Optical Coherence Tomography Angiography of Polypoidal Neovascularization Associated with Choroidal Nevus

Abstract

Purpose To report a case of juxtapapillary polypoidal choroidal neovascularization (PCNV) associated with choroidal nevus investigated by means of optical coherence tomography angiography (OCT-A). Methods Case report. Results A 72-year-old woman presented with visual loss and metamorphopsia in her left eye for 5 days secondary to PCNV that developed on the border of a juxtapapillary choroidal nevus. Fluorescein angiography, indocyanine green angiography, and spectral-domain OCT confirmed the diagnosis. En face OCT-A disclosed a large tangled hyperreflective PCNV spreading from the optic disc at different levels of the choriocapillaris; the polyp lumina appeared hyporeflective. The patient was treated with 3 intravitreal injections of anti-vascular endothelial growth factor with partial functional recovery. Conclusions Our case showed the application of OCT-A in the diagnosis of a case of active PCNV complicating a benign intraocular tumor.

Optical coherence tomography angiography in quiescent choroidal neovascularization associated with choroidal nevus: 5 years follow-up

“…4,5 Multimodal imaging and in particular the OCTA allowed to identify the features of the active CNV, showing its size and the shape. 5,8 Our case reported the presence of a quiescent CNV after a long-term follow-up probably due to the alteration and disruption of the RPE-Bruch membrane complex overlying the nevus. 9 The localization of the quiescent CNV in macular region highlights the importance of an early and precise diagnosis.…”

Optical coherence tomography angiography (OCTA) applications in ocular oncology

“…Cicinelli et al discussed a case of polypoidal with a concomitant peripapillary nevus. The OCTA en face imaging revealed the irregular branching of the new vessels and the hyporeflective areas corresponding to hyalinized polyps with the dimensions of the lesion appearing larger in OCTA than FA and ICGA [ 33 ]. A larger retrospective case series by Pellegrini et al also illustrated that the sensitivity of OCTA in the disclosure of CNV associated with nevus is more than FA and ICG imaging (100% vs. 90% and 83%, respectively) [ 34 ].…”