Open source and DIY hardware for DNA nanotechnology labs

Damase, Tulsi Ram; Stephens, Daniel L.; Spencer, Adam; Allen, Peter B.

doi:10.14440/jbm.2015.72

Cited by 40 publications

(33 citation statements)

References 24 publications

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“…The do-it-yourself (DIY) DNA lab designed by Peter Allen, PhD, and his colleagues at the University of Idaho incorporates 3D-printed components for an estimated cost savings of 50% to 90%. 14 Savings can be found in even the most basic plastic tools: a simple gel electrophoresis comb can retail for $6, but the materials of a 3D-printed comb can be less than $0.10.…”

Section: Saving Money With “Pennies’ Worth Of Plastic”mentioning

confidence: 99%

3D Printing in the Laboratory: Maximize Time and Funds with Customized and Open-Source Labware

2016

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3D printing, also known as additive manufacturing, is the computer-guided process of fabricating physical objects by depositing successive layers of material. It has transformed manufacturing across virtually every industry, bringing about incredible advances in research and medicine. The rapidly growing consumer market now includes convenient and affordable “desktop” 3D printers. These are being used in the laboratory to create custom 3D-printed equipment, and a growing community of designers are contributing open-source, cost-effective innovations that can be used by both professionals and enthusiasts. User stories from investigators at the National Institutes of Health and the biomedical research community demonstrate the power of 3D printing to save valuable time and funding. While adoption of 3D printing has been slow in the biosciences to date, the potential is vast. The market predicts that within several years, 3D printers could be commonplace within the home; with so many practical uses for 3D printing, we anticipate that the technology will also play an increasingly important role in the laboratory.

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Section: Saving Money With “Pennies’ Worth Of Plastic”mentioning

confidence: 99%

3D Printing in the Laboratory: Maximize Time and Funds with Customized and Open-Source Labware

2016

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“…There are numerous examples of FOSH scientific equipment in all fields, ranging from syringe pumps [6] to self-assembling robots [7]. Examples exist in the field of biology [8][9][10][11][12], optics [13], and microfluidics [14,15]. Many open tools exist for physics and materials, including radial stretching systems with force sensors [16], a robot-assisted mass spectrometry assay platform [17], a large stage four-point probe [18], and automated microscopes [19].…”

Section: Introductionmentioning

confidence: 99%

General Design Procedure for Free and Open-Source Hardware for Scientific Equipment

Oberloier

Pearce

2017

Designs

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Distributed digital manufacturing of free and open-source scientific hardware (FOSH) used for scientific experiments has been shown to in general reduce the costs of scientific hardware by 90-99%. In part due to these cost savings, the manufacturing of scientific equipment is beginning to move away from a central paradigm of purchasing proprietary equipment to one in which scientists themselves download open-source designs, fabricate components with digital manufacturing technology, and then assemble the equipment themselves. This trend introduces a need for new formal design procedures that designers can follow when targeting this scientific audience. This study provides five steps in the procedure, encompassing six design principles for the development of free and open-source hardware for scientific applications. A case study is provided for an open-source slide dryer that can be easily fabricated for under $20, which is more than 300 times less than some commercial alternatives. The bespoke design is parametric and easily adjusted for many applications. By designing using open-source principles and the proposed procedures, the outcome will be customizable, under control of the researcher, less expensive than commercial options, more maintainable, and will have many applications that benefit the user since the design documentation is open and freely accessible.

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“…Also, they are compatible with a wide range of different needles, which can be used as nozzles. To minimise the need to customise the syringes, a motorised drive system was designed, which is often used for DIY syringe pumps [13,14]. Other advantages of a motorised piston drive include the fact that it does not require an external pumping system, and the improved extrusion control, especially for viscous materials [1], in comparison to pneumatic systems.…”

Section: Introductionmentioning

confidence: 99%

Development of an Extruder for Open Source 3D Bioprinting

Banović¹,

Vihar

2018

Journal of Open Hardware

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Bioprinting has gained significant traction in recent years due to it's implications for medicine and research with a growing spectrum of potential applications. The focus of this work lies on developing an open-source piston driven syringe extruder with thermo-regulation, that is compatible with various CNC systems but also provides broad control and functionality. The manuscript describes the construction and evaluation of the extruder, as well as extrusion parameters and tested fabrication capabilities.

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Open source and DIY hardware for DNA nanotechnology labs

Cited by 40 publications

References 24 publications

3D Printing in the Laboratory: Maximize Time and Funds with Customized and Open-Source Labware

3D Printing in the Laboratory: Maximize Time and Funds with Customized and Open-Source Labware

General Design Procedure for Free and Open-Source Hardware for Scientific Equipment

Development of an Extruder for Open Source 3D Bioprinting

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