Cardiovascular disease and kidney transplantation‑evaluation of potential transplant recipient

Abstract

Nowadays, from 50% to 60% of deaths can be directly attributed to CVD, with an incidence of ischemic heart disease being approximately 1 per 100 person-years at risk. 3 In contrast, some older studies reported that between 17% and 50% of deaths in kidney transplant recipients were due to CVD. 4 Moreover, CVD is the most common cause of death in kidney allograft recipients with a functioning graft, and accounts for 30% of overall graft loss from death, with the greatest rates in Cardiovascular disease and kidney disease Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in patients on renal replacement therapy, including kidney transplant recipients. 1 Death from CVD is also the most common cause of graft loss. 2 Mortality associated with kidney transplantation decreased significantly in the 1960s and 1980s owing to a reduction in the incidence of infection-related deaths, 2 while cardiovascular mortality increased.

Evaluation of Atrial Electromechanical Delay to Predict Atrial Fibrillation in Hemodialysis Patients

“…The prevalence of atrial fibrillation (AF) in patients with chronic renal failure undergoing hemodialysis is 2–3 times higher than the general population [ 1 , 2 , 3 , 4 , 5 ]. Hemodialysis patients are closely associated with the risk factors for the development of AF such as aging, hypertension, diabetes mellitus, coronary artery disease, and heart failure.…”

Do patients with a history of systemic embolism have better compliance in International Normalized Ratio control?

“…Although NOACs are nowadays the preferred therapeutic option according to European Society of Cardiology guidelines, patients with markedly reduced renal function, especially with eGFR < 30 ml/min, benefit from VKA treatment [35] . Also patients after kidney transplantation are limited to use of VKA [36,37,38] . From AF -atrial fibrillation Table 3.…”

Comorbidities on kidney transplantation waiting list relative to the status of the potential recipient

“…In addition, some patients, in particular with diabetes, may require either percutaneous coronary intervention (PCI) or cardiac artery bypass grafting (CABG). Thus as reviewed previously, cardiovascular evaluation of potential kidney allograft recipients is of utmost importance [ 16 ]. A meta-analysis suggested that the strategy of CABG is better than PCI with DES for diabetic patients with multivessel CAD [ 17 ].…”