Oral premalignant lesions: a clinicopathological study

Jagtap, Sunil Vitthalrao; Warhate, Pranita; Saini, Neetu; Jagtap, Swati Sunil; Chougule, Pandurang G.

doi:10.18203/2349-2902.isj20174520

Cited by 13 publications

(13 citation statements)

References 16 publications

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“…Our results were less compared to the corresponding values of 77.1% reported by Gupta et al 5 in Lucknow but distinctly higher than several other studies in India such as Saraswathi et al 6 We observed that highest number of PMD cases were in 50-60 yrs of age group (69.2%). This was comparable to the results from Kadashhetti et al 1 , Saraswathi et al 6 and Jagtap et al 10 . Several studies have reported equal prevalence of PMD among the middle aged and elderly subjects 8 whereas few others have reported highest prevalence in 21-30 years of age group 11 which was not in accordance with our study.…”

Section: Discussionsupporting

confidence: 91%

Prevalence of oral potentially malignant disorders associated with habits in Puducherry

Paulose¹,

Rangdhol²,

Kavya³

et al. 2020

Braz. J. Oral Sci.

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Tobacco and betel quid are the most common cause of oral cancer in India. Very often oral cancers are preceded by a visible oral precursor lesion called as potentially malignant disorder (PMD). Aim: The aim of this study was to assess the prevalence of oral PMDs associated with habits in urban and rural areas of Puducherry Union territory, India. Methods: A cross-sectional descriptive study in urban and rural areas of Puducherry was conducted. The study group comprised of 450 patients with positive history of oral habits. A standard structured questionnaire was designed to record information about demographic details, socioeconomic status, type, duration and frequency of habits followed by clinical oral examination by single trained and calibrated examiner to detect the presence of PMD. Statistical analysis used: EpiData software (version 3.1). Descriptive statistics were presented for all variables. Pearson’s Chi-Square test and adjusted odds ratio (ORs) with 95% confidence interval (CI) were calculated to estimate the suspected risk factors for PMD by using multivariate logistic regression analysis. P-value of ≤ 0.05 was considered to be statistically significant. Results: Prevalence of habit associated oral PMD was 64.2%. Females were more prone to develop PMDs (68.3%) as compared to males (62.8%). PMD was more common in the age group of 51-60 years (69.2%). Smoking with alcohol consumption was the most common oral habit. Habits, socio-economic status and diet were significantly associated with development of oral PMDs in our study population. Multivariate logistic regression analysis showed that chronic betel quid chewing and smoking were significant risk factors for PMD. Increased frequency of vegetable consumption reduced the risk of PMD. Conclusions: Oral PMD were observed in more than half of the subjects with oral habits in Puducherry. Clearly, there is an increased risk of PMD with increased duration of tobacco and betel quid use in this region. Patients and public need to be educated regarding PMD and encouraged to quit habits so as to prevent high risk population from developing cancer.

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Section: Discussionsupporting

confidence: 91%

Prevalence of oral potentially malignant disorders associated with habits in Puducherry

Paulose¹,

Rangdhol²,

Kavya³

et al. 2020

Braz. J. Oral Sci.

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“…According to Anna Starzyńska et al [15], the most common site involved was buccal mucosa (52.2%). Whereas buccal mucosa involvement was 55.26% in a study by Sunil Vitthalrao Jagtap et al [13].…”

Section: Resultsmentioning

confidence: 92%

“…Cessation of smoking habits may result in regression or even disappearance of the leukoplakia and diminish the risk of cancer development either at the site of the leukoplakia or elsewhere in the mouth or the upper aerodigestive tract. Sunil Vitthal Rao et al [13] mentioned that 68.41% of cases were leukoplakia followed by oral lichen planus (13.16%) oral submucous fibrosis (7.9%). According to Buoquot et al [14] leukoplakia is the most common cause.…”

Section: Resultsmentioning

confidence: 99%

“…Age-wise, the majority (33.33%) of the study participants were aged 51-60 years followed by the 61-70 (, 23.53%) group. According to Sunil Vitthalrao Jagtap et al [13], 50-59 years is the common age group. Whereas common age was reported to be 50 -70 years according to Anna Starzyńska et al [15], According to previous studies, cases with multiple oral premalignant lesions were more likely to be in the 45-54 year age group.…”

