Oral Candidal Infection and Denture Stomatitis: A Comprehensive Review

Is Topical Antifungal the Appropriate First Choice for Denture Stomatitis?

“…Systemically, Azole antifungals (ketoconazole and fluconazole) are the drugs most used [28][29][30][31][32][33][34]. Systemic therapy has been prescribed for DS in cases not responding to topical agents or in cases with presence of systemic factors, such as immunosuppression or diabetes [35][36][37]. Generally, the dentists are concerned about prescribing systemic antifungals because of the risk of side effects.36 Conversely, in vivo studies reported the efficacy of systemic antifungals with minimal or no side effects to treat patients with DS through [1,21,25,38].…”

Evaluation of Effect of Oral Microorganism on Surface Topography of Arylic Resin Denture Base Materialby Three Dimensional Profilometry Using Laser Triangulation Sensor- In Vitro Study

“…14,16,17,18 these yeasts are present in the saliva of a majority of denture wearers and display an affinity for adherence to acrylic resin. They not only hamper the smoothness of acrylic surface but also responsible for denture stomatitis, Cahn 1936, Callar 1945.…”

Effect of affordable disinfectant solutions on Candida albicans adhered to acrylic resin for dental prosthesis

“…The safety of the use of solutions as chlorhexidine, sodium hypochlorite, vinegar and hydrogen peroxide is reported in the literature [16][17][18][19][20][21][22][23][24] . They presented biocompatibility and low cytotoxicity when used in low concentrations being safe for denture chemical disinfection.…”