Optimal time for predicting myocardial viability after successful primary angioplasty in acute myocardial infarction: a study using myocardial contrast echocardiography

Sakuma, Tadamichi; Otsuka, Masaya; Okimoto, Tomokazu; Fujiwara, Hitoshi; Sumii, Kotaro; Imazu, Michinori; Hayashi, Yasuhiko

doi:10.1016/s0002-9149(00)01484-3

Cited by 37 publications

(20 citation statements)

References 21 publications

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“…We found as much as 46% of ESRD patients who had significant coronary artery stenoses which is comparable with previous reports [20, 25]. Despite the known limitations, we used TFC as an angiographic marker of myocardial perfusion.…”

Section: Discussionsupporting

confidence: 87%

See 1 more Smart Citation

Application of Myocardial Contrast Echocardiography for the Perfusion Assessment in Patients with End-Stage Renal Failure – Comparison with Coronary Angiography

Sobkowicz

Tomaszuk‐Kazberuk²,

Kralisz³

et al. 2008

Am J Nephrol

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Section: Discussionsupporting

confidence: 87%

“…Recently this technique was applied for perfusion exploration, particularly after myocardial infarction [20]. In this setting, MCE provides information concerning infarct extension, no-reflow phenomenon and tissue viability.…”

Section: Discussionmentioning

confidence: 99%

Application of Myocardial Contrast Echocardiography for the Perfusion Assessment in Patients with End-Stage Renal Failure – Comparison with Coronary Angiography

Sobkowicz

Tomaszuk‐Kazberuk²,

Kralisz³

et al. 2008

Am J Nephrol

View full text Add to dashboard Cite

“…Contrast echocardiography has previously been validated as a reference technique for the evaluation of myocardial perfusion (1,(25)(26)(27). The most significant advantage is that it can be applied in the setting of AMI.…”

Section: Discussionmentioning

confidence: 99%

Myocardial perfusion assessed by contrast echocardiography correlates with angiographic perfusion parameters in patients with a first acute myocardial infarction successfully treated with angioplasty

Tomaszuk‐Kazberuk

Sobkowicz

Kamiński

et al. 2008

Canadian Journal of Cardiology

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“…echocardiography for predicting myocardial viability might be 1 day after revascularization, most of the infarcted myocardial prognosis might be determined just after the coronary revascularization therapy. [18][19][20][21] Therefore, the plain chest CT just after coronary revascularization could be useful in predicting the left ventricular systolic and diastolic function in the remote period after MI. More effective methods of reducing the coronary microcirculatory damage within 24 h after coronary revascularization are needed.…”

Section: Discussionmentioning

confidence: 99%

Plain Computed Tomography for Assessment of Early Coronary Microcirculatory Damage After Revascularization Therapy in Acute Myocardial Infarction

Kato

Dote

Sasaki

et al. 2006

Circ J

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yocardial salvage after reperfusion may be limited by deleterious changes in the microcirculation of the previously ischemic tissue, 1 which can result in a progressive decrease of capillary blood flow to potentially viable myocytes (no-reflow phenomenon) in acute myocardial infarction (MI). 2 Previous studies using an intracoronary Doppler guidewire demonstrated that the coronary flow velocity pattern measured immediately after successful revascularization is predictive of the recovery of regional and global left ventricular function in patients with acute MI. 3,4 Furthermore, myocardial contrast echocardiography can independently detect microcirculatory damage and myocardial viability early after acute MI. [5][6][7] Recently, computed tomography (CT) has been used to evaluate the myocardial perfusion in stable angina or acute coronary syndrome. 8,9 A previous experimental study in a canine model demonstrated that both progression of the contrast defect area in myocardial contrast echocardiography with a gradual thickening of the wall and an enhancement of myocardial area detected by CT just after reperfusion are charCirculation Journal Vol. 70, November 2006 acteristic of hemorrhagic infarction. 10,11 The aim of the present study was to clarify the relationship between the microcirculatory impairment and prolonged enhancement of reperfused myocardium after successful revascularization in acute MI. Methods Patient Population and Study DesignThirteen consecutive patients (11 men, 2 women), aged from 45 to 79 years (mean age: 67±12 years), who suffered their first acute anterior MI were enrolled in the study. The diagnosis of acute MI was made on the basis of chest pain lasting for over 30 min, ST elevation of at least 2 mm in 2 adjacent leads on the electrocardiogram, and an increase of serum creatine kinase (CK) to more than twice the normal upper limit. Each patient had complete occlusion or severe stenotic lesion of the proximal or middle segment of the left anterior descending artery (LAD) on emergency coronary angiography, and underwent successful percutaneous coronary intervention (PCI) within 6 h after the onset of symptoms. The coronary blood flow velocity pattern and coronary flow velocity reserve in the LAD were measured immediately after PCI using a Doppler guidewire in 13 patients. All patients underwent chest CT immediately after successful revascularization. The left ventricular ejection fraction (LVEF) and left ventricular end-diastolic volume (LVEDV) Background Coronary microcirculatory damage is an important factor for the prognosis for acute myocardial infarction (MI) after revascularization. The myocardial enhancement area with contrast media infused during coronary revascularization therapy, detected by computed tomography (CT) just after revascularization, has been reported to correspond to the area of hemorrhagic infarction. The relationship between myocardial contrast enhancement and coronary microcirculatory damage was investigated in the present study. Methods and ResultsThirteen pati...

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Optimal time for predicting myocardial viability after successful primary angioplasty in acute myocardial infarction: a study using myocardial contrast echocardiography

Cited by 37 publications

References 21 publications

Application of Myocardial Contrast Echocardiography for the Perfusion Assessment in Patients with End-Stage Renal Failure – Comparison with Coronary Angiography

Application of Myocardial Contrast Echocardiography for the Perfusion Assessment in Patients with End-Stage Renal Failure – Comparison with Coronary Angiography

Myocardial perfusion assessed by contrast echocardiography correlates with angiographic perfusion parameters in patients with a first acute myocardial infarction successfully treated with angioplasty

Plain Computed Tomography for Assessment of Early Coronary Microcirculatory Damage After Revascularization Therapy in Acute Myocardial Infarction

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