DS children have higher salivary sIgA concentrations than non-DS children. However, this finding did not correlate with caries experience in the study population.

There is no scientific evidence to support the hypothesis that people with Down syndrome have a lower experience of caries than non-syndromic individuals.

The present results suggest that despite the salivary composition being similar between groups, the dental biofilm of children with DS has higher cariogenic potential than that of children without this condition.

Aims To evaluate the genotypic diversity and acidogenicity of Streptococcus mutans (S. mutans) and the potential association of these factors with dental caries experience in children with DS compared to non‐DS children (controls). Methods and results Seventeen children (age 6‐12 years) with high salivary S. mutans counts (> 2.5 × 105 CFU/mL) were selected and divided into two groups: DS and non‐DS. Five children in each group were caries‐free, while the remainder had elevated caries experience. S. mutans isolates were obtained from each participant. The genotypic profile of the isolates was analyzed with the AP‐PCR methodology. The acidogenicity of a representative strain from each genotype of S. mutans was also evaluated. DS children had 16 different S. mutans genotypes, while the control group had 21. Twelve genotypes were present in both groups and one of them was associated with caries‐free status (P < .05). Although the acidogenicity of the genotypes found in DS children was significantly lower (P < .05) compared to controls, this fact was not associated with caries experience in both groups. Conclusions DS children have a lower S. mutans genotypic diversity and genotypes with lower acidogenicity than those of non‐DS children. However these findings were not associated with their caries experience.

ObjectiveTo evaluate the effect of different low-cost disinfectant solutions on Candida albicans (C. albicans) adhered to acrylic resin used in dental prosthesis. Methods Sixty acrylic resin specimens were divided into four experimental groups according to the disinfecting agent tested (2% chlorhexidine, 1% sodium hypochlorite, vinegar and 10v hydrogen peroxide) and two control groups. Fifty specimens were incubated with C. albicans and after immersed in the disinfecting solutions or saline (negative control). Specimens without contamination constituted the positive control group. After disinfection procedures, all specimens were immersed in a culture medium and incubated for 24 hours at 37°C. Culture media turbidity was evaluated. Results The disinfectants 2% chlorhexidine and 1% sodium hypochlorite performed a maximal reduction of C. albicans. Vinegar showed intermediate antifungal effect and 10v hydrogen peroxide showed a lower effect.Conclusions Among the disinfecting solutions tested in the present study, 2% chlorhexidine and 1% sodium hypochlorite are the most effective in the reduction of C. albicans adhered to acrylic resin. However, vinegar may represent a viable and low-cost alternative to prosthesis disinfection.