“…5,17,27,29 Today, both materials are widely accepted; however, there is a preferential tendency for titanium alloy owing to its attractive mechanical properties (see Table 1), such as Young's modulus closer to the intact diaphyseal cortical bone, higher fatigue strength and yield strength, and the fact that it is biocompatible and shows less magnetic resonance imaging interference than that observed for stainless steel implants. 3,14,[29][30][31][32] Today, the increased pref-erence for limited reaming or "ream-to-fit" techniques allowed the adoption of anatomically smaller diameter nails, which in static locked mode provide a sufficiently large interfragmentary motion that favors callus development. 10,21,32 Despite its effectiveness and reliability as a stabilization system, intramedullary nailing is still subject to constant upgrades that aim to improve the time and quality of the callus formation, as described below.…”