Osteoprotegerin levels in peri‐implant crevicular fluid

Arikan, Fatih; Buduneli, Nurcan; Kütükçüler, Necil

doi:10.1111/j.1600-0501.2007.01463.x

Cited by 48 publications

(50 citation statements)

References 47 publications

(56 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Similar to findings in GCF obtained from sites with periodontitis (Belibasakis and Bostanci 2012), there is increasing evidence showing the association of the receptor activator of nuclear factor kappaB ligand (RANKL) -osteoprotegerin (OPG) system with the occurrence and severity of periimplantitis (Arikan et al 2008;Arikan et al 2011;Sarlati et al 2010;Guncu et al 2012;Duarte et al 2009a;Duarte et al 2009b;Rakic et al 2013). A few studies looking into other markers of bone metabolism, such as osteocalcin, reported that these are higher in PICF from peri-implant mucositis compared to healthy sites, whereas no differences were observed between periimplatitis and either mucositis or health.…”

supporting

confidence: 55%

Peri-Implant Infections of Oral Biofilm Etiology

Belibasakis

Charalampakis

Bostancı

et al. 2014

Advances in Experimental Medicine and Biology

105

View full text Add to dashboard Cite

Biofilms are complex microbial communities that grow on various surfaces in nature. The oral micobiota tend to form polymicrobial biofilms, particularly on the hard mineralized surfaces of teeth, which may impact on oral health and disease. They can cause inflammation of the adjacent tooth-supporting (periodontal) tissues, leading to destructive periodontal disease and tooth loss. The emergence of osseointegrated dental implants as a restorative treatment option for replacing missing teeth has also brought along new artificial surfaces within the oral cavity, on which oral bacteria can form biofilms. As in the case of natural teeth, biofilms on implant surfaces may also trigger infection and cause inflammatory destruction of the peri-implant tissue (i.e. peri-implantitis). While there are strong similarities in the composition of the mixed microbial flora between periodontal and peri-implant infections, there are also a few distinctive differences. The immunological events underlying the pathogenesis of peri-implant infections are qualitatively similar, yet more extensive, compared to periodontal infections, resulting in a faster progression of tissue destruction. This chapter summarizes the current knowledge on the microbiology and immunology of peri-implant infections, including findings from the peri-implant crevicular fluid, the inflammatory exudate of the peri-implant tissue. Moreover, it discusses the diagnosis and current approaches for the treatment of oral infections.

show abstract

supporting

confidence: 55%

Peri-Implant Infections of Oral Biofilm Etiology

Belibasakis

Charalampakis

Bostancı

et al. 2014

Advances in Experimental Medicine and Biology

105

View full text Add to dashboard Cite

show abstract

“…Lappin et al (2007) reported decreased serum OPG levels and greater soluble receptor activator of nuclear-factor kappa B ligand (sRANKL) sRANKL/OPG ratios in smoker patients in the maintenance program than the non-smoker counterparts. Negative correlation between pack-years and total OPG amount in peri-implant crevicular fluid was detected in clinically healthy implants (Arıkan et al 2008). Our recent finding of higher sRANKL, lower OPG concentrations in saliva of untreated/treated smokers than non-smokers confirmed these findings.…”

Section: Introductionsupporting

confidence: 79%

Effects of Tobacco Smoking on Chronic Periodontitis and Periodontal Treatment

Buduneli¹

2012

Pathogenesis and Treatment of Periodontitis

Self Cite

View full text Add to dashboard Cite

“…This result, however, was not correlated with clinical signs. At the same time, Arikan et al (2008Arikan et al ( , 2011 observed that OPG is a potential marker to assess implant conditions and its local levels may help to distinguish diseased and healthy implants. Another marker that could represent the destruction of tissues-pyridinoline cross-linked carboxyterminaltelopeptide of type I collagen (ICTP)-has been evaluated in previous clinical studies.…”

Section: Discussionmentioning

confidence: 99%