Oxidative damage and brain concentrations of free amino acid in chicks exposed to high ambient temperature

Chowdhury, Vishwajit S.; Tomonaga, Shozo; Ikegami, Taro; Erwan, Edi; Ito, Kaname; Cockrem, John F.; Furuse, Mitsuhiro

doi:10.1016/j.cbpa.2013.12.020

Cited by 60 publications

(43 citation statements)

References 61 publications

(58 reference statements)

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“…Heat exposure in the present condition negatively affected the growth of chicks but was not lethal. On the other hand, in layer chicks the decrease in the plasma levels of cystathionine and cystine in the present study is consistent with those reported by a previous study on layer chicks exposed to high ambient temperatures for 2 days (Chowdhury et al 2014). Among the metabolites occurring in this pathway, some are constituents of proteins (methionine and cysteine), while others are bioactive substances (taurine, hypotaurine, homocysteine, etc.)…”

Section: Discussionsupporting

confidence: 93%

Effects of high ambient temperature on plasma metabolomic profiles in chicks

Tomonaga

Okuyama

Tachibana

et al. 2017

Animal Science Journal

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Exposure to high ambient temperature is detrimental to the poultry industry. To understand the influence from a metabolic perspective, we investigated the effects of exposure to high ambient temperature on plasma low-molecular-weight metabolite levels in chicks using gas chromatography/mass spectrometry-based non-targeted metabolomic analysis. Heat exposure for 4 days suppressed growth and food intake. Of the 92 metabolites identified, the levels of 29 decreased, whereas the levels of nine increased. We performed an enrichment analysis on the identified metabolites and found 35 candidates for metabolic processes affected by heat exposure. Among them, the sulfur amino acid metabolic pathway was clearly detected and the levels of the following related metabolites were decreased: cystathionine, cysteine, cystine, homocysteine and hypotaurine. Changes in the kynurenine pathway in tryptophan metabolism, which is linked to the immune system and oxidative stress, were also observed: kynurenine and quinolinic acid levels increased, whereas nicotinamide levels decreased. These results suggest the possible involvement of various metabolic processes in heat-exposed chicks. Some of these metabolites would be important to understand the mechanism of biological responses to high ambient temperature in chicks.

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Section: Discussionsupporting

confidence: 93%

Effects of high ambient temperature on plasma metabolomic profiles in chicks

Tomonaga

Okuyama

Tachibana

et al. 2017

Animal Science Journal

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“…Elevated environmental temperatures in other colonies of seabirds nesting in artificial nests have caused harmful water loss in eggs and decreases in hatching success (Lei et al , Ropert‐Coudert et al ). In addition, extreme heat events later in the nesting season can cause heat stress for chicks in artificial nests (Sherley et al , Chowdhury et al ).…”

Section: Discussionmentioning

confidence: 99%

Environmental temperatures, artificial nests, and incubation of Cassin's auklet

et al. 2015

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Hatching success in birds is influenced by the temperature and turning rate of the egg, but our understanding of the environmental factors that effect incubation temperatures and egg turning rates in birds is limited. Especially little is known of these effects for species that nest in burrows or crevices, such as the Cassin's auklet (Ptychoramphus aleuticus). On Southeast Farallon Island, California, USA, a subset of the Cassin's auklet (hereafter auklet) population nest in artificial nest boxes. The nest boxes are above ground and made out of a single layer of plywood. Temperatures in unshaded nest boxes can increase significantly with high ambient temperatures (to >35° C). Shaded structures put on top of occupied nest boxes help mediate nest box temperatures, but the effects of elevated temperatures on auklet incubation behaviors and egg viability remain equivocal. We used egg data loggers to measure the temperatures and turning rates of auklet eggs in natural burrows, shaded nest boxes, and unshaded nest boxes on Southeast Farallon Island. Nest box (13.93 ± 1.26° C) and egg (37.43 ± 1.92° C) temperatures were highest and most variable in unshaded nest boxes. Mean hourly egg turning rate was 2.11 ± 2.02 turns/hour and turning rates were greater at night. Egg turning rates also varied with fluctuating nest and egg temperatures, being positively correlated with nest temperatures during the day and negatively correlated with egg temperatures during the night. Our results suggest that nest box design can influence incubation behaviors of breeding birds. As seasonal temperatures and the number of extreme heat events rise, understanding the impacts of temperature on auklets nesting in artificial nests can have positive implications for conservation and management of the species, such as implementing improved artificial nest box designs to prevent overheating of burrow nesting seabirds. © 2015 The Wildlife Society.

