Myocardial perfusion assessed by contrast echocardiography correlates with angiographic perfusion parameters in patients with a first acute myocardial infarction successfully treated with angioplasty

Tomaszuk‐Kazberuk, Anna; Sobkowicz, Bożena; Kamiński, Karol; Gugała, Kamil; Mężyński, Grzegorz; Dobrzycki, Sławomir; Lewczuk, Anna; Kazberuk, Waldemar; Musiał, Włodzimierz J.

doi:10.1016/s0828-282x(08)70652-4

Cited by 19 publications

(13 citation statements)

References 33 publications

(28 reference statements)

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“…Interestingly, another study directly compared MCE and angiographic TIMI myocardial perfusion grade scores in 100 patients undergoing PPCI and the authors found a significant correlation between MCE scores and TIMI myocardial perfusion grade scores [130]. More recently, angiographic indexes of myocardial reperfusion have been associated with the quantification of microvascular obstruction areas, as assessed by CMR.…”

Section: Diagnosis In the Cath-lab: Angiographic And Doppler Indexesmentioning

confidence: 99%

Microvascular Obstruction After Primary Percutaneous Coronary Intervention: Pathogenesis, Diagnosis and Prognostic Significance

Niccoli

Cosentino

Minelli

et al. 2013

Current Vascular Pharmacology

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The primary goal in reopening an infarct-related artery is the restoration of myocardial tissue-level perfusion. In a variable proportion of patients with ST-elevation myocardial infarction, however, microcirculatory impairment may persist after epicardial coronary artery recanalization. This phenomenon is known as microvascular obstruction (MVO). Ischemic injury, reperfusion injury, and distal embolization along with the individual response to each of these mechanisms are variably involved in the pathogenesis of MVO in the single patient. Importantly, MVO is associated with a worse prognosis both at short- and long-term follow-up. MVO can be assessed in the cath-lab by simple angiographic indexes, such as Thrombolysis in Myocardial Infarction grade score and Myocardial Blush Grade, or by invasive measures of coronary flow pattern. Imaging techniques, such as myocardial contrast echocardiography or cardiac magnetic resonance, and ST-segment resolution on standard electrocardiogram are used in the days following reperfusion with the patient in the coronary care unit. In this article, we review the available data regarding pathogenesis, diagnosis and the prognostic significance of MVO after primary percurtaneous coronary intervention in ST-elevation myocardial infarction patients, with a brief highlighting on the crucial role of its prevention and its early detection.

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Section: Diagnosis In the Cath-lab: Angiographic And Doppler Indexesmentioning

confidence: 99%

Microvascular Obstruction After Primary Percutaneous Coronary Intervention: Pathogenesis, Diagnosis and Prognostic Significance

Niccoli

Cosentino

Minelli

et al. 2013

Current Vascular Pharmacology

View full text Add to dashboard Cite

show abstract

“…Moreover, authors of the latter paper [1], have reported almost 60% incidence of signs and symptoms of congestive HF within 6 months after AMI in patients in whom myocardial perfusion was inadequate (MBG 0 and 1) after primary coronary angioplasty. There are also contradictory data and several small studies have reported the lack of correlation between MBG and myocardial perfusion assessed by contrast echocardiography [8,9]. Furthermore, Bertomeu--Gonzalez et al [10] have raised the question on inter-observer variability of MBG assessment, have reported on a lack of correlation between MBG and LVEF assessed with magnetic resonance imaging (MRI).…”

Section: Introductionmentioning

confidence: 99%

Quantitative myocardial blush score (QuBE) allows the prediction of heart failure development in long-term follow-up in patients with ST-segment elevation myocardial infarction: Proof of concept study

et al. 2019

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“…6,7) Until recently, the coronary microcirculation has been evaluated by contrast echocardiography, 8) radionucleide imaging, 9) magnetic resonance imaging, 10) computed tomography, 11) electron beam computed tomography, 12) pressure wire, 13) Doppler guidewire, 14) coronary angiography 15) and left ventricular pressure. 16) These techniques can evaluate coronary microcirculation as a whole, but functional evaluation of the individual microvessels has been beyond the scope of these imaging modalities.…”

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confidence: 99%

Cardioscopic Observation of Subendocardial Microvessels in Patients With Coronary Artery Disease

et al. 2011

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SummaryCoronary microvessels play a direct and critical role in determining the extent and severity of myocardial ischemia and cardiac function. However, because direct observation has never been performed in vivo, the functional properties of the individual microvesssels in patients with coronary artery disease remain unknown.Subendocardial coronary microvessels were observed by cardioscopy in 149 successive patients with coronary artery disease (81 with stable angina and 68 with old myocardial infarction).Twenty-four arterial microvessels (AMs) and 27 venous microvessels (VMs) were observed in the left ventricular subendocardium. All 12 AMs and 13 of 14 VMs that were located in normokinetic-to-hypokinetic left ventricular wall segments were filled with blood during diastole and were collapsed during systole. In contrast, 8 of 12 AMs and 9 of 13 VMs that were located in akinetic-to-dyskinetic wall segments were filled with blood during systole and were collapsed during diastole. There were no significant correlations between the timing of blood filling and the severity of coronary stenosis and collateral development.In patients with coronary artery disease, the timing of blood filling of AMs and VMs was dependent on the regional left ventricular contractile state; during diastole when contraction was preserved and during systole when it was not. It remains to be elucidated whether and how blood filling is disturbed in other categories of heart disease. (Int Heart J 2011; 52: 274-279)

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Myocardial perfusion assessed by contrast echocardiography correlates with angiographic perfusion parameters in patients with a first acute myocardial infarction successfully treated with angioplasty

Cited by 19 publications

References 33 publications

Microvascular Obstruction After Primary Percutaneous Coronary Intervention: Pathogenesis, Diagnosis and Prognostic Significance

Microvascular Obstruction After Primary Percutaneous Coronary Intervention: Pathogenesis, Diagnosis and Prognostic Significance

Quantitative myocardial blush score (QuBE) allows the prediction of heart failure development in long-term follow-up in patients with ST-segment elevation myocardial infarction: Proof of concept study

Cardioscopic Observation of Subendocardial Microvessels in Patients With Coronary Artery Disease

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