Section: Resultsmentioning

confidence: 99%

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Relationship between habits and precancerous lesions of the oral cavity – a clinicopathological study

Yadlapalli¹,

Santosh²,

Veeranjaneyulu³

et al. 2021

Trop J Ophthalmol Otolaryngol

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Introduction: Oral cancers account for 3% of total malignancies. A research was conducted to findthe incidence, age, and sex distribution, clinical presentation, and the relationship between habitsand various premalignant lesions of the oral cavity. Methods: It was a hospital-based observationaland cross-sectional study, conducted in GSL Medical College, Rajamahendravaram from October2015 to April 2017. Individuals aged > 18 years, with leukoplakia, erythroplakia, blanched mucosawith or without fibrous bands and /or trismus suggestive of oral submucous fibrosis, bilateral whitishlesions with a reticular pattern suggestive of lichen planus, and ulcer against sharp tooth denturesuggestive of traumatic dental ulcers were taken. Individuals with frank oral malignancy, those withterminal diseases, those who did not submit informed consent were not considered. Results: Themajority of patients (33.33%) were aged between 51 – 60 years, belong (62.75%) to lowersocioeconomic status. Leukoplakia (64.7%) was a common clinical presentation. Most (49.02%) ofthe study patients presented with a burning sensation. When addictions were considered, 86.27% ofpatients were smokers, 23.53% were addicted to alcohol. Conclusion: Leukoplakia was thecommonest (64.71%) premalignant lesion, 51 – 60 years was the common age group. Premalignantlesions were most commonly seen among males, most of the study participants belong to low andmiddle socio-economic groups with a rural background. Diabetes mellitus was the most commoncomorbidity associated with premalignant lesions.

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“…9,10 Jagtap et al in their study found leukoplakia to comprise 68.41% of their study population. 11 As far as OSMF is concerned, a number of studies have reported it to be dominant premalignant type reporting in 30.4% to 88.1% of premalignant lesions. [12][13][14] In present study, majority of cases had involvement of multiple sites.…”

Section: Discussionmentioning

confidence: 99%

Spectrum of premalignant oral lesions in rural North Indian population at a tertiary care hospital

Faiz

Agarwal

Bhargava

et al. 2018

Int J Otorhinolaryngol Head Neck Surg

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Background: The objective of the study was to study the spectrum of premalignant oral lesions in rural North Indian population at a tertiary care hospital.Methods: A total of 340 patients with oral lesions for more than 2 weeks were enrolled in the study. Patients with proven malignancy, white patch in the oral cavity which can be scrapped off, e.g. oral candidiasis and urban patients were excluded. Biopsy specimen was obtained from all the patients and evaluated histopathologically. Site, nature and type of oral lesion were determined. Demographic data and exposure to different risk factors was also noted. Findings were correlated using Chi-square test. Results: Premalignant lesions were seen in 191 (56.18%) cases. They included leukoplakia (n=87; 45.5%), OSMF (n=62; 32.5%), Erythroplakia (n=18; 9.4%), lichen planus (n=15; 7.9%), melanoplakia/ melanosis (n=8; 4.2%) and DLE (n=1; 0.5%) respectively. Most common sites affected by premalignant lesions were buccal mucosa (n=173; 90.6%), retromolar area (n=42; 22%). Majority of patients with premalignant lesions were aged 26-50 years (78.5%), males (62.8%), farmers/labourers (56%) and illiterate/educated upto primary level (57.1%). Almost all the patients had two or more adverse oral habits with areca nut chewing being most common (69.6%) followed by tobacco chewing (66%) and smoking (60.2%) respectively. Majority had these addictions for >5 years (66%).Conclusions: Leukoplakia and OSMF dominated the premalignant lesions in rural patients having low education and high prevalence of adverse oral habits for prolonged duration.

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Oral premalignant lesions: a clinicopathological study

Cited by 13 publications

References 16 publications

Prevalence of oral potentially malignant disorders associated with habits in Puducherry

Prevalence of oral potentially malignant disorders associated with habits in Puducherry

Relationship between habits and precancerous lesions of the oral cavity – a clinicopathological study

Spectrum of premalignant oral lesions in rural North Indian population at a tertiary care hospital

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