Opening windows on new biology and disease mechanisms: development of real-time
            <i>in vivo</i>
            sensors

Eckert, Mark A.; Zhao, Weian

doi:10.1098/rsfs.2013.0014

Cited by 8 publications

(2 citation statements)

References 43 publications

(67 reference statements)

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“…First, nucleic acids are susceptible to in vivo environments, e.g., degradation by ubiquitous nucleases and aggregation with plasma proteins; this can be a critical impediment to applications in in vivo imaging and sensing. 165 Second, the small size of aptamers sometimes can be disadvantageous; renal filtration and rapid clearance from the bloodstream can also impede their use in vivo. 166 Third, the aptamer generation is not easy; current SELEX technologies that are usually time-consuming and labor-intensive have an unsatisfactory success rate in discovery.…”

Section: Discussionmentioning

confidence: 99%

Detection and beyond: challenges and advances in aptamer-based biosensors

Yoo

2020

Mater. Adv.

173

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Section: Discussionmentioning

confidence: 99%

Detection and beyond: challenges and advances in aptamer-based biosensors

Yoo

2020

Mater. Adv.

173

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“…In vivo nanosensing systems [43], which can operate inside the human body in real time, have been recently proposed as a way to provide faster and more accurate disease diagnosis and treatment than traditional technologies based on in vitro medical devices. However, the sensing range of each nanosensor is limited to its close nano-environment; thus, many nanosensors are needed to cover significant regions or volumes.…”

Section: In Vivo Nano-communicationmentioning

confidence: 99%

In Vivo WBAN Communication: Design and Implementation

Elayan¹,

Shubair²,

Almoosa³

2018

Preprint

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The emerging in vivo communication and networking system is a prospective component in advancing healthcare delivery and empowering the development of new applications and services. In vivo communications is based on networked cyber-physical systems of embedded devices to allow rapid, correct and costeffective responses under various conditions. This chapter presents the existing research which investigates the state of art of the in vivo communication. It focuses on characterizing and modeling the in vivo wireless channel and contrasting it with the other familiar channels. MIMO in vivo is also of cencern in this chapter since it significantly enhances the performance gain and data rates. Furthermore, this chapter addresses in vivo nano-communication which is presented for medical applications to provide fast and accurate disease diagnosis and treatment. Such communication paradigm is capable of operating inside the human body in real time and will be of great benefit for medical monitoring and medical implant communications. Consequently, propagation at the Terahertz (THz) frequency must be well understood as it is considered the most promising band for electromagnetic nano-communication models.

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