Optimization of extraction parameters of bioactive components from defatted marigold (Tagetes erecta L.) residue using response surface methodology

Gong, Ying; Hou, Zhanqun; Gao, Yanxiang; Xue, Yansong; Liu, Xin; Liu, Guangmin

doi:10.1016/j.fbp.2010.12.004

Cited by 122 publications

(62 citation statements)

References 30 publications

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“…The ABTS radical scavenging activity assay was performed according to the method described by Gong et al (2012a). The ABTS •+ was prepared by adding 7 mM ABTS stock solution into 2.45 mM potassium persulfate and keep the mixture for 16 h at room temperature in the dark.…”

Section: Abts Radical-scavenging Assaymentioning

confidence: 99%

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In vitro antioxidant, anti-diabetic and antilipemic potentials of quercetagetin extracted from marigold (Tagetes erecta L.) inflorescence residues

Wang

Chen

et al. 2016

J Food Sci Technol

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Quercetagetin, the major flavonoid in marigold (Tagetes erecta L.) inflorescence residues was extracted and purified. The content of quercetagetin after the purification was 89.91 ± 0.26 %. The in vitro antioxidant activity of quercetagetin and its potential in controlling diabetes mellitus and obesity were investigated and compared to quercetin and rutin. The 50 % inhibitory concentration (IC 50 ) values of quercetagetin on scavenging 1, 1-diphenyl-2-picrylhydrazyl (DPPH), 2,2-azinobis-(3-ethylbenzothiazolin-6-sulfonic acid) (ABTS) and hydroxyl radicals were 27.12 ± 1.31 μmol/L, 12.16 ± 0.56 μmol/L and 1833.97 ± 6.66 μmol/L, respectively. The IC 50 values of quercetagetin on α-glucosidase, α-amylase and pancreatic lipase were 180.11 ± 3.68 μmol/L, 137.71 ± 3.55 μmol/L and 2327.58 ± 12.37 μmol/L, respectively. These results indicated that quercetagetin exhibited strong in vitro antioxidant, anti-diabetic and antilipemic activities. Lineweaver-Burk plots analysis elucidated that quercetagetin inhibited α-glucosidase and α-amylase non-competitively, while its inhibition against pancreatic lipase was involved in a mixed-type pattern. Moreover, strong correlations were found between ABTS ·+ /DPPH · scavenging activities and lipase inhibitory activity (R 2 > 0.90), as well as ·OH scavenging activity and α-amylase inhibitory activity (R 2 = 0.8967).

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Section: Abts Radical-scavenging Assaymentioning

confidence: 99%

“…The DPPH radical scavenging activity assay was performed according to the method described by Gong et al (2012a) with minor modification. The sample or positive controls (quercetin and rutin) (2 mL) was mixed with 2 mL of freshly prepared DPPH (0.175 mM in methanol) and the mixture was vibrated for 20 s at room temperature.…”

Section: Antioxidant Capacity Assaysmentioning

confidence: 99%

In vitro antioxidant, anti-diabetic and antilipemic potentials of quercetagetin extracted from marigold (Tagetes erecta L.) inflorescence residues

Wang

Chen

et al. 2016

J Food Sci Technol

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“…The three independent variables considered were drying temperature (x1 , A), extraction temperature (x2 , B) and extraction time (x3 , C) while response variable was the yield of TPC. A central composite design (CCD) was selected for the optimization of process with 20 runs, including six replicates at central point [13]. In Table 1 (1) where Yn represent the response variables, a0 is a constant, ai, aii and aij are the linear, quadratic and interactive coefficients, respectively.…”

Section: Response Surface Methodologymentioning

confidence: 99%

Application of Response Surface Methodology in Extraction of Bioactive Component from Palm Leaves (Elaeis guineensis)

et al. 2013

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-The hydroxyl groups of the polyphenols are capable to act as reducing agent for reduction reaction. The effect of drying temperature, extraction temperature and extraction duration were evaluated using central composite design which consists of 20 experimental runs. Response surface methodology (RSM) was used to estimate the optimum parameters in extracting polyphenols from the palm leaves. The correspondence analysis of the results yielded a quadratic model which can be used to find optimum conditions of extraction process. The optimum extraction condition of drying temperature, extraction temperature and extraction duration are 70°C, at 70°C of 10 minutes, respectively. Total polyphenols were determined by application of the Folin-Ciocalteu micro method and the extract was found contain of 8 mg GAE/g dry palm leaves at optimum conditions.

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“…content was determined using a Sodium nitrite and Aluminium chloride colorimetric method described previously (Gong et al, 2012) and slightly modified. Briefly, 2 mL of sample was placed in The flavonoids yield of ultrasonic-assisted extraction was calculated using the following formula (1):…”

Section: Determination Of Total Flavonoids Content the Total Flavonoidsmentioning

confidence: 99%

Response Surface Optimization of Extraction and Antioxidant Activity of Total Flavonoids from Seed Shell of Juglans mandshurica

Bao

2014

FSTR

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Optimization of extraction parameters of bioactive components from defatted marigold (Tagetes erecta L.) residue using response surface methodology

Cited by 122 publications

References 30 publications

In vitro antioxidant, anti-diabetic and antilipemic potentials of quercetagetin extracted from marigold (Tagetes erecta L.) inflorescence residues

In vitro antioxidant, anti-diabetic and antilipemic potentials of quercetagetin extracted from marigold (Tagetes erecta L.) inflorescence residues

Application of Response Surface Methodology in Extraction of Bioactive Component from Palm Leaves (Elaeis guineensis)

Response Surface Optimization of Extraction and Antioxidant Activity of Total Flavonoids from Seed Shell of Juglans mandshurica

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