Oral histoplasmosis in Brazil

Ferreira, O Gomes; Cardoso, Sérgio Vitorino; Borges, Aércio Sebastião; Ferreira, Marcelo Simão; Loyola, Adriano Mota

doi:10.1067/moe.2002.122588

Cited by 44 publications

(35 citation statements)

References 46 publications

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“…Oral lesions can manifest as papular, ulcerative, nodular, vegetative, furunculoid, granulomatous, or plaque-like lesions, with the most common presentation being a shallow or deep infiltrated ulceration with a pseudomembrane. [1–5910] Gingival manifestations include ulcerative and painful granulomatous lesions. [8] Sore throat, hoarseness of voice, and dysphagia can also manifest.…”

Section: Discussionmentioning

confidence: 99%

Oral histoplasmosis

Patil

Mahima

Rani

2009

J Indian Soc Periodontol

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Histoplasmosis is a systemic fungal disease that takes various clinical forms, among which oral lesions are rare. The disseminated form of the disease that usually occurs in association with Human Immunodeficiency Virus (HIV) is one of the AIDS-defining diseases. Isolated oral histoplasmosis, without systemic involvement, with underlying immunosuppression due to AIDS is very rare. We report one such case of isolated oral histoplasmosis in a HIV-infected patient.

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Section: Discussionmentioning

confidence: 99%

Oral histoplasmosis

Patil

Mahima

Rani

2009

J Indian Soc Periodontol

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“…Histoplasmosis is endemic in the central eastern united states, especially the Ohio and Mississippi River Valleys, in Central and South America, and Africa, but is less frequently reported in Asia and Europe. [23] Reported cases of histoplasmosis have been low in India with less than 50 cases being reported. [24]…”

Section: Introductionmentioning

confidence: 99%

“…[5] In human immunodeficiency virus (HIV) positive patients, 95% of histoplasmosis appears as disseminated infection. [3] Occurrence of disseminated form of histoplasmosis is rare in HIV seronegative patients. The disease is rarely fatal and usually manifests as self-limited pneumonia.…”

Section: Introductionmentioning

confidence: 99%

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Disseminated histoplasmosis with oral and cutaneous manifestations

Vidyanath

Shameena

Sudha

et al. 2013

J Oral Maxillofac Pathol

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Histoplasmosis is a systemic mycotic infection caused by the dimorphic fungus, Histoplasma capsulatum. Systemic histoplasmosis has emerged as an important opportunistic infection in human immunodeficiency virus (HIV) patients and those in endemic areas. Reported cases of histoplasmosis have been low in India with less than 50 cases being reported. We are reporting a case of disseminated histoplasmosis with oral and cutaneous involvement in an HIV seronegative patient.

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“…Patients with laryngeal histoplasmosis usually exhibit low-grade fever, weight loss, sore throat, hoarseness, cough and dysphagia, which can cause diagnostic difficulty as these symptoms are also seen in malignancy 4. On laryngoscopy, mucosa is pearly white, oedematous, inflamed or painful ulcerative, again mimicking the typical findings of malignancy 12. On histopathology of histoplasmosis, many differentials are to be kept in mind, such as cryptococcosis and blastomycoses (fungal infections having similar microscopic features), tuberculosis (confluent caseating granulomas) and squamous cell carcinoma (pseudo-epitheliomatous hyperplasia with infiltrating atypical malignant squamous cells) 2…”

Section: Discussionmentioning

confidence: 99%

Laryngeal histoplasmosis

Ansari

Saeed²,

Khan

et al. 2016

BMJ Case Reports

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Histoplasmosis is a fungal infection, having interesting synonyms such as Cave disease, Darling's disease, Ohio Valley disease, reticuloendotheliosis, Spelunker's lung and Caver's disease. The aetiological agent is a dimorphic fungus, Histoplasma capsulatum, causing chronic granulomatous disease. The route of transmission is by inhalation of dust particles from soil contaminated by excrement of birds or bats, harbouring the small spores or microconidia, which is considered the infectious form of fungus. The spectrum of illness ranges from subclinical infection of the lung to progressive disseminated disease. The major bulk of histoplasmosis infections are asymptomatic or present with mild influenza like illness and involve immunocompetent individuals. However, the immunocompromised or immunodeficient cases have disseminated/haematogenous infections with multiple organs involved and are usually fatal unless treated immediately. Laryngeal involvement is associated with the disseminated form of the disease. Histoplasmosis of larynx is a rare entity and poses diagnostic difficulty to otolaryngologists because clinically it may be mistaken for malignancy. We report an unusual case of laryngeal histoplasmosis in a man aged 60 years who presented with provisional diagnosis of tuberculosis/malignancy.

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Oral histoplasmosis in Brazil

Cited by 44 publications

References 46 publications

Oral histoplasmosis

Oral histoplasmosis

Disseminated histoplasmosis with oral and cutaneous manifestations

Laryngeal histoplasmosis

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