Histopathology - Reviews and Recent Advances 2012
DOI: 10.5772/51030
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Ossifying Fibromas of the Craniofacial Skeleton

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Cited by 15 publications
(10 citation statements)
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References 32 publications
(62 reference statements)
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“…In addition, it is necessary to eliminate local etiological factors, such as bacterial plaque and calculus (Kale et al, 2014). Surgical excision of the lesion becomes the treatment of choice in these cases due to the significant reduction of recurrences, when compared to conservative treatment through enucleation and removal of the periosteal tissue adjacent to the lesion (Emerson et al, 2012) .As in the case described, marginal resection of the injury with safety margins was the treatment of choice for this case, with an extremely satisfactory evolution (Carvalho et al, 2012;Kharsan et al, 2018) .However, radical treatment can cause severe sequelae to patients, requiring more procedures so that functional and aesthetic rehabilitation is achieved, the that was not necessary in the reported case (Emerson et al, 2012).…”
Section: Discussionmentioning
confidence: 83%
“…In addition, it is necessary to eliminate local etiological factors, such as bacterial plaque and calculus (Kale et al, 2014). Surgical excision of the lesion becomes the treatment of choice in these cases due to the significant reduction of recurrences, when compared to conservative treatment through enucleation and removal of the periosteal tissue adjacent to the lesion (Emerson et al, 2012) .As in the case described, marginal resection of the injury with safety margins was the treatment of choice for this case, with an extremely satisfactory evolution (Carvalho et al, 2012;Kharsan et al, 2018) .However, radical treatment can cause severe sequelae to patients, requiring more procedures so that functional and aesthetic rehabilitation is achieved, the that was not necessary in the reported case (Emerson et al, 2012).…”
Section: Discussionmentioning
confidence: 83%
“…Histologically, osteofibromas are characterized by dense fibroblastic stroma resembling disordered granulation tissue with isomorphic fibroblasts transforming into osteoblasts. Relatively regular spicules and trabeculae of bone rimmed by osteoblasts may be formed in a moderately vascularized fibro-osseous stroma (Carvalho et al, 2012;Morse et al, 1988). Osteofibroma can be histopathologically distinguished from fibrous dysplasia, osteoma and osteosarcoma (Kodaira et al, 2010;Morse et al, 1988).…”
Section: Resultsmentioning
confidence: 99%
“…The recurrence rates after resection range from 30% to 56%. This may be due to the infiltrative nature of the tumor borders after an incomplete excision of the tumor, rather than any intrinsic biological properties of the tumor [ 6 ]. Despite the aggressive nature and high rate of recurrence, malignant transformation has not been reported.…”
Section: Discussionmentioning
confidence: 99%