Optimization of chlorpheniramine maleate (CPM) delivery by response surface methodology – four component modeling using various response times and concentrations of chitosan-alanine, glutaraldehyde and CPM

Kumari, Kamlesh; Prasad, Kamlesh; Kundu, Patit Paban; Longowal, Sant

doi:10.3144/expresspolymlett.2009.27

Cited by 9 publications

(2 citation statements)

References 24 publications

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“…Therefore, temperature has an antagonistic effect on the response. 901094 response therefore the model is adequate representation of the data [29]. As represented in Table ANOVA, the difference between adjusted R 2 and predicted R 2 is < 0.2 and model adequacy precision is > 4 depicting a fit and adequate model [30].…”

Section: Anova and Model Representationmentioning

confidence: 92%

Optimization of Flexural Strength of Recycled Polyethylene-terephthalate (PET) Eco-Composite using Response Surface Methodology

et al. 2021

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Recycling and reuse of plastic waste by blending with virgin polymer has been affirmed to be the best way of managing the waste. Equally, agro-waste are best recycled than being burnt off. In the development of stronger and cheaper ecoefficient recycled PET composite for food packaging, this study focused on reinforcement of the blend of 20 wt. % recycled PET (rPET) and 80 wt. % virgin PET (vPET) with snail shell particulate and kenaf fiber via compression moulding process. The process parameters are fiber dosage, particulate dosage, moulding pressure and temperature. Box-Behnken design was engaged in the design of experiment and the samples were produced according to the experimental runs. Result of analysis of variance pinpointed the process factors as significant contributors to the flexural strength response. The model developed was validated to be significant and statistically fit. Interactions between the process variables as revealed by the response surface plots indicated the response was dependent on the interactive pattern between the variables. Response surface optimization showed an optimum flexural strength of 57.16 MPa was attainable at process parameters of 27.27 wt. %, 4.18 wt. %, 3.95 MPa, and 160 ˚C for fiber proportion, particulate proportion, moulding pressure and temperature respectively yielding 34.2 % improvement over the reference 80/20-vPET/rPET matrix. Model validation experiment undergone with the combined parameters and deviation of +0.036 was noted. Since the deviation is insignificant, the model is concluded to be statistically fit for predicting the flexural strength of the developed eco-composite.

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Section: Anova and Model Representationmentioning

confidence: 92%

Optimization of Flexural Strength of Recycled Polyethylene-terephthalate (PET) Eco-Composite using Response Surface Methodology

et al. 2021

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“…Response surface methodology (RSM) was adopted in the experimental design and analysis [45][46][47][48][49][50][51][52][53][54]. The experiments were conducted according to central composite rotatable design (CCRD) having two independent variables (k = 2) i.e.…”

Section: Experimental Design and Optimizationmentioning

confidence: 99%

Optimization of Flaked Rice Dry Roasting in Common Salt and Studies on Associated Changes in Chemical, Nutritional, Optical, Physical, Rheological and Textural Attributes

Kumar¹,

Prasad²

2017

Asian J. Chem.

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India is a leading paddy (Oryza sativa L.) producing country with a production of 157.20 MMT in the year 2014-15 from the crop area of 43.40 million hectare [1]. The contribution of India towards world paddy production is one fifth with a consolidated production figures of 22.69 ± 1.79 % and 20.71 ± 1.64 % for Asia and world, respectively. The trends of changes in the crop area and production figures for the paddy in India in comparison to the Asia and the world are depicted in Figs. 1 and 2. Asian countries produce more than 90 % paddy produced in the world. The edible monocotyledon, the starchy kernel obtained as rice from the processing of paddy available in abundance becomes a common staple food item of Asian people. Rice being a common food item of the region, therefore, rice based various ready to eat food relishes are produced locally at small or home scale levels [2-5]. Importance of physical properties in designing various food processing equipments for the purpose of harvesting, threshing, drying, handling, conveying, storage and aeration are very well recognized [6,7]. Our research on different characteristics of paddy to rice are reported elsewhere but associated research data for the development of technologies related to the mass productions of various rice based products are still lacking and not readily available [8-16].

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An overview on the mathematical modeling of hydrogels’ behavior for drug delivery systems

Caccavo

2019

International Journal of Pharmaceutics

109

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Optimization of chlorpheniramine maleate (CPM) delivery by response surface methodology – four component modeling using various response times and concentrations of chitosan-alanine, glutaraldehyde and CPM

Cited by 9 publications

References 24 publications

Optimization of Flexural Strength of Recycled Polyethylene-terephthalate (PET) Eco-Composite using Response Surface Methodology

Optimization of Flexural Strength of Recycled Polyethylene-terephthalate (PET) Eco-Composite using Response Surface Methodology

Optimization of Flaked Rice Dry Roasting in Common Salt and Studies on Associated Changes in Chemical, Nutritional, Optical, Physical, Rheological and Textural Attributes

An overview on the mathematical modeling of hydrogels’ behavior for drug delivery systems

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