Ovarian fibroma — clinical and histopathological characteristics

Abstract

Twenty-three cases of ovarian fibroma, comprising 3% of all benign tumors seen over a 20-year period, were analyzed. It was unilateral in all cases affecting more commonly the left ovary (70%). Whilst a majority of cases (77%) were encountered in the reproductive age group, the tumor was rare before the second decade. Only in 13% of cases was ascitis clinically detectable. This was not influenced by the size and weight (average of 9.3 x 10.8 x 11.1 cm and 959 g, respectively) of the tumors; a smooth-surfaced tumor was, however, associated with a greater amount of peritoneal fluid. Varying degrees of calcification in some tumors are detectable on ultrasonography and occasionally on abdominal radiography. The classical Meig's Syndrome was seldom encountered. The histopathological features, diagnostic problems and management are discussed.

Ovarian Fibroma: A Clinico-pathological Study of 23 Cases with Review of Literature

“…The treatment of ovarian fibroma has always been surgical, which comprises removal of tumor followed by intraoperative frozen section [8,9]. Our study has demonstrated a very good correlation between frozen section and final histopathological diagnosis of ovarian fibroma.…”

“…In all post-menopausal women and those who have completed their family, total abdominal hysterectomy (TAH) is the treatment of choice; however, owing to benign nature of the disease, a fertility-preserving surgery with unilateral salpingo-oophorectomy in young premenopausal women can be contemplated [8,9].…”

Twisted Ovarian Fibroma Mimicking as an Ectopic Pregnancy

“…It is the commonest subtype of the sex cord-stromal tumors [2]. The mean age at diagnosis is 48 years and 90% of patients are at least 30 years old when they are diagnosed with fibroma [3]. In our case patient was 22 years old.…”

“…Occasionally large fibromas may develop a pedicle and undergo torsion causing acute abdominal symptoms as in the present case. Ascites or classic Meig's syndrome with additional hydrothorax has been found in 10% of all cases and 40% of tumors larger than 10 cm in maximum diameter [3]. Development of …”

Ovarian fibroma with a twist!

“…They can manifest with abdominal enlargement, urinary symptoms, abdominal pain and occasionally torsion. [1][2][3] Ovarian torsion is usually associated with significant pain. This lady only had minimal pain despite the large size and necrotic changes due to torsion.…”