Optical Coherence Tomography Angiography Findings in Dengue-Related Maculopathy: A Case Report

Abstract

100 words (93 words)The ophthalmic manifestations of dengue fever include a visually impairing maculopathy, where patients are left with a central or paracentral relative scotoma. We present a case of a 26-year old female patient returning from Thailand with unilateral reduction in visual acuity and a central scotoma associated with dengue fever. We report the use of the OCTA as a non-invasive imaging platform to demonstrate its value in showing the persistent changes corresponding to the functional central scotoma in dengue-related maculopathy, which often cannot be visualised clinically, or by standard OCT and fundus fluorescein angiography. Introduction:

<p>Retinal Vasculitis with Macular Infarction: A Dengue-related Ophthalmic Complication</p>

“… 11 , 12 OCT angiography study in a case of dengue-related maculopathy has revealed loss of capillaries in the superficial and deep capillary plexus. 15 Sharief et al found macular ischemia to increase the risk of vision loss in vasculitis eyes, 11 similar to our patient who developed macular infarction leading to irreversible loss of vision.…”

Optical coherence tomography angiography features of acute macular neuroretinopathy in dengue fever

“…In a recent case, retinal microvascular changes were demonstrated using OCTA in a patient with dengue fever with no clinically appreciable fundus lesions. [ 10 ] However, our patient shows features of AMN clinically, on imaging and OCTA without much change in ischemia at 6-month follow-up.…”

Multimodal Imaging in Dengue-Fever-Associated Maculopathy

“…11,18 A recent case study demonstrated an irregularly enlarged foveal avascular zone with persistent loss of internal and external retinal plexus capillaries on OCT angiography, suggesting a vascular mechanism for the neural loss and persistence of scotoma. 19 Multimodal imaging is thus necessary to better understand the extent of macular involvement in dengue-associated maculopathy.…”