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“…The injection of D-Asp but not L-Asp released arginine vasopressin (AVP) in rats (Koyuncuoğlu et al, 1984). We have revealed the differences of L-Asp and D-Asp on stress response, feed intake and regulation of body temperature (Erwan et al, 2012(Erwan et al, , 2013a(Erwan et al, , 2013b(Erwan et al, , 2014. Further it was found that the mechanism of stress attenuating function of L-and D-Asp possibly occurs through different receptors (Erwan et al, 2012(Erwan et al, , 2014b.…”

Section: Discussionmentioning

confidence: 90%

“…Donkoh (1989) reported that continuous exposure of broilers to HT markedly affected their performance and physiological functions. In addition, HT induces quick increment of deep body temperature even in chicks (Chowdhury et al, 2012) and causes oxidative stress (Chowdhury et al, 2014). To cool down the temperature in the poultry house using fossil energy leads further increase in the environmental temperature.…”

Section: Introductionmentioning

confidence: 99%

Orally Administered D-Aspartate Depresses Rectal Temperature and Alters Plasma Triacylglycerol and Glucose Concentrations in Broiler Chicks

et al. 2017

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L-Aspartate (L-Asp), D-aspartate (D-Asp) or their chemical conjugates plays important physiological roles in regulating food intake, plasma metabolites and thermoregulation in animals. However, there are very few studies available in layers and no reports have been found in broilers. Broilers are very important commercial birds for meat production, so effects of L-or D-Asp in broilers would provide new physiological insight of this strain. Therefore, the purpose of this study was to determine the effect of oral administration of L-or D-Asp on feed intake, rectal temperature and some plasma metabolites in broiler chicks. Broiler chicks (5 days old) were orally administered with different doses (0, 3.75, 7.5 and 15 mmol/kg body weight) of L-or D-Asp. At 120 min after administration of L-or D-Asp, the blood was immediately collected through the jugular vein. The rectal temperature of chicks was measured at 30, 60 and 120 min after administration using a digital thermometer with an accuracy of ±0.1℃, by inserting the thermistor probe in the rectum to a depth of 2 cm. A repeated-measures two-way ANOVA was applied for the analysis of feed intake and rectal temperature. Plasma metabolites were statistically analyzed by one-way ANOVA and regression equations. The study showed that oral administration of both L-and D-Asp did not alter feed intake. However, D-Asp, but not L-Asp, dose-dependently decreased the rectal temperature in chicks. It was also found that DAsp increased plasma glucose and decreased triacylglycerol concentrations. The changes in plasma metabolites further indicate that D-Asp treatment modulates the energy metabolism in broiler chicks. In conclusion, D-Asp may be a beneficial nutrient not only for layers but also for broilers, since orally administered D-Asp lowered rectal temperature without reducing feed intake.

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Oxidative damage and brain concentrations of free amino acid in chicks exposed to high ambient temperature

Cited by 60 publications

References 61 publications

Effects of high ambient temperature on plasma metabolomic profiles in chicks

Effects of high ambient temperature on plasma metabolomic profiles in chicks

Environmental temperatures, artificial nests, and incubation of Cassin's auklet

Orally Administered D-Aspartate Depresses Rectal Temperature and Alters Plasma Triacylglycerol and Glucose Concentrations in Broiler Chicks

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