The mortality and direct medical costs of osteoporotic fractures among postmenopausal women in Taiwan

Chang, Chih Yu; Tang, Chao Hsiun; Chen, K.-C.; Huang, Kuo‐How

doi:10.1007/s00198-015-3238-3

Cited by 34 publications

(22 citation statements)

References 41 publications

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“…Osteoporotic hip fractures are an important cause of morbidity and mortality in the older adult population . These patients are usually frail and are at high risk of perioperative complications . One of these important complications is acute upper gastrointestinal ulceration and its related complications.…”

Section: Baseline Characteristics Of Patients With Acute Ugib and Conmentioning

confidence: 99%

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Upper gastrointestinal bleeding in neck of femur fracture patients: a single tertiary centre experience

Liu

Gupta

Hay

et al. 2018

Internal Medicine Journal

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This study aimed to identify the incidence of perioperative acute upper gastrointestinal bleeding (UGIB) in our hip fracture patients; to evaluate the characteristics, management and clinical outcomes of these patients; and to explore risk factors and protective factors. Of the 1691 consecutive patients admitted for surgical management of hip fractures, 11 (0.65%) had UGIB and a further four patients for each case were selected as controls for evaluation of risk factors and protective factors. Pre-existing peptic ulcer disease was identified as a risk factor for acute UGIB (odds ratio 7.9; 95% confidence interval: 1.1-54.9). This study reported a very low incidence of UGIB in hip fracture patients. Despite being a high-risk population, timely endoscopic evaluation can be safely undertaken to optimise patient outcome. When risk factors such as history of peptic ulcer disease are present, additional precaution including gastro-protective agent and nutritional support should be undertaken.

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Section: Baseline Characteristics Of Patients With Acute Ugib and Conmentioning

confidence: 99%

“…perioperative complications. 2,3 One of these important complications is acute upper gastrointestinal ulceration and its related complications. It results in surgical delay, increased length of stay (LOS), 4,5 and represents a significant risk factor for mortality at 30 days and 1 year.…”

mentioning

confidence: 99%

Upper gastrointestinal bleeding in neck of femur fracture patients: a single tertiary centre experience

Liu

Gupta

Hay

et al. 2018

Internal Medicine Journal

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“… 1 - 3 The costs of diagnosing and treating osteoporosis in both developed and developing countries are very high. 4 , 5 Currently, the diagnosis of primary osteoporosis without fragility fracture is based on bone mineral density (BMD), which can be measured conveniently and non-invasively by dual-energy X-ray absorptiometry (DXA). Not all physicians, however, have access to this equipment.…”

Section: Introductionmentioning

confidence: 99%

“…Despite improvements in treatment, osteoporotic fractures remain difficult to treat. 5 , 6 They may take a long time to heal 7 and are associated with high complication rates and adverse outcomes. 8 , 9 The surgical treatment of fractures around the knee in elderly patients and those with osteoporosis remains problematic.…”

Section: Introductionmentioning

confidence: 99%

Radiographic predictors for bone mineral loss

Sun

et al. 2018

Bone & Joint Research

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ObjectivesResearchers continue to seek easier ways to evaluate the quality of bone and screen for osteoporosis and osteopenia. Until recently, radiographic images of various parts of the body, except the distal femur, have been reappraised in the light of dual-energy X-ray absorptiometry (DXA) findings. The incidence of osteoporotic fractures around the knee joint in the elderly continues to increase. The aim of this study was to propose two new radiographic parameters of the distal femur for the assessment of bone quality.MethodsAnteroposterior radiographs of the knee and bone mineral density (BMD) and T-scores from DXA scans of 361 healthy patients were prospectively analyzed. The mean cortical bone thickness (CBTavg) and the distal femoral cortex index (DFCI) were the two parameters that were proposed and measured. Intra- and interobserver reliabilities were assessed. Correlations between the BMD and T-score and these parameters were investigated and their value in the diagnosis of osteoporosis and osteopenia was evaluated.ResultsThe DFCI, as a ratio, had higher reliability than the CBTavg. Both showed significant correlation with BMD and T-score. When compared with DFCI, CBTavg showed better correlation and was better for predicting osteoporosis and osteopenia.ConclusionThe CBTavg and DFCI are simple and reliable screening tools for the prediction of osteoporosis and osteopenia. The CBTavg is more accurate but the DFCI is easier to use in clinical practice.Cite this article: Q-F. He, H. Sun, L-Y. Shu, Y. Zhu, X-T. Xie, Y. Zhan, C-F. Luo. Radiographic predictors for bone mineral loss: Cortical thickness and index of the distal femur. Bone Joint Res 2018;7:468–475. DOI: 10.1302/2046-3758.77.BJR-2017-0332.R1.

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“…Several studies have shown that osteoporotic vertebral fractures and hip fractures are associated with excess mortality [2][3][4][5] and often lead to deterioration in quality of life, impaired level of function, increased residential needs, and, in some cases, permanent stay at a nursing home [6][7][8][9].…”

Section: Introductionmentioning

confidence: 99%

Compliance and persistence with treatment with parathyroid hormone for osteoporosis. A Danish national register-based cohort study

2015

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The mortality and direct medical costs of osteoporotic fractures among postmenopausal women in Taiwan

Abstract: The present study confirmed an excess mortality and higher direct medical costs associated with osteoporotic fractures. Moreover, hip fractures constituted the most severe and expensive complication of osteoporosis among fracture types.

Cited by 34 publications

References 41 publications

Upper gastrointestinal bleeding in neck of femur fracture patients: a single tertiary centre experience

Upper gastrointestinal bleeding in neck of femur fracture patients: a single tertiary centre experience

Radiographic predictors for bone mineral loss

Compliance and persistence with treatment with parathyroid hormone for osteoporosis. A Danish national register-based cohort study

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