Orofacial Edema and Facial Paralysis

Yu, Sheng-nan; Qin, Li

doi:10.1097/rhu.0000000000001339

Cited by 4 publications

(2 citation statements)

References 2 publications

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“…Thirty-eight cases were identified in the literature. 11–35 These cases were reviewed and added to the above 9 patients in the case series. There were a total of 47 patients between the systematic review and case series with PPOFG.…”

Section: Resultsmentioning

confidence: 99%

“…Characteristics of the patients can be found in Table 1. Of the 47 patients in the case series and systematic review, 33 (70.2%) had medical history reported: 15 (15/34; 45.5%) were otherwise healthy, 14–16,20,26,30–32,35 6 (18.2%) had diabetes, 11,14,19,21,31 6 had hypertension, 11,14,19,31 2 (6.1%) had high cholesterol, 11,31 2 had hypothyroidism, 15 2 had eczema, 23,31 one (3.0%) had syringomyelia, 13 one had IgE hypogammaglobulinemia, 22 one had previously been treated for tuberculosis, 24 one had rosacea in addition to PPOFG, 28 one had arthritis not otherwise specified, 31 one had rheumatoid arthritis, one had cardiomegaly, 31 one had chronic idiopathic panuveitis with an onset 8 years prior, 34 one had liver cirrhosis, and one had sleep apnea.…”

Section: Resultsmentioning

confidence: 99%

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Primary Periocular Orofacial Granulomatosis: Case Series and Systematic Review

Plemel

Weis

Punja

et al. 2023

Ophthalmic Plastic &Amp; Reconstructive Surgery

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Purpose: There is no known optimal treatment for primary periocular orofacial granulomatosis (PPOFG), a disorder that results in periocular edema. This case series and systematic review identifies management strategies and their reported improvement. Methods: Systematic review and case series. PubMed and MEDLINE databases were searched following the Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines to identify published cases of PPOFG. Cases were included when edema involved the periocular tissues and when a biopsy was interpreted to be PPOFG. Cases were excluded when edema did not involve the periocular tissues or when the edema was secondary to another process. The electronic medical records of the pathology department were studied to identify cases that were in keeping with PPOFG. The clinical charts were examined to confirm the diagnosis and provide a local case series. Results: There are 38 published cases of PPOFG. An additional 9 cases were identified locally. These cases were combined and analyzed. Most PPOFG has eyelid swelling in isolation, without other facial swelling (36/47; 76.6%). It is most commonly a bilateral disease (30/47; 63.8%). Fissured tongue and facial nerve palsy occur, just as they do in other cases of orofacial granulomatosis. Treatment with surgical debulking or intralesional steroids resulted in high rates of symptomatic improvement of eyelid swelling, but recurrences were common. Conclusions: In light of no curative or highly successful treatment currently available, intralesional steroids and/or surgical debulking are therapies in the treatment of eyelid swelling associated with PPOFG that demonstrate reasonable short- and medium-term results. There is no established therapy that can offer disease remission or long-term symptom improvement.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Primary Periocular Orofacial Granulomatosis: Case Series and Systematic Review

Plemel

Weis

Punja

et al. 2023

Ophthalmic Plastic &Amp; Reconstructive Surgery

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Diagnostic performance of Sjögren’s Syndrome Screening Questionnaire (SSSQ)

et al. 2022

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Oral and Maxillo-Facial Manifestations of Systemic Diseases: An Overview

2021

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Many systemic (infective, genetic, autoimmune, neoplastic) diseases may involve the oral cavity and, more generally, the soft and hard tissues of the head and neck as primary or secondary localization. Primary onset in the oral cavity of both pediatric and adult diseases usually represents a true challenge for clinicians; their precocious detection is often difficult and requires a wide knowledge but surely results in the early diagnosis and therapy onset with an overall better prognosis and clinical outcomes. In the current paper, as for the topic of the current Special Issue, the authors present an overview on the most frequent clinical manifestations at the oral and maxillo-facial district of systemic disease.

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Orofacial Edema and Facial Paralysis

Cited by 4 publications

References 2 publications

Primary Periocular Orofacial Granulomatosis: Case Series and Systematic Review

Primary Periocular Orofacial Granulomatosis: Case Series and Systematic Review

Diagnostic performance of Sjögren’s Syndrome Screening Questionnaire (SSSQ)

Oral and Maxillo-Facial Manifestations of Systemic Diseases: An Overview

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