Outcomes and prognosis in systemic lupus erythematosus

Tarasova, I.A.; Иванова, М М

doi:10.14412/1995-4484-2003-770

Cited by 2 publications

(1 citation statement)

References 36 publications

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“…Заболевание в значительной степени негативно влияет на качество жизни (КЖ) пациентов, которым нередко приходится полагаться на помощь близких при выполнении даже незначительных повседневных дел, многие теряют трудоспособность и вынуждены оставить привычную работу, часто менять планы в зависимости от состояния здоровья [8][9][10].…”

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Parameters of the internal picture of the disease and quality of life in patients with systemic lupus erythematosus

Ялтонский

Абросимов

Андрушкевич

et al. 2020

Sovremennaâ revmatologiâ

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Objective: to analyze the structural features of the internal picture of the disease (IPD in patients with systemic lupus erythematosus (SLE) and its ratio with quality of life (QOL) as an indicator of adaptation to the disease.Patients and methods. The investigation enrolled 51 patients with SLE. Comparison groups included patients differing in the psychological parameter – the perception of the existing disease as a threat to life and health: Group 1 (n=17) regarded their disease as a moderate threat to life and well-being; Group 2 (n=34) considered it as a severe threat.Results and discussion. Comparative analysis of the cognitive level of IPD revealed statistically significant differences between the patients of Groups 1 and 2 in the following scales: «course of the disease» (p<0.001), «personal control» (p<0.001), «treatment control» (p<0.001), «understandability of the disease» (p<0.001), «emotional response to the disease» (p<0.005), and «overall level of disease threats» (p<0.001). It turned out that Group 1 patients better understood the features of the course and manifestation of the disease, were more confident in the efficiency and importance of the treatment prescribed, as well as in their own capabilities to improve their health status. Group 2 patients were more inclined to try to cope with the existing negative experiences, by avoiding the problem.Conclusion. IPD can be different in patients with SLE. The perception of illness as a severe threat negatively affects the efficiency of therapy, mental well-being, social activity, and ultimately QOL. The findings can be used to develop programs for psychological support of patients with rheumatic diseases, in particular those with SLE.

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Parameters of the internal picture of the disease and quality of life in patients with systemic lupus erythematosus

Ялтонский

Абросимов

Андрушкевич

et al. 2020

Sovremennaâ revmatologiâ

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Modern clinical and epidemiological characteristic of systemic lupus erythematosus based on the data of the territorial registry

et al. 2017

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Systemic lupus erythematosus (SLE) is a severe rheumatic disease characterized by polysymptomatic clinical picture. At the present stage, there are no updated epidemiological data due to the low prevalence of the disease. The aim of the study was to examine the current clinical and epidemiological characteristics of patients with systemic lupus erythematosus based on the information contained in the territorial register, analysis of occurrence and symptoms at the early stage of the disease. This study demonstrated the epidemiological and clinical characteristics of SLE from the analysis of 107 cases during the period from 2011 to 2013 and retrospective analysis of the cases for 1980-2013. The epidemiological situation was evaluated based on extensive and intensive indicators using statistical software license. The current SLE prevalence was estimated at 5,59 per 100 000 population in 2013, the incidence between 1994 and 2003 at 0,29 per 100 000 population and between 2004 and 2013 at 0,49, with the peak in 2010 up to 1,35 per 100 000 population. The average absolute growth and growth rate of SLE in the first decade was 0,05% and 0,24%, in the second decade 0,001% and 0,006% respectively, with the female to male ratio being 9:1, mean age of the patients 37,62±11,65 years), and ethnic composition of 87 Slavs and 15 Crimean Tatars. The most common symptoms at the early (polyarthritis, fever, dermatitis) and advanced (polyarthritis, Raynaud's syndrome, carditis, myalgia) stages differed from those specified by American College of Rheumatology (1997). The difference between early and late symptoms of SLE was documented . Based on the data obtained, the division of the disease into clinical subtypes (phenotypes) is proposed.

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Outcomes and prognosis in systemic lupus erythematosus

Cited by 2 publications

References 36 publications

Parameters of the internal picture of the disease and quality of life in patients with systemic lupus erythematosus

Parameters of the internal picture of the disease and quality of life in patients with systemic lupus erythematosus

Modern clinical and epidemiological characteristic of systemic lupus erythematosus based on the data of the territorial registry

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