Optimization for ultrasound-assisted extraction of polysaccharides with chemical composition and antioxidant activity from the Artemisia sphaerocephala Krasch seeds

Zheng, Quan; Ren, Daoyuan; Yang, Naibin; Yang, Xingbin

doi:10.1016/j.ijbiomac.2016.06.042

Cited by 50 publications

(31 citation statements)

References 34 publications

(39 reference statements)

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“…(B,C)). The positive effect of the extraction temperature could be explained by a higher diffusion coefficient of polysaccharides and enhancement of the solubility of polysaccharides in the extracting solvent as the temperature increases . In addition, at higher temperatures, mucilage viscosity decreased and the water‐soluble polysaccharides were more easily released, favoring the extraction yields .…”

Section: Resultsmentioning

confidence: 99%

“…Extraction time is a factor that could simultaneously influence the extraction efficiency and the quality of the obtained product. 14 In this regard, determination of extraction kinetics is important, since each product has a time requirement to achieve satisfactory extraction yields, which can affect quality parameters such as the antioxidant capacity of bioactive compounds. The extraction yield, total sugars, TPC and CT content quantified after 6 h of hot water extraction of DGSP are presented in Fig.…”

Section: Effect Of Time On Afe Extractionmentioning

confidence: 99%

“…Seed polysaccharides are widely known in terms of their structures and physico‐chemical properties, such as water retention capacity and antioxidant properties . These polysaccharides are often referred to as antioxidant fibers and have, in fact, been widely studied, with several alternative and simplified routes being proposed for their obtainment . However, few relevant studies have been conducted regarding grape seed antioxidant fiber.…”

Section: Introductionmentioning

confidence: 99%

“…10,11 These polysaccharides are often referred to as antioxidant fibers 12 and have, in fact, been widely studied, with several alternative and simplified routes being proposed for their obtainment. [13][14][15] However, few relevant studies have been conducted regarding grape seed antioxidant fiber.…”

Section: Introductionmentioning

confidence: 99%

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Grape seed pomace as a valuable source of antioxidant fibers

et al. 2019

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BACKGROUND Grape seed pomace is a valuable by‐product from winery/oil extraction industries and a potential source of bioactive compounds. Hot water extraction is the most widely used technology for polysaccharide recovery from plant and seed sources. To obtain an antioxidant fiber‐rich extract (AFE) from defatted grape seed pomace, seed:water ratio (1:10–1:20) and extraction temperature (70–90 °C) effects on extraction yield, total sugars, total phenolic compounds and condensed tannins were investigated. RESULTS The best extraction results were achieved at the highest seed:water ratio and temperature. At these conditions, the extraction yield and total sugar content of the freeze‐dried AFE were 100.1 g kg−1 and 725.3 g kg−1, respectively. The AFE presented high total phenolic content (16.2 g GAE kg−1), condensed tannins (515.1 mg CAT kg−1), soluble (219.1 g kg−1) and insoluble fibers (132.4 g kg−1), besides protein (171.1 g kg−1) and ash (152.6 g kg−1). The antioxidant capacity of the AFE was 382.7, 823.7 and 1439.4 μmol Trolox g−1 for DPPH, ABTS and ORAC methods. CONCLUSION The AFE was shown to be not only an interesting source of fiber with antioxidant capacity, which could become a potential foodstuff, but also an ecofriendly and sustainable alternative to use grape seed pomace. © 2019 Society of Chemical Industry

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Section: Resultsmentioning

confidence: 99%

Section: Effect Of Time On Afe Extractionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Grape seed pomace as a valuable source of antioxidant fibers

et al. 2019

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“…The presence of reducing agent such as polysaccharides would result in the transformation from Fe 3+ to Fe 2+ by donating an electron, reducing them into more stable and unreactive species [22]. Meanwhile, the reaction mixture turned yellow to blue as a result of the formation of Perl's Prussian blue, which can be monitored at 700 nm [23]. Figure 4(a) shows the reducing power of crude TFP, TFPI, and ascorbic acid (Vc, positive control) of varied concentrations.…”

Section: Resultsmentioning

confidence: 99%

Polysaccharides fromTrichosanthes Fructusvia Ultrasound-Assisted Enzymatic Extraction Using Response Surface Methodology

