BackgroundSince China is aging rapidly, it is necessary to evaluate the reliability, durability, and satisfaction of total knee arthroplasty (TKA) among patients over 80 years.MethodsBetween February 2009 and December 2017, 98 patients (129 knees) met the inclusion criteria and were postoperatively followed-up ≥ 3 years. TKAs included 67 unilateral TKAs and 31 bilateral TKAs. The indexes included operative time, intraoperative blood loss, tourniquet time, Knee Society Score (KSS), Visual Analogue Scale (VAS), Range of Motion (ROM), “Forgotten Joint” Scale (FJS), crutches usage and patients’ satisfaction.ResultsKSS clinical and functional scores improved significantly from preoperative mean of 33 and 27 to latest follow-up of 87 and 51, respectively (p <0.05). The VAS decreased significantly from preoperative mean scores of 8 to latest follow-up of 0 (p <0.05). The proportion of patients without crutches at last follow-up was 52%, satisfaction rate was 94% and FJS ≥ 50 was 85%. However, ROM did not improve significantly from preoperative mean 89° to latest follow-up 93° (p >0.05). The preoperative hemoglobin and survival proportions between bilateral and unilateral TKAs were not statistically different (p >0.05).ConclusionTKA was reliable, durable, and satisfied in patients older than 80 years in Chinese population.