Response Surface Optimization of Extraction and Antioxidant Activity of Total Flavonoids from Seed Shell of Juglans mandshurica

Xu, Huaide; Bao, Yihong

doi:10.3136/fstr.20.715

Cited by 7 publications

(4 citation statements)

References 39 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…With respect to C. ovata seeds, some researchers have only reported that fatty acids in seed oil have an inhibitory effect on rodent colon cancer [23]. At present, the correlation study between antioxidant activities and the content of total flavonoids involving in sea buckthorn [24], pomegranate [25], Zanthoxylum bungeanum [26], Juglans mandshurica [27], Peanut [28], Garcinia kola Seeds [29], Rhynchosia volubilis [30], Oroxylum indicum [31], and Colored Chickpea [32] had been carried out. However, the phytosterols and tocopherols in C. ovata seed oil and the flavonoids in defatted seed meal as well as related activities were not reported.…”

Section: Introductionmentioning

confidence: 96%

Composition of Catalpa ovata Seed Oil and Flavonoids in Seed Meal as Well as Their Antioxidant Activities

Zhu

Dong

et al. 2015

J Americ Oil Chem Soc

View full text Add to dashboard Cite

In view of the growing demand for vegetable oil, currently exploration of some non‐conventional oils is of great concern. This study firstly analyzed the contents of fatty acids, phytosterols, and tocopherols in Catalpa ovata seed oil collected from four different Provinces in China. Then the composition of flavonoids as well as their antioxidant activities in defatted seed meal was determined. The results showed that the relative oil content in C. ovata seeds ranged from 24.0 to 36.0 % and seed oil was mainly composed of fatty acids linoleic acid (43.4–50.1 %), α‐linolenic acid (23.8–24.4 %), and oleic acid (13.1–16.2 %). The content of unsaturated fatty acids was up to 85.0 %. Sterol in seed oil mainly contained campesterol, stigmasterol, and β‐sitosterol. β‐sitosterol accounted for 74.0 % of the total sterol. The tocopherol content was 173.0–225.7 mg/100 g. Defatted seed meal from Hubei Province showed the highest content of total flavonoids (11 mg/g) and the strongest activities for DPPH radicals scavenging, ABTS radicals scavenging, and ferric reducing antioxidant power compared with other defatted seed meal in this study. Seven flavonoids were identified from C. ovata seed meal. These results suggest that C. ovata seeds may be developed as a new source of oil and can also be properly used in pharmaceuticals and cosmetics.

show abstract

Section: Introductionmentioning

confidence: 96%

Composition of Catalpa ovata Seed Oil and Flavonoids in Seed Meal as Well as Their Antioxidant Activities

Zhu

Dong

et al. 2015

J Americ Oil Chem Soc

View full text Add to dashboard Cite

show abstract

“…Ethanol aqueous was selected as the extraction solvent in this study because of its safety, easy accessibility and high affinity for antioxidants compared with other organic solvents [27,28,29]. Different ethanol concentrations had different polarities.…”

Section: Resultsmentioning

confidence: 99%

Extraction of Natural Antioxidants from the Thelephora ganbajun Mushroom by an Ultrasound-Assisted Extraction Technique and Evaluation of Antiproliferative Activity of the Extract against Human Cancer Cells

Zheng

Zhou

et al. 2016

IJMS

View full text Add to dashboard Cite

The Thelephora ganbajun mushroom has been found to be a potential rich source of natural antioxidants. In this study, an ultrasound-assisted extraction (UAE) technique together with GRAS (generally recognized as safe) solvents (ethanol and water) was used to maximize the extraction of antioxidants from Thelephora ganbajun. Five extraction parameters (ethanol concentration, solvent to solid ratio, extraction time, temperature and ultrasound power) were investigated by single-factor experiments, and then a central composite rotatable design was employed to study interaction of three key extraction parameters. The optimum conditions were as follows: 57.38% ethanol, 70.15 mL/g solvent to solid ratio, 10.58 min extraction time, 40 °C extraction temperature and 500 W ultrasound power. Under the optimum conditions, the antioxidant activity obtained was 346.98 ± 12.19 µmol Trolox/g DW, in accordance with the predicted value of 344.67 µmol Trolox/g DW. Comparison of UAE with conventional maceration and Soxhlet extraction, the UAE method showed stronger extract efficiency in a shorter extraction time. These results showed that UAE was an effective technique to extract antioxidants from Thelephora ganbajun. Furthermore, the extracts obtained under the optimized conditions exhibited antiproliferative activities toward human lung (A549), breast (MCF-7), liver (HepG2) and colon (HT-29) cancer cells, especially for liver and lung cancer cells. In addition, rutin, 2-hydrocinnamic acid and epicatechin were identified in the extract, which might contribute to antioxidant and antiproliferative activities.

show abstract

“…Due to the high solvent costs, the toxicity resulting from the solubility of the bioactive compounds in the solvent and low extraction efficiency, these solvents have been used regularly for the extraction of antioxidant compounds. Therefore, ethanol is one of the appropriate extraction solvents for antioxidant compounds due to its low cost, "green" characteristics, ease of access and safety for direct use in foods and pharmaceuticals (Xu & Bao 2014, Dailey & Vuong 2015.…”

Section: Introductionmentioning

confidence: 99%

OPTIMIZATION OF ULTRASONIC-ASSISTED EXTRACTION PARAMETERS FOR ANTIOXIDANTS FROM Curcuma longa L.

Şahin

2018

Trakya University Journal of Natural Sciences

View full text Add to dashboard Cite

In this study, ultrasonication was used to extract antioxidant compounds such as polyphenols, flavonoids, and curcuminoids from turmeric (Curcuma longa L.) The influences of time, ethanol concentration and temperature as three independent factors on the extraction of the total phenolic content were evaluated by the Folin-Ciocalteu method and the antioxidant capacities by the ABTS and chromium reducing antioxidant capacity (CHROMAC) methods. The central composite design (CCD) with a multi-response surface methodology (MRSM) was used for the statistical modeling of the response data followed by the regression and analysis of variance (ANOVA) to determine the significance of the model and the factors. The response predictions obtained at optimum extraction conditions of an extraction time of 64min, an ethanol concentration of 82% (v/v) and an extraction temperature of 32°C were 47.32mg GAE/g (for Folin-Ciocalteu), 29.15 (for ABTS) and 5.17mg TE/g (for CHROMAC). The predicted values obtained from the multi-response surface methodology agreed with the experimental values data 95% confidence level. These data indicate that the multi-response surface methodology is applicable for optimizing the ultrasonic-assisted extraction of antioxidant compounds from C. longa.

show abstract

Response Surface Optimization of Extraction and Antioxidant Activity of Total Flavonoids from Seed Shell of Juglans mandshurica

Abstract: The seed shell of Juglans mandshurica is a waste product from seed kernel processing in the food industry. For

Cited by 7 publications

References 39 publications

Composition of Catalpa ovata Seed Oil and Flavonoids in Seed Meal as Well as Their Antioxidant Activities

Composition of Catalpa ovata Seed Oil and Flavonoids in Seed Meal as Well as Their Antioxidant Activities

Extraction of Natural Antioxidants from the Thelephora ganbajun Mushroom by an Ultrasound-Assisted Extraction Technique and Evaluation of Antiproliferative Activity of the Extract against Human Cancer Cells

OPTIMIZATION OF ULTRASONIC-ASSISTED EXTRACTION PARAMETERS FOR ANTIOXIDANTS FROM Curcuma longa L.

Contact Info

Product

Resources

About