Chen

Shen

et al. 2017

BioMed Research International

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An efficient procedure for ultrasound-assisted enzymatic extraction of crude polysaccharides from Trichosanthes Fructus (crude TFP) using response surface methodology (RSM) was developed. The Box–Behnken design was applied to optimize the effects of pH (X1), enzyme amount (X2), extraction temperature (X3), and liquid-to-solid ratio (X4) on the extraction. The statistical analysis indicated that the independent variables (X4, X2, and X3), the quadratic coefficients (X12, X22, X32, and X42), and the interaction coefficient (X1X3) had significant impact on the yield of crude TFP. The optimal conditions were determined as follows: pH 4.5, enzyme amount 5000 u/g, extraction temperature 45°C, and liquid-to-solid ratio 30 ml/g. The experimental yield of crude TFP was 6.58%, which was very close to the predicted yield of 6.71%. TFPI was then purified and characterized with Sephadex G-100 column, UV-Vis, GPC, and FT-IR. The average molecular weight of TFPI was calculated to be 1.49 × 105 Da. TFPI exhibited strong reducing power and possessed not only remarkable scavenging activities against ABTS•+ and DPPH radicals, but also high antitumor activities in C4-2, DU145, and PC3 cells. The results suggest that Trichosanthes Fructus and TFPI could be a novel potent natural medicine with antioxidant and antitumor activities.

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Antioxidant and hepatoprotective effects of novel heteropolysaccharide isolated from Lobularia maritima on CCl4‐induced liver injury in rats

Hsouna

Hfaiedh

Slima

et al. 2022

Food Science & Nutrition

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The aim of the present study was to investigate the extraction and the characterization of a novel heteropolysaccharide from Tunisian halophyte Lobularia maritima (LmPS). We were also interested in its antioxidant, anti‐inflammatory, and hepatoprotective effects on carbon tetrachloride (CCl4)‐induced liver injury in rats. LmPS physicochemical properties were evaluated by thin‐layer chromatography (TLC), high‐performance liquid chromatography (HPLC), thermogravimetric analysis (TGA), and UV absorption. According to TLC and HPLC results, LmPS was a heteropolysaccharide composed of glucose, galactose, and xylose. Its molecular weight was 130.62 kDa. This heteropolysaccharide was characterized by a significant antioxidant potential and was efficient against oxidative stress and CCL4‐induced hepatotoxicity in rat Wistar models (n = 8) treated with a single dose of LmPS 250 mg/kg of body weight. This was evidenced by a significant increase in serum marker enzymes specially aspartate transaminase (AST), alanine transaminase (ALT), alkaline phosphatase (ALP), and lactate dehydrogenase (LDH). The cytokines released after stimulation of rats with LmPS showed high anti‐inflammatory profiles with an increased rate of interleukine‐10 (IL‐10) with 0.03 pg/mL compared to animals treated only with CCl4. On the contrary, we noticed a decrease of the other cytokines (tumor necrosis factor α: TNF‐α, interleukine‐6: IL‐6, transforming growth factor beta 1: TGF‐β1) with average concentration values of <0.2, 0.1, and 0.04 pg/mL, respectively. Besides, histopathological examinations revealed that CCl4 causes acute liver damage, characterized by extensive hepatocellular necrosis, vacuolization, and inflammatory cell infiltration, as well as DNA fragmentation. LmPS administration at a dose of 250 mg/kg resulted in a significant hepatoprotection, evidenced by a reduction of CCl4‐induced oxidative damage for all tested markers. These findings eagerly confirmed that LmPS was effective in the protection against CCl4‐induced hepatotoxicity and genotoxicity. It, therefore, suggested a potential therapeutic use of this polysaccharide as an alternative medicine for patients with acute liver diseases.

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Optimization for ultrasound-assisted extraction of polysaccharides with chemical composition and antioxidant activity from the Artemisia sphaerocephala Krasch seeds

Cited by 50 publications

References 34 publications

Grape seed pomace as a valuable source of antioxidant fibers

Grape seed pomace as a valuable source of antioxidant fibers

Polysaccharides fromTrichosanthes Fructusvia Ultrasound-Assisted Enzymatic Extraction Using Response Surface Methodology

Antioxidant and hepatoprotective effects of novel heteropolysaccharide isolated from Lobularia maritima on CCl4‐induced liver injury in rats

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