Development of an interactive e-module of integrated science with the Connected type on energy topic for Junior High School (SMP) aims to develop an interactive e-module of integrated science that includes biology, physics, and chemistry concepts an interrelate unity in energy topics. That expected to strengthen the student concept knowledge. The Research and Development (R & D) design with the Plomp model was employed. Collection data procedures used validation sheets and user responses questionnaires by the validator team, teachers, and students. Assessments involved material substance, learning design, display (visual communication), and software utilization. Data analysis results showed the validation percentage from the material and media experts are 94.99% and 96.96%, with very valid criteria. Through the teacher's responses, obtain 95.00% (very good practicality criteria). The 92.45% on the one and one test and 92.71% on the small group test, both on very interesting criteria from students. Its means, the interactive e-module has been valid and suitable for use in the learning process.