Oral antifungal therapy: Emerging culprits of cutaneous adverse drug reactions

Chaudhary, Raju G; Rathod, Santoshdev P; Jagati, Ashish; Zankat, Dhara; Brar, Arwinder Kaur; Mahadevia, Bansri

doi:10.4103/idoj.idoj_353_18

Cited by 9 publications

(2 citation statements)

References 12 publications

(14 reference statements)

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“…vomiting, and diarrhea. 5 Other adverse effects include photosensitivity, fixed drug eruption, and urticaria. Photosensitivity limited to ears may be one reason in our case, which is not reported.…”

Section: Case Reportmentioning

confidence: 99%

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Griseofulvin‐Induced Red and Hot Ears

Mannu,

Kumar Verma,

Vasudevan

et al. 2023

The Journal of Clinical Pharma

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Dear Editor,Griseofulvin is a natural product, first isolated in 1939 from Penicillium griseofulvum and was first commercially introduced in 1959. It is a polyketide that is derived from acetyl and malonyl coenzyme A precursor molecules to form dehydrogriseofulvin. 1 It inhibits microtubule assembly, affects the formation of the mitotic spindle, and finally inhibits mitosis in dermatophytes. 2 Griseofulvin is mainly used for dermatophytes; however, other uses include anti-inflammatory, cardiovascular, antitumor, and antiviral activity. 3 It has mainly gastrointestinal side effects, but other adverse effects can also be noticed, such as photosensitivity, urticaria, and petechia. 4

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Section: Case Reportmentioning

confidence: 99%

“…Griseofulvin is a commonly used oral antifungal and is available in 2 forms, micro‐size and ultra‐micro‐size, with the absorption of the latter being better. Common adverse effects of griseofulvin include nausea, vomiting, and diarrhea 5 . Other adverse effects include photosensitivity, fixed drug eruption, and urticaria.…”

Section: Case Reportmentioning

confidence: 99%