The Orbit: Biopsy, Excision Biopsy, and Exenteration Specimens

Roberts, Fiona; Thum, Chee Koon

doi:10.1007/978-1-4471-2476-4_12

Cited by 1 publication

(1 citation statement)

References 175 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In addition, a complete eye examination should be carried out [ 20 ], including slit-lamp biomicroscope magnification, ophthalmoscopy, tonometry, ocular ultrasound, and gonioscopy [ 12 , 20 , 55 ]. When required, magnetic resonance imaging and computed tomography can be performed, providing a detailed and complete assessment of the orbital region [ 20 , 38 , 56 ]. The complementary diagnostic exams are essential to evaluate the involved structures, identify the neoplasia’s margins and extent, and define the most appropriate treatment strategy [ 25 ].…”

Section: Introductionmentioning

confidence: 99%

Current Therapeutics and Future Perspectives to Ocular Melanocytic Neoplasms in Dogs and Cats

Guimarães

Cardoso

Tralhão³

et al. 2021

Bioengineering

View full text Add to dashboard Cite

Neoplasms of melanocytic origin are diseases relevant to dogs and cats’ ophthalmic oncology due to their incidence, potential visual loss, and consequent decrease in life quality and expectancy. Despite its non-specific clinical presentation, melanocytic neoplasms can be histologically distinguished in melanocytomas, which present benign characteristics, and malignant melanomas. The diagnosis often occurs in advanced cases, limiting the therapeutic options. Surgery, cryotherapy, radiotherapy, photodynamic therapy (PDT), and laser are currently available therapeutic strategies. As no clinical guidelines are available, the treatment choice is primarily based on the clinician’s preference, proficiency, and the owner’s financial constraints. While surgery is curative in benign lesions, ocular melanomas present a variable response to treatments, besides the potential of tumour recurrences or metastatic disease. This review presents the currently available therapies for ocular melanocytic neoplasms in dogs and cats, describing the therapeutic, indications, and limitations. Additionally, new therapeutics being developed are presented and discussed, as they can improve the current treatment options.

show abstract