Osteoporosis and mortality

Leboime, Ariane; Confavreux, Cyrille; Mehsen, Nadia; Paccou, Julien; David, Claire; Roux, Christian

doi:10.1016/s1297-319x(10)70004-x

Cited by 122 publications

(72 citation statements)

References 31 publications

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“…These percentages are very similar to a report on hip fractures based on a US nationwide in-patient sample from the year 2000 to 2011 [6]. Osteoporosis is concomitant to increased mortality, in particular for fractures of the hip and spine, but also for other major fractures [20][21][22][23]. However, the cause of death is rarely the fracture itself but a related chronic illness [24,25].…”

Section: Discussionsupporting

confidence: 82%

The impact of osteoporotic fractures compared with other health conditions in older adults living in Virginia, United States

et al. 2016

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Section: Discussionsupporting

confidence: 82%

The impact of osteoporotic fractures compared with other health conditions in older adults living in Virginia, United States

et al. 2016

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“…Due to its association with increased risk of fracture, osteoporosis is classified as a public health problem [3]. Osteoporotic fractures, in particular spine and hip fractures, have a high morbidity and mortality and generate immense financial cost [4][5][6]. Therefore, different methods have been established to identify patients at high risk of osteoporotic fractures and to initiate appropriate therapy.…”

mentioning

confidence: 99%

Converted Lumbar BMD Values Derived from Sagittal Reformations of Contrast-Enhanced MDCT Predict Incidental Osteoporotic Vertebral Fractures

et al. 2012

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We obtained baseline and follow-up bone mineral density (BMD) values of the lumbar spine from sagittal reformations of routine abdominal contrast-enhanced multidetector computed tomography (MDCT) using a reference phantom and assessed their performance in differentiating patients with no, existing, and incidental osteoporotic fractures of the spine. A MDCT-to-QCT (quantitative computed tomography) conversion equation for lumbar BMD measurements was developed by using 15 postmenopausal women (63 ± 12 years), who underwent standard lumbar QCT (L1-L3) and afterward routine abdominal contrast-enhanced MDCT. Sagittal reformations were used for corresponding lumbar BMD measurements. The MDCT-to-QCT conversion equation was applied to baseline and follow-up routine abdominal contrast-enhanced MDCT scans of 149 postmenopausal women (63 ± 10 years). Their vertebral fracture status (no, existing, or incidental osteoporotic fracture) was assessed in the sagittal reformations. A correlation coefficient of r = 0.914 (p < 0.001) was calculated for the BMD values of MDCT and standard QCT with the conversion equation BMD(QCT) = 0.695 × BMD(MDCT) - 7.9 mg/mL. Mean follow-up time of the 149 patients was 20 ± 12 months. Fifteen patients (10.1 %) had an existing osteoporotic vertebral fracture at baseline. Incidental osteoporotic vertebral fractures were diagnosed in 13 patients (8.7 %). Patients with existing and incidental fractures showed significantly (p < 0.05) lower converted BMD values (averaged over L1-L3) than patients without fracture at baseline and at follow-up. In this longitudinal study, BMD values of the lumbar spine derived from sagittal reformations of routine abdominal contrast-enhanced MDCT predicted incidental osteoporotic vertebral fractures.

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“…Accordingly, characterizing the burden of an illness pertaining to health care resources utilization plays a vital role in optimal management of constrained resources [41]. Moreover, it has been proposed that optimal osteoporosis management may affect the risk of death [42]. Hence, it is imperative to optimize health status preoperatively and prevent postoperative complications in the elderly in the hope of reducing the mortality and costs of osteoporosis-related fractures.…”

Section: Discussionmentioning

confidence: 99%

The mortality and direct medical costs of osteoporotic fractures among postmenopausal women in Taiwan

et al. 2015

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Osteoporosis and mortality

Cited by 122 publications

References 31 publications

The impact of osteoporotic fractures compared with other health conditions in older adults living in Virginia, United States

The impact of osteoporotic fractures compared with other health conditions in older adults living in Virginia, United States

Converted Lumbar BMD Values Derived from Sagittal Reformations of Contrast-Enhanced MDCT Predict Incidental Osteoporotic Vertebral Fractures

The mortality and direct medical costs of osteoporotic fractures among postmenopausal women in Taiwan

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