Orbital Invasion by Esthesioneuroblastoma

Abstract

Orbital invasion by esthesioneuroblastoma is not uncommon. It is important to be aware of this malignancy because a significant proportion of patients will present with ophthalmic signs and symptoms.

An isolated orbital mass with proptosis and diplopia: an uncommon metastasis from intracranial olfactory neuroblastoma in a Chinese patient

“…The location and morphology of the orbital tumor in our case was unique compared to the ones mentioned in previous studies. [4][5][6][7][8][9] Cytopathological and immunohistochemical features of the orbital neoplasm were found to be consistent with the features of primary intracranial tumors. So we speculate that the orbital neoplasm in our case is a metastasis rather than an infiltration from the primary lesion.…”

“…2,3 Cases of ONB with ophthalmologic presentations, including epiphora, decreased visual acuity, and proptosis, have been reported previously. [4][5][6][7][8][9] In these orbital malignant cases, the infiltrating neoplasm invaded orbits directly through bone destruction or the cranio-orbital communication anatomical structure. Herein we report a novel case of orbital metastasis from intracranial ONB in a Chinese patient demonstrating a possible uncommon approach of ONB migration to orbits.…”

“…[4][5][6][7][8][9] In orbital tumor cases, the infiltrating neoplasm invades the orbit by bone destruction, which can be clearly observed by imaging examinations. 12 However, in our patient's CT images, the orbital neoplasm was an isolated homogenous mass occupying the upper inner position of the right orbit, which does not support the possibility of direct invasion (Figure 1).…”