Outcomes of patients with mucoepidermoid carcinoma of minor salivary gland in palate undergoing radical resection followed by submental flap reconstruction

Zhou, Bin; Huang, Zhuoshan; Chen, Wei‐Liang; Huang, Zheng‐Ming; Chen, Rui; Yuan, Kai‐fang; Hong, Lei; Chen, Yon-ju

doi:10.1016/j.asjsur.2021.08.039

Cited by 7 publications

(7 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The FSIF is a reliable and safe method for reconstructing Brown class II maxillary defects after cancer ablation, particularly in older patients. 16,17 Class IIIb and IIId maxillary defects were reconstructed with esPMMF or ALTF with the use of a titanium mesh for the orbital floor in patients with stage IV disease who underwent total maxillectomy through the LPM with radical neck dissection. One patient had diplopia caused by ALTF failure.…”

Section: Discussionmentioning

confidence: 99%

Maxillectomy and Flap Reconstruction of Maxillary Defects After Cancer Ablation Through the Lip-Split Parasymphyseal Mandibulotomy Approach in Patients With Advanced-Stage Maxillary Malignant Tumors

Chen

Zhou

Huang³

et al. 2023

Journal of Craniofacial Surgery

Self Cite

View full text Add to dashboard Cite

Background:The conventional approach for maxillectomy has some common and serious complications. Aims: The present study evaluated the outcomes of maxillectomy and flap reconstruction after cancer ablation using the lip-split parasymphyseal mandibulotomy (LPM) approach. Methods: Twenty-eight patients with malignant tumors, including squamous cell carcinoma, adenoid cystic carcinoma, and mucoepidermoid carcinoma, underwent maxillectomy through the LPM approach. Brown classes II and III were reconstructed with the facial-submental artery submental island flap, an extensive segmental pectoralis major myocutaneous flap, and a free anterolateral thigh flap with the use of a titanium mesh, respectively. Results: All proximal margin frozen section specimens showed negative surgical margins. Anterolateral thigh flap failure occurred in 1 patient, whereas ophthalmic and mandibulotomy complications developed in 4 and 7 patients, respectively. In all, 84.6% of the patients had satisfactory or excellent lip esthetic results. Of the patients, 57.1% were alive with no evidence of disease, whereas 28.6% were alive with disease and 14.3% died of local recurrence or distant metastasis. No significant survival difference was evident among the squamous cell carcinoma, adenoid cystic carcinoma, and mucoepidermoid carcinoma groups.Conclusions: The LPM approach can provide good surgical access, facilitating maxillectomy in advanced-stage malignant tumors with minimal morbidity. Facial-submental artery submental island flap and anterolateral thigh flap or extensive segmental pectoralis major myocutaneous flap with a titanium mesh are ideal techniques for reconstructing Brown classes II and III defects, respectively.

show abstract

Section: Discussionmentioning

confidence: 99%

Maxillectomy and Flap Reconstruction of Maxillary Defects After Cancer Ablation Through the Lip-Split Parasymphyseal Mandibulotomy Approach in Patients With Advanced-Stage Maxillary Malignant Tumors

Chen

Zhou

Huang³

et al. 2023

Journal of Craniofacial Surgery

Self Cite

View full text Add to dashboard Cite

show abstract

“…Commonly used flaps include the radial forearm and anterolateral thigh flaps [14]. However, local and pedicle flaps play important roles in oral and maxillofacial reconstruction, even in the era of free flaps, such as supraclavicular artery island flaps [15,16], pectoralis major myocutaneous flaps [13,17], and FSAIF [9,[18][19][20].…”

Section: Discussionmentioning

confidence: 99%

Facial-submental island flap for reconstruction of hemitongue defects in young, middle-aged and elderly patients with early and middle stage oral tongue squamous cell carcinoma

et al. 2022

View full text Add to dashboard Cite

Background This study evaluated the outcomes of facial-submental artery island flap (FSAIF) for reconstruction of the hemitongue following cancer ablation in patients with early and middle-stage oral tongue squamous cell carcinoma (OTSCC). Methods In total, 122 patients with early and middle-stage OTSCC were divided into young, middle-aged, and elderly groups. The Adult Comorbidity Evaluation-27 (ACE-27) index was used to determine the presence of comorbidities. The patients underwent surgical treatment with hemiglossectomy, neck dissection, and hemitongue reconstruction using FSAIF. In addition, stage I (n = 15) and II (n = 69) patients underwent ipsilateral selective neck dissection, whereas those with stage III (n = 38) underwent radical neck dissection. Six patients with T3N1 disease also underwent cobalt-60 adjuvant radiotherapy. Results Young and elderly patients exhibited significant differences in comorbidities, as assessed by the ACE-27 (p < .05). The skin paddles in the young, middle-aged, and elderly patients were 3 × 9 to 4 × 12 cm, 3 × 11 to 4 × 12, and 3 × 10 to 5 × 13 cm in size, respectively. FSAIF failure occurred in four patients (success rate: 96.7%). No significant differences were observed in the skin paddle of the flap or rate of flap failure among the age groups (p > .05). Clavien-Dindo grades I, II, IIIa, IIIb, Iva, and IVb were assigned to 7.1, 36.1, 38.5, 9.8, 4.1, and 4.1% of the patients, respectively, with significant differences seen between the young and elderly patients (p < .05). In total, 52.5% of patients could eat normally, whereas 32.8% required a soft diet. Furthermore, 53.3 and 33.6% of patients achieved normal and intelligible speech, respectively. The aesthetic results were rated as excellent and good in 32.8 and 58.2% of patients, respectively. In total, 68.0% of the patients were alive and exhibited no evidence of disease, while 19.7% were alive with active disease. In addition, 12.3% of patients with stage III OTSCC died due to local recurrence or distant metastases. No differences in swallowing, speech, aesthetic, or survival outcomes were observed among the groups. Conclusions FSAIF is a simple, safe, and reliable method for reconstructing hemitongue defects following cancer ablation in young, middle-aged, and elderly patients with early and middle-stage OTSCC.

show abstract

“…The treatment of high-grade tumors is usually radical excision in combination with postoperative radiotherapy. lymph node dissection is indicated for high grade T2_T4 and T4b tumors [2]. If there is a bone erosion, removal of the involving bone is indicated [9].…”

Section: Discussionmentioning

confidence: 99%

“…Mucoepidermoid carcinoma (MEC) is the most common malignant salivary gland neoplasm in the oral cavity, occurring mainly in the major salivary glands. The most common pathological type for the salivary gland tumors of the head and neck was mucoepidermoid carcinoma accounting for 40% followed by adenoid cystic carcinoma 31% [1,2]. About 5% of these tumors occur in patients younger than 18-yearold with women mostly affected [1,3].…”

Section: Introductionmentioning

confidence: 99%

Mucoepidermoid Carcinoma of the Palate: A Case Report and Literature Review

Bouchra¹

2022

J Clin Stud Rev Rep

View full text Add to dashboard Cite

Mucoepidermoid carcinoma (MEC) is the epithelial salivary gland neoplasm of the oral cavity. The most common pathological type for the salivary gland tumors of the head and neck was mucoepidermoid carcinoma. In our work, we report a case of mucoepidermoid carcinoma observed in a 50-year-old man. Clinically, he presented the ulcer-budding tumor of the soft palate, movable relative to the deep plan measuring 2,5 cm. The diagnosis was based on clinical, radiological and pathological arguments. Complete surgical excision is the treatment of choice in combination with postoperative radiotherapy and chemotherapy

show abstract

Outcomes of patients with mucoepidermoid carcinoma of minor salivary gland in palate undergoing radical resection followed by submental flap reconstruction

Cited by 7 publications

References 20 publications

Maxillectomy and Flap Reconstruction of Maxillary Defects After Cancer Ablation Through the Lip-Split Parasymphyseal Mandibulotomy Approach in Patients With Advanced-Stage Maxillary Malignant Tumors

Maxillectomy and Flap Reconstruction of Maxillary Defects After Cancer Ablation Through the Lip-Split Parasymphyseal Mandibulotomy Approach in Patients With Advanced-Stage Maxillary Malignant Tumors

Facial-submental island flap for reconstruction of hemitongue defects in young, middle-aged and elderly patients with early and middle stage oral tongue squamous cell carcinoma

Mucoepidermoid Carcinoma of the Palate: A Case Report and Literature Review

Contact Info

Product

Resources

About