“…AD involves a type 2 cytokine inflammatory response with the activation of IL-4 and IL-13 [ 57 , 110 ]. Actual treatments for AD are topical moisturizers, corticosteroids, calcineurin inhibitor, phototherapy, and systemic immunotherapy [ 113 , 114 , 115 , 116 , 117 , 118 , 120 ]. All of these treatments have limited short-term efficacy, significant or even limiting side effects when administered for long periods of time, or are prohibitively expensive [ 113 , 114 , 115 , 116 , 117 , 118 , 120 ].…”