Optimizing the ultrasound-assisted deep eutectic solvent extraction of flavonoids in common buckwheat sprouts

Mansur, Ahmad Rois; Song, Nho‐Eul; Jang, Hae Won; Lim, Tae‐Gyu; Yoo, Miyoung; Nam, Tae Gyu

doi:10.1016/j.foodchem.2019.05.003

Cited by 127 publications

(71 citation statements)

References 30 publications

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“…Different types of DESs (HBA: choline chloride and HBD: glycerol, 1,3-butanediol, 1,4-butanediol, glycol and glucose) have different physicochemical properties, such as solubility, viscosity, density and conductivity, which have an important effect on the anthocyanin yield and the extraction efficiency [ 28 ]. Consequently, choline chloride as the HBA and five types of HBDs (glucose, 1,3-butanediol, 1,4-butanediol, glycol and glycerol) were chosen to prepare DESs in this study.…”

Section: Resultsmentioning

confidence: 99%

Optimization Ultrasound-Assisted Deep Eutectic Solvent Extraction of Anthocyanins from Raspberry Using Response Surface Methodology Coupled with Genetic Algorithm

Xue

Tan

et al. 2020

Foods

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Raspberries have been reported to contain abundant anthocyanins and other active compounds. To extract anthocyanins from raspberries more efficiently, a novel procedure of ultrasound-assisted deep eutectic solvent extraction (UADESE) was proposed in this paper. The extraction process was optimized by response surface methodology coupled with a genetic algorithm. The optimum extraction parameters to achieve the highest yield of anthocyanins 1.378 ± 0.009 mg/g from raspberry powder via UADESE were obtained at a water content of 29%, ultrasonic power of 210 W, extraction temperature of 51 °C and extraction time of 32 min. The AB-8 macroporous resin combined with the high-speed counter current chromatography (HSCCC) method were further used to isolate and purify the anthocyanins extracts obtained under optimum extraction conditions, and the structure of purified anthocyanins components were identified by UV-Visible spectrophotometer (UV-Vis), high-performance liquid chromatography (HPLC), high-performance liquid chromatography-electrospray ionization-mass spectrometry (HPLC-ESI-MS/MS), 1H nuclear magnetic resonance (NMR) and 13C-NMR spectra. The two anthocyanins (cyanidin-3-glucoside with a purity of 92.25% and cyanidin-3-rutinoside with a purity of 93.07%) identified were consistent with those present in raspberries. These findings provided an effective and feasible method for extraction, isolation and purification of anthocyanins from natural plant resources.

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Section: Resultsmentioning

confidence: 99%

Optimization Ultrasound-Assisted Deep Eutectic Solvent Extraction of Anthocyanins from Raspberry Using Response Surface Methodology Coupled with Genetic Algorithm

Xue

Tan

et al. 2020

Foods

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“…Furthermore, the choice of the appropriate analytical method (especially extraction protocol) depends largely on the matrix itself. For example, bioactive compounds are nowadays extracted from a wide variety of plant matrices, including medicinal plants [46], cereals [47,48], fruits and vegetables [49], edible flowers [50], nuts [51], etc. Of particular importance is certainly the extraction of bioactive compounds from the nus-products of various industries, especially the food industry [52][53][54][55][56].…”

Section: Analytical Procedures For Determination Of Bioactive Compounmentioning

confidence: 99%

“…On the other hand, the combination of DES and UAE for the extraction of different flavonoid subclasses is most optimal when polyalcohol-based DES are used [47,48,[108][109][110][111]. For example, Mensur et al have optimized UAE-DES extraction of flavonoids in common buckwheat sprouts [47]. Nine different DES based on choline chloride and various HBD (acetamide, triethylene glycol, 1,2-propanediol, 1,4-butanediol, urea, ethylene glycpol, glycerol, oxalic acid and malonic acid) were evaluated.…”

Section: Ultrasound-assisted Des/nades Extractions Of Bioactive Compomentioning

confidence: 99%

Innovative Extraction Techniques Using Deep Eutectic Solvents and Analytical Methods for the Isolation and Characterization of Natural Bioactive Compounds from Plant Material

Ivanović

Razboršek

Kolar

2020

Plants

120

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The growing interest of the food, pharmaceutical and cosmetics industries in naturally occurring bioactive compounds or secondary plant metabolites also leads to a growing demand for the development of new and more effective analysis and isolation techniques. The extraction of bioactive compounds from plant material has always been a challenge, accompanied by increasingly strict control requirements for the final products and a growing interest in environmental protection. However, great efforts have been made in this direction and today a considerable number of innovative extraction techniques have been developed using green, environmentally friendly solvents. These solvents include the deep eutectic solvents (DES) and their natural equivalents, the natural deep eutectic solvents (NADES). Due to their adjustable physical-chemical properties and their green character, it is expected that DES/NADES could be the most widely used solvents in the future, not only in extraction processes but also in other research areas such as catalysis, electrochemistry or organic synthesis. Consequently, this review provided an up-to-date systematic overview of the use of DES/NADES in combination with innovative extraction techniques for the isolation of bioactive compounds from various plant materials. The topicality of the field was confirmed by a detailed search on the platform WoS (Web of Science), which resulted in more than 100 original research papers on DES/NADES for bioactive compounds in the last three years. Besides the isolation of bioactive compounds from plants, different analytical methods are presented and discussed.

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“…DESs/NADESs have important advantages over conventionally used organic solvents, such as no or low toxicity, biodegradability, low cost and easy preparation [24]. While the efficiency of classical extraction processes can be significantly improved by applying UAE [35,36], a combination of UAE and NADESs can be also effective [33,[37][38][39].…”

Section: Introductionmentioning

confidence: 99%

Choline Chloride Based Natural Deep Eutectic Solvents as Extraction Media for Extracting Phenolic Compounds from Chokeberry (Aronia melanocarpa)

et al. 2020

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For the isolation of selected phenolic compounds from dried chokeberries, natural deep eutectic solvents (NADESs) were investigated as a green alternative to conventionally used extraction solvents. Four types of NADESs were synthesised, with choline chloride as the hydrogen bond acceptor in combination with different hydrogen bond donors (sugars, organic acid and urea). Ultrasound-assisted extraction was used to improve the extractability of the phenolic compounds and the results were compared to those obtained with 80% methanol as the extraction media. The highest values of total phenols and total flavonoids were found in the extract obtained with choline chloride–fructose NADES (36.15 ± 3.39 mg gallic acid g−1 dry weight (DW) and 4.71 ± 0.33 mg rutin g−1 DW, respectively). The extraction recoveries for the individual phenolic compounds depended strongly on the phenolic compound’s structure, with relative mean values between 70% and 97%.

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Optimizing the ultrasound-assisted deep eutectic solvent extraction of flavonoids in common buckwheat sprouts

Cited by 127 publications

References 30 publications

Optimization Ultrasound-Assisted Deep Eutectic Solvent Extraction of Anthocyanins from Raspberry Using Response Surface Methodology Coupled with Genetic Algorithm

Optimization Ultrasound-Assisted Deep Eutectic Solvent Extraction of Anthocyanins from Raspberry Using Response Surface Methodology Coupled with Genetic Algorithm

Innovative Extraction Techniques Using Deep Eutectic Solvents and Analytical Methods for the Isolation and Characterization of Natural Bioactive Compounds from Plant Material

Choline Chloride Based Natural Deep Eutectic Solvents as Extraction Media for Extracting Phenolic Compounds from Chokeberry (Aronia melanocarpa)

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