Optical fiber aptasensor for label-free bacteria detection in small volumes

Janik, Monika; Brzozowska, Ewa; Czyszczoń, Paula; Celebańska, Anna; Koba, Marcin; Gamian, Andrzej; Bock, Wojtek J.; Śmietana, Mateusz

doi:10.1016/j.snb.2020.129316

Cited by 51 publications

(22 citation statements)

References 49 publications

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“…However, with the reported LOD value, the biosensor can detect E. coli O157:H7 at concentrations lower than the infection dose. A fully optical transducer system for the detection of E. coli was studied by Janik et al [33] . The developed optical fiber device utilized a sensing mechanism based on microcavity in-line Mach-Zehnder interferometer.…”

Section: Biosensors For the Detection Of Pathogensmentioning

confidence: 99%

Recent advances in the biosensors application for the detection of bacteria and viruses in wastewater

Kadadou¹,

Tizani²,

Wadi³

et al. 2022

Journal of Environmental Chemical Engineering

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Section: Biosensors For the Detection Of Pathogensmentioning

confidence: 99%

Recent advances in the biosensors application for the detection of bacteria and viruses in wastewater

Kadadou¹,

Tizani²,

Wadi³

et al. 2022

Journal of Environmental Chemical Engineering

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“…Examples of BOFS for pH and oxygen detection can be found in Section 3.2.1 and Section 3.2.2 , respectively, whereas those for cancer detection and diagnosis are presented in Section 3.2.3 . In addition, the detection of other diverse biochemical parameters has been recently reported and will be detailed in Section 3.2.4 [ 63 , 64 , 65 , 66 , 67 , 68 , 69 , 70 , 71 , 72 ].…”

Section: Advances In Optical-fibre-based Biomedical Photonic Sensorsmentioning

confidence: 99%

“…Finally, an optical-fibre aptasensor (ELISA-like sensor) using an in-line microcavitity MZI was developed by Janik et al using fs-laser processing [ 68 ]. The sensor used peptide aptamers as bioreceptors to measure E. coli O157:H7.…”

Section: Advances In Optical-fibre-based Biomedical Photonic Sensorsmentioning

confidence: 99%

Recent Advances in Biomedical Photonic Sensors: A Focus on Optical-Fibre-Based Sensing

Ochoa

Algorri

Roldán-Varona

et al. 2021

Sensors

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In this invited review, we provide an overview of the recent advances in biomedical photonic sensors within the last five years. This review is focused on works using optical-fibre technology, employing diverse optical fibres, sensing techniques, and configurations applied in several medical fields. We identified technical innovations and advancements with increased implementations of optical-fibre sensors, multiparameter sensors, and control systems in real applications. Examples of outstanding optical-fibre sensor performances for physical and biochemical parameters are covered, including diverse sensing strategies and fibre-optical probes for integration into medical instruments such as catheters, needles, or endoscopes.

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“…The sensitivity of the system has been investigated with the use of the thin layer deposition [31]. Although the µIZMI has been reported for different applications, such as bacteria detection [32,33], and real-time monitoring of isothermal DNA amplification [34], the subject of using the in-fiber sensing structures for multi-domain measurements has never been addressed or studied in the literature reported so far.…”

Section: Introductionmentioning

confidence: 99%

Electrochemistry in an Optical Fiber Microcavity - Optical Monitoring of Electrochemical Processes in Picoliter Volumes

Gabler¹,

Krześniak²,

Janik³

et al. 2021

Preprint

Self Cite

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In this work, we demonstrate a novel method for multi-domain analysis of properties of analytes in volumes as small as picoliter, combining electrochemistry and optical measurements. A microcavity in-line Mach-Zehnder interferometer (µIMZI) obtained in a standard single-mode optical fiber using femtosecond laser micromachining was able to accommodate a microelectrode and optically monitor electrochemical processes inside the fiber. The interferometer shows exceptional sensitivity to changes in optical properties of analytes in the microcavity. We show that the optical readout follows the electrochemical reactions. Here, the redox probe (ferrocenedimethanol) undergoing reactions of oxidation and reduction changes the optical properties of the analyte (refractive index and absorbance) that are monitored by the µIMZI. Measurements have been supported by numerical analysis of both optical and electrochemical phenomena. On top of a capability of the approach to perform analysis in microscale, the difference between oxidized and reduced forms in the near-infrared can be clearly measured using the µIMZI, which is hardly possible using other optical techniques. The proposed multi-domain concept is a promising approach for highly reliable and ultrasensitive chemo- and biosensing.

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Optical fiber aptasensor for label-free bacteria detection in small volumes

Cited by 51 publications

References 49 publications

Recent advances in the biosensors application for the detection of bacteria and viruses in wastewater

Recent advances in the biosensors application for the detection of bacteria and viruses in wastewater

Recent Advances in Biomedical Photonic Sensors: A Focus on Optical-Fibre-Based Sensing

Electrochemistry in an Optical Fiber Microcavity - Optical Monitoring of Electrochemical Processes in Picoliter Volumes

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