE which got misdirected into the crystalline lens. The patient was taken up for phacoemulsification with intraocular lens implantation along with vitrectomy and posterior vitreous detachment induction, and redirection of the dexamethasone implant into the vitreous cavity. The DME resolved over the next 3 months.

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Ozurdex completely located inside a crystallized lens - Results of 14 months

Cited by 16 publications

References 5 publications

Accidental Intralenticular Injection of Ozurdex® for Branch Retinal Vein Occlusion: Intact Posterior Capsule and Resolution of Macular Edema

Accidental Intralenticular Injection of Ozurdex® for Branch Retinal Vein Occlusion: Intact Posterior Capsule and Resolution of Macular Edema

Iatrogenic crystalline lens injury during intravitreal injection of triamcinolone acetonide: A report of two cases

Pars plana vitrectomy and re-directing a dexamethasone implant into vitreous cavity following misdirected entry into the crystalline lens

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