Ouratea genus: chemical and pharmacological aspects

Fidelis, Queli Cristina; Ribeiro, Tereza Auxiliadora Nascimento; Araújo, Marcelo Francisco de; Carvalho, Mário Geraldo de

doi:10.1590/0102-695x20142413361

Cited by 31 publications

(20 citation statements)

References 69 publications

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“…Leaves of O. spectabilis are used as stomachic and vermifuge, as well as for the treatment of gastric distress. Leaf infusions of O. parviflora have long been prescribed for the treatment of inflammation-related diseases such as rheumatism, sprains and arthritic disorders, and further skin diseases [4,20,21]. In this study O. fieldingiana oil gave positive results in ear edema tests confirming the use of the plant for skin diseases, similarly to other oils of this study.…”

Section: Discussionsupporting

confidence: 77%

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Fatty Acid Profile and Anti-Inflammatory Activity of Fixed Plant Oils

Morais

Nascimento

Silva

et al. 2017

Acta Scientiae. Vet.

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Background: Many seed oils have been used as anti-inflammatory agents, administred by ingestion or topical application in traditional medicine. The objective of this research was to perform a chemical analysis of fatty profile and a pharmacological study through a topical experiment of TPA-induced ear edema test and an internal assay - acetic acid-induced vascular permeability in Swiss mice of some fixed oils popularly used for inflammatory problems, trying to confirm their action.Materials, Methods & Results: Fixed lipids of Ouratea fieldingiana (batiputá), Caryocar coreaceum (pequi), Annacardium occidentale (cashew-nuts), Cocos nucifera (coco-da-bahia), Byrsonima crassifolia (murici) e Elaeis guineenses (palm) were selected for the identification of fatty acids profile by gas chromatography coupled to mass spectrometry (GC/MS) analysis and evaluation of anti-inflammatory activity by TPA-induced ear edema test and acetic acid-induced vascular permeability in Swiss male mice. The oils were purchased in local markets or extracted in Soxhlet apparatus with hexane. The oils of cashew nut, murici fruit, and pequi nut presented a high percentage of unsaturated fatty acids (81.80, 74.46 and 60.72 %, respectively). In the oils of batiputá and murici, linoleic acid was the main unsaturated fatty acid (45.06% and 74.66%, respectively) and oleic acid was main constituent in cashew nut, pequi and palm seed oils. Batiputá and palm oils exibit approximately equivalent content of saturated and unsaturated fatty acid and coconut oil more saturated fatty acids (80.72%) with predominance of lauric acid. The result of TPA-induced ear edema test revealed that all oils presented similar anti-inflammatory activity. In the acetic acid-induced vascular permeability model, the oil of O. fieldingiana was the only one who showed anti-inflammatory activity, while C. coreaceum and B. crassifolia oils showed pro-inflammatory activities. The presence of phenols and flavonoids was evaluated in the O. fieldingiana oil by spectrophometric methods.Discussion: All the oils showed anti-inflammatory action in the TPA-induced ear edema, probably the action of unsaturated fatty acids was more important in topical application, nevertheless in internal inflammation process the presence of antioxidant phenolic compounds could contribute to the higher activity of the oil from O. fieldingiana. The effect of linoleic and oleic acids was demonstrated on the inflammatory response of the skin during the healing process and on the release of pro-inflammatory cytokines by rat neutrophils in a prevoius study using sunflower oil. Both oleic and linoleic acids increased the wound healing tissue mass. The total protein and DNA contents of the wounds were increased by the treatment with linoleic acid. This pro-inflammatory effect of oleic and linoleic acids may contribute to the wound healing process. In this study with six plant oils, some of them have higher content in linoleic acid and others oleic acid is the major constituent so the antiinflamatory action on ear edema can be associated to these two unsaturaded fatty acids mechanism of action. In the internal model, probably other chemical constituents revealed in Ouratea fieldingiana as phenols, condensed tannins, flavones and flavanones, could contribute to the anti-inflammatory activity.

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Section: Discussionsupporting

confidence: 77%

“…The 12-O-tetradecanoylphorbol 13-acetate (TPA) 4 is an irritant used in cutaneous inflammation model in mice ears. The topical application of TPA induces inflammation and hyperproliferative responses (when used chronically) in animals, resembling in many respects the signs of some skin diseases such as psoriasis [12].…”

Section: Tpa-induced Ear Edema Testmentioning

confidence: 99%

Fatty Acid Profile and Anti-Inflammatory Activity of Fixed Plant Oils

Morais

Nascimento

Silva

et al. 2017

Acta Scientiae. Vet.

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“…Up to now, about 111 constituents, including flavonoids, anthranoids, triterpens, steroids, fatty acids and some others have been identified in the oil. These information were documented by Makhafola and Eloff (2012), Voegele (2013) and Fidelis et al (2014) as they stated that seeds of Ochna serrulata contain about 31% oil.…”

Section: Introductionmentioning

confidence: 93%

Effect of Some Fertilization Treatments on Growth and Chemical Composition of Ochna Serrulata (Hochst.) Walp. Shrubs

El-Fouly

2015

Scient. J. of Flowers and Ornament. Plants

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“…3. Intensive phytochemical studies have revealed the Ochnaceae family as an important source of biflavonoids which is well represented in some genera such as Lophira, Luxemburgia, Ochna, Ouratea than others [19,20].…”

Section: Phytochemicals Studiesmentioning

confidence: 99%

A Review on Yellow Peeling Plane (Brackenridgea zanguebarica Oliv.): A Critically Endangered Endemic Plant Species

Tiawoun

Tshisikhawe

Gwata

2018

ARRB

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Brackenridgea zanguebarica Oliv. is among the most popular and frequently used tree species in Vhembe District, Limpopo Province of South Africa. However, the increasing illegal overexploitation coupled with the reproductive inefficiency have caused a severe depletion of this plant population bringing the species on the verge of extinction. B. zanguebarica, commonly known as "yellow peeling plane" and locally known as "Mutavhatsindi" is an important tree usually used both for medicinal and magico religious purposes in the region. This most sought after species is a critically endangered species with its distribution in South Africa restricted to Thengwe village in Vhembe District municipality. It is therefore crucial to develop various propagation protocols in order to increase the availability of this species and expand its distribution area in the region. Despite the Tiawoun et al.; ARRB, 29(5): 1-13, 2018; Article no.ARRB.44847 2 risk of extinction and the multipurpose uses, there is a lack of scientific knowledge about many aspects of this plant species. This study revealed that mostly bark is being collected for medicinal use. The aim of the current study was to compile up-to-date scientific information about this critically endangered plant species to promote its conservation. In view of the importance of conservation of such a red-listed plant species, the present review focused on various aspects necessary in strengthening its conservation strategies. Review Article

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Ouratea genus: chemical and pharmacological aspects

Cited by 31 publications

References 69 publications

Fatty Acid Profile and Anti-Inflammatory Activity of Fixed Plant Oils

Fatty Acid Profile and Anti-Inflammatory Activity of Fixed Plant Oils

Effect of Some Fertilization Treatments on Growth and Chemical Composition of Ochna Serrulata (Hochst.) Walp. Shrubs

A Review on Yellow Peeling Plane (Brackenridgea zanguebarica Oliv.): A Critically Endangered Endemic Plant Species

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