Oral aspects in celiac disease children: clinical and dental enamel chemical evaluation

Carvalho, Fabrício Kitazono de; Queiroz, Alexandra Mussolino de; Sawamura, Regina; Bachmann, Luciano; Silva, Léa Assed Bezerra da; Filho, Paulo Nelson

doi:10.1016/j.oooo.2015.02.483

Cited by 49 publications

(121 citation statements)

References 22 publications

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“…DEDs are related to the ameloblasts malfunction, because these cells are sensitive to many environmental and systemic alterations . In fact, DEDs have been also associated with some serious and/or chronic illnesses including CD …”

Section: Discussionmentioning

confidence: 99%

“…The CD clinical signs and symptoms have a wide spectrum with different degrees, which can range from “classic” (e.g., chronic diarrhea, weight loss, pain and abdominal distension caused by villous atrophy of the small intestine) to “atypical” that a lack of intestinal symptoms occurs (e.g., fatigue, iron deficiency anemia, dermatitis herpetiformis, short stature, and oral manifestations) …”

Section: Introductionmentioning

confidence: 99%

“…DEDs are a common alteration in CD individuals and its prevalence ranges between 38% to over 80% . DEDs tend to present a symmetrical phenotype in all four hemiarches, in which the most commonly affected teeth are incisors and molars …”

Section: Introductionmentioning

confidence: 99%

“…Although a strong association between CD and DEDs has been widely reported, the nature of this relationship is still largely unclear. There are some theories whether CD and DEDs share a common genetic background or if DEDs are caused by the CD nutritional deficiencies.…”

Section: Introductionmentioning

confidence: 99%

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Assessing the proposed association between DED and gluten‐free diet introduction in celiac children

Queiroz

Arid

Carvalho

et al. 2017

Special Care in Dentistry

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A strong association between celiac disease (CD) and dental enamel defects (DEDs) have been extensively reported, however, the nature of this relationship is still unclear. The aim of this study was to evaluate DEDs phenotype in CD individuals according to the time they were introduced to a gluten-free diet (GFD). Forty-five CD individuals were examined by a pediatric dentist. DEDs were classified according to the type of affected teeth. CD individuals were classified into two groups (with or without DEDs) and the differences between these groups were tested using chi-square or Fisher´s exact tests and t-test to compare differences between means. The Pearson coefficient test was used to evaluate the degree of the correlation between the age of GFD introduction and number of affected teeth. Individuals with MIH were introduced earlier to the GFD (p = 0.038). An association was also observed for molar DED (p = 0.013). In conclusion, our study suggested an association between a specific type of DED and the time that CD individuals were introduced to a GFD.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Assessing the proposed association between DED and gluten‐free diet introduction in celiac children

Queiroz

Arid

Carvalho

et al. 2017

Special Care in Dentistry

Self Cite

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“…They found the Calcium/Phosphorous ratio to be significantly lower in the teeth of the children affected by CD 20 . The decrease in Calcium/Phosphorous ratio could be explained by the incorporation of carbonate in the tissue structure, which would increase its solubility 21 .…”

Section: Clinical Presentationmentioning

confidence: 98%

Coeliac disease in children – an update for general dental practitioners

et al. 2016

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Coeliac disease (CD) is an immune-mediated systemic disorder caused by ingestion of gluten found in wheat, rye and barley. It affects around 1% of children but 90% of cases are considered to remain undiagnosed. CD classically presents with gastrointestinal manifestations including diarrhoea, bloating, weight loss and abdominal pain, but extra-intestinal features (including oral and dental manifestations) are increasingly being reported. Dental and oral manifestations such as dental enamel defects, delayed eruption of teeth, recurrent aphthous ulcers are well recognized manifestations of CD. In patients with yet undiagnosed CD, these can sometimes be the only presenting features. Dentists have regular contact with well children, and therefore the visit to the dentist is an opportunity to suspect CD. When CD is suspected, Dental practitioners can liaise with the General Medical Practitioner to organise screening for coeliac disease. Positive serology will prompt onward referral to a paediatric gastroenterologist to confirm the diagnosis. The recent European Paediatric Gastroenterology Hepatology and Nutrition (ESPGHAN) guidelines have streamlined the diagnostic pathway for faster diagnosis of CD. Management involves strict adherence to a gluten free diet, which should lead to resolution of symptoms, recovery of intestinal mucosa and prevention of long-term complications associated with it. This article aims to describe CD, inform of recent changes to the diagnostic pathway and highlight the dental manifestations of the condition to equip Dental practitioners to aid early diagnosis and initiation of treatment for children with CD.

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Oral Ulcerative Lesions

Lodi

Varoni

Robledo‐Sierra

et al. 2017

Contemporary Oral Medicine

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Oral aspects in celiac disease children: clinical and dental enamel chemical evaluation

Abstract: The children with CD presented with more RAS, DEDs, reduction of salivary flow, and chemical alterations in the enamel.

Cited by 49 publications

References 22 publications

Assessing the proposed association between DED and gluten‐free diet introduction in celiac children

Assessing the proposed association between DED and gluten‐free diet introduction in celiac children

Coeliac disease in children – an update for general dental practitioners

Oral Ulcerative Lesions

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