Application of Myocardial Contrast Echocardiography for the Perfusion Assessment in Patients with End-Stage Renal Failure – Comparison with Coronary Angiography

Sobkowicz, Bożena; Tomaszuk‐Kazberuk, Anna; Kralisz, Paweł; Małyszko, Jolanta; Kalinowski, M; Hryszko, Tomasz; Małyszko, J.; Dobrzycki, Sławomir; Musiał, Włodzimierz J.

doi:10.1159/000141936

Cited by 4 publications

(3 citation statements)

References 51 publications

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“…Therefore, according to a recent expert consensus report from 2012, "noninvasive stress testing may be considered in kidney transplantation candidates with no active cardiac conditions based on the presence of multiple CAD risk factors regardless of functional status" and "routine noninvasive screening of patients and to assess the rate, results of revascularization, and mortality in this particular population. 47,48 As reported previously, revascularization did not improve patient's survival. 49 Moreover, there was no significant difference between the overall 3-year mortality among those who underwent invasive procedures and mortality in the group with significant CAD treated conservatively.…”

Section: Cardiac Evaluation Of Kidney Transplant Recipientsmentioning

confidence: 60%

“…45 Myocardial contrast echocardiography (MCE) is a bedside technique recently applied for the assessment of myocardial perfusion as well as in patients with ESRD. [46][47][48] Real-time MCE was also evaluated as a tool to select candidates for coronary revascularization among patients with ESRD prolonged duration of CKD, and dialysis vintage longer than 1 year. 5,10, 39 Guidelines and position papers developed by national organizations can serve as useful tools for informing cardiac evaluation practices before noncardiac surgery.…”

Section: Cardiac Evaluation Of Kidney Transplant Recipientsmentioning

confidence: 99%

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Cardiovascular disease and kidney transplantation‑evaluation of potential transplant recipient

Małyszko¹,

Bachórzewska−Gajewska²,

Tomaszuk‐Kazberuk³

et al. 2014

Polish Archives of Internal Medicine

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Nowadays, from 50% to 60% of deaths can be directly attributed to CVD, with an incidence of ischemic heart disease being approximately 1 per 100 person-years at risk. 3 In contrast, some older studies reported that between 17% and 50% of deaths in kidney transplant recipients were due to CVD. 4 Moreover, CVD is the most common cause of death in kidney allograft recipients with a functioning graft, and accounts for 30% of overall graft loss from death, with the greatest rates in Cardiovascular disease and kidney disease Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in patients on renal replacement therapy, including kidney transplant recipients. 1 Death from CVD is also the most common cause of graft loss. 2 Mortality associated with kidney transplantation decreased significantly in the 1960s and 1980s owing to a reduction in the incidence of infection-related deaths, 2 while cardiovascular mortality increased.

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Section: Cardiac Evaluation Of Kidney Transplant Recipientsmentioning

confidence: 60%

Section: Cardiac Evaluation Of Kidney Transplant Recipientsmentioning

confidence: 99%

Cardiovascular disease and kidney transplantation‑evaluation of potential transplant recipient

Małyszko¹,

Bachórzewska−Gajewska²,

Tomaszuk‐Kazberuk³

et al. 2014

Polish Archives of Internal Medicine

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“…In patients with ESRD utility of MCE was previously investigated only by our group. 18,19 According to our studies, MCE was a safe and useful diagnostic tool in establishing diagnosis of coronary artery disease in patients with ESRD. Moreover, MCE facilitated the decision for coronary angiography.…”

Section: Discussionmentioning

confidence: 82%

Left ventricular morphology and function in diabetic and nondiabetic hemodialyzed patients

Tomaszuk‐Kazberuk

Małyszko

Bachórzewska−Gajewska

et al. 2011

Hemodialysis International

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Morbidity in end-stage renal disease (ESRD) diabetic patients is worse than in patients without diabetes mellitus (DM). This study aims to compare clinical, laboratory, and echocardiographic features between the ESRD patients with and without DM. Fifty-eight ESRD patients on dialysis were prospectively divided into two groups according to the presence of DM. Demographic, clinical, laboratory, and echocardiographic features (ejection fraction and wall motion score index) were compared between the two groups. Overall, 20 out of 58 patients (37.8%) with ESRD had DM. There were no significant differences between the patients with DM and those without DM when it comes to age (60.6 ± 10.6 vs. 59.0 ± 10.6 years, P = 0.665), ejection fraction (52.6% ± 12.8% vs. 54.2% ± 12.8%, P = 0.59), and wall motion score index (1.21 ± 0.3 vs.1.15 ± 0.3, P = 0.37). In multivariant analysis of the interventricular septum, posterior wall thickness and left atrium size correlated positively with DM. There was also no statistical difference in myocardial perfusion disturbances on real-time contrast echocardiography between the groups with and without DM (12 (60%) patients vs. 14 patients (36.8%), P = 0.079). Among diabetics 77.8% had significant atherosclerotic changes, while in the group without DM, only 38.1%, P = 0.01. From the laboratory parameters ferritin and high-sensitivity C-reactive protein levels were significantly higher in the group with DM, P = 0.014 and P = 0.026, respectively. Patients with ESRD and DM have significantly bigger left atrial size, thicker left ventricular walls, and higher serum ferritin and high-sensitivity C-reactive protein levels than the patients without DM. The aforementioned features may be possible risk factors for the development of adverse cardiac events in patients on hemodialysis.

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Real-time myocardial contrast echocardiography as a useful tool to select candidates for coronary revascularization among patients with end-stage renal disease – a 3-year follow-up study

Tomaszuk‐Kazberuk

Sobkowicz

Malyszko

et al. 2011

Advances in Medical Sciences

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Application of Myocardial Contrast Echocardiography for the Perfusion Assessment in Patients with End-Stage Renal Failure – Comparison with Coronary Angiography

Cited by 4 publications

References 51 publications

Cardiovascular disease and kidney transplantation‑evaluation of potential transplant recipient

Cardiovascular disease and kidney transplantation‑evaluation of potential transplant recipient

Left ventricular morphology and function in diabetic and nondiabetic hemodialyzed patients

Real-time myocardial contrast echocardiography as a useful tool to select candidates for coronary revascularization among patients with end-stage renal disease – a 3-year follow-up study

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