Oocyte Donation and In Vitro Fertilization for Hypergonadotropic Hypogonadism

Chan, Casey K.; Cameron, I. T.; Findlay, Jock K.; Healy, David; Leeton, John; Lutjen, P.; Renou, Peter; Rogers, Peter A. W.; Trounson, Alan; Wood, E. C.

doi:10.1097/00006254-198706000-00002

Cited by 22 publications

(2 citation statements)

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“…At present in vitro fertilization with the use of donor oocytes has proven to be the most effective approach to helping many of these patients achieve a pregnancy and has been successful in more than 70% of appropriately selected individuals. [49][50][51] However, recent data indicate that the risk of aortic rupture is increased markedly in women with Turner syndrome during pregnancy. 52 Even an echocardiogram to exclude dilatation of the aortic root prior to pregnancy in women with Turner syndrome does not eliminate this risk because the aortic wall is abnormal in women with this disorder.…”

Section: Special Considerations For Adolescentsmentioning

confidence: 99%

Section: Special Considerations For Adolescentsmentioning

confidence: 99%

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Premature Ovarian “Failure” in the Adolescent

Rebar

2008

Annals of the New York Academy of Sciences

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Premature ovarian "failure" (POF) is an enigmatic and heterogeneous disorder characterized by amenorrhea, hypoestrogenism, and hypergonadotropinism that occurs in women under the age of 40 years. The predominant causes are different in the adolescent, and more of these causes are associated with permanent cessation of ovarian function. It would seem that the more common causes of POF in adolescents include cytogenetic abnormalities involving the X chromosome, ovarian dysfunction occurring in association with other autoimmune endocrine disturbances, and chemotherapy and/or radiation therapy given for any of a number of malignancies. Special challenges in the adolescent beyond establishing the diagnosis include counseling the young woman and her family and discussing the possibility of future pregnancy. Lifelong therapy must be addressed as well. Any discussion of POF raises numerous unanswered questions that should be the focus of future research.

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Section: Special Considerations For Adolescentsmentioning

confidence: 99%

Section: Special Considerations For Adolescentsmentioning

confidence: